Mustela nigripes (black-footed ferret): 132005179
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Entry
132005179 CDS
T09425
Symbol
HSD17B2
Name
(RefSeq) 17-beta-hydroxysteroid dehydrogenase type 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00140
Steroid hormone biosynthesis
mnp01100
Metabolic pathways
mnp04913
Ovarian steroidogenesis
Module
mnp_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
132005179 (HSD17B2)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
132005179 (HSD17B2)
Enzymes [BR:
mnp01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
132005179 (HSD17B2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
132005179 (HSD17B2)
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Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Epimerase
Motif
Other DBs
NCBI-GeneID:
132005179
NCBI-ProteinID:
XP_059238014
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All DBs
Position
17:53692707..53769387
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AA seq
375 aa
AA seq
DB search
MWLCLTVTVVLGGIALCNARKSPGQAGGKVVWLAGLWGGAYLLLSLSLSWSLILCLLSCF
LLYTYLSGQELLPVDQKAVLITGGDSGFGHALSKYLDELGFTVFVGVLDEKGSGAEDLRR
ICSKRLSVLQMDVTDPQQIKDAHSKVVEKVQNRGLWALVNNAGILGLPADGELIPMTGYK
KCMAVNFFGAVEVTKAFLPLLRKSKGRLVNISSMAGGVPMEKLAAYSASKAALTMFSAVM
RQELSKWGVKVSVIQPGGFRTNIAGTSEAWSKHEKDILDHLTSDVQEDYGQDYILQQRNY
LKLINTKASADVSPVLLDIRHAVSAKSPFAFYAPGAMAYSLLCLVSFSPTGVLDYFSKKL
CSLGGGMPRALRRPN
NT seq
1128 nt
NT seq
+upstream
nt +downstream
nt
atgtggctctgcctgactgtcactgttgtgctgggaggcatagctctttgcaatgccagg
aagagcccggggcaggctggaggaaaggtggtctggctggcaggcctctggggaggggct
tacctgctgctcagcctgtccctgtcctggagcctgatcctctgcctcctgtcctgtttc
ctcctgtatacctacctgtctggtcaggagctgctacctgtggatcaaaaggcagtgctg
atcacaggtggcgattccggatttggccatgctctgtccaaatacttggatgaacttggc
ttcacggtatttgtgggagttctggatgaaaagggatccggagcagaggacttgcgaaga
atctgctccaagcgcctctctgtgctccagatggatgtcaccgacccacagcagataaaa
gatgcccacagcaaagtggtggaaaaggtgcagaacagaggtctgtgggctctggtcaac
aacgctggcatcctcggcttgccagctgacggcgagctcattcccatgaccgggtacaaa
aaatgcatggctgtgaacttcttcggggctgtggaggtcacgaaggcatttttgcctctt
ctaaggaaatccaagggcaggctggtgaacatcagtagcatggcaggaggggtcccaatg
gaaaagctggcagcctatagcgcatccaaggcggctctgaccatgttctcagcagtcatg
agacaagagctttccaaatggggagttaaagtctccgtcatccagcctggaggcttcaga
acaaatatcgcaggcaccagtgaagcgtggagcaagcatgagaaggacatcctggaccac
cttacctccgatgtgcaggaggactacggccaggactatatccttcagcaacgcaactat
cttaagctcatcaacacgaaggccagtgcagatgtgtcccctgtgctcctggacatccga
catgctgtgtctgctaagagcccctttgccttttatgcgccaggggcaatggcttattcc
ttgctctgcttggtttcctttagtcctactggtgtacttgattattttagcaaaaaactg
tgtagccttggagggggcatgcccagagcgctaagaaggcctaactga
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