Ovis aries (sheep): 101103973
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Entry
101103973 CDS
T03117
Symbol
AASS
Name
(RefSeq) alpha-aminoadipic semialdehyde synthase, mitochondrial isoform X2
KO
K14157
alpha-aminoadipic semialdehyde synthase [EC:
1.5.1.8
1.5.1.9
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00310
Lysine degradation
oas01100
Metabolic pathways
Module
oas_M00032
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
101103973 (AASS)
Enzymes [BR:
oas01000
]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.8 saccharopine dehydrogenase (NADP+, L-lysine-forming)
101103973 (AASS)
1.5.1.9 saccharopine dehydrogenase (NAD+, L-glutamate-forming)
101103973 (AASS)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Sacchrp_dh_C
AlaDh_PNT_N
Sacchrp_dh_NADP
AlaDh_PNT_C
DUF2325
Shikimate_DH
Motif
Other DBs
NCBI-GeneID:
101103973
NCBI-ProteinID:
XP_012032421
EnsemblRapid:
ENSOARG00020002396
UniProt:
W5QB58
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All DBs
Position
4:complement(88113541..88199754)
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AA seq
926 aa
AA seq
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MLRVSRTKLGRLSPSLSRGLHHKAVMALRREDVNAWERRAPLAPRHVKGITNLGYKVLIQ
PSNRRAIHDKEYVKAGGILQEDISEACLILGVKRPPEEKLMPKKTYAFFSHTIKAQEANM
GLLDEILKQEIRLIDYEKMVDHRGIRVVAFGQWAGVAGMINILHGMGLRLLALGHHTPFM
HIGMAHNYRNSGQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQEIFNELPC
EYVEPHELKEVSQNGDLRKVYGTVLSRHHHLVRKTDGVYDPVEYDKYPERYISRFNTDIA
PYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKSPVAGVEGCPALPHKLVAICDISADTG
GSIEFMTECTTIERPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIESTEYFGDMLY
PYVEEMILSDATQPLESQNFSPVVRDAVITSNGMLSNKYKYIQKLRENRERAQSLSMGTK
KKVLVLGSGYVSEPVLEYLSRDDSIEITVGSDMKNQIEQLGKKYNINPVSLHIGKQEEEL
SSLVATQDLVISLLPYVLHPLVAKACIASKVNMITASYITPALKELEKSVEDAGITVIGE
LGLDPGLDHMLAMETIDKAKEVGATIESYVSYCGGLPAPEYSDNPLRYKFSWSPVGVLMN
IMQPATYLLNGKVVNAVGGVSFLDSVTPMDYFPGLNLEGYPNRDSTKYAEIYGIPSAHTL
LRGTLRYKGYAKALSGFVKLGLINRDAFPALQPDANPLTWKELLCDLVGISSSSKCDVLK
EAVFKKLGGDTTQLEALEWLGLLGDEQVPQAESLVDALSKHLAVKLSYGPGEKDMIVMRD
SFGIRHPSGHLENKTIDLVVYGDVNGFSAMAKTVGLPTAMAAKMLLDGEIQAKGLMGPFS
KEIYGPILERIKAEGIMYTTQSTIKL
NT seq
2781 nt
NT seq
+upstream
nt +downstream
nt
atgctgcgagtgtccagaaccaaactgggcaggctgagccccagcctctccagagggctt
caccacaaggcggtgatggccttgaggcgggaggatgtgaatgcctgggaaaggcgggct
cctctggctccccggcacgtcaaagggatcaccaacctgggatacaaggtcttaatacag
ccttccaatcggcgagccattcacgataaggaatatgtcaaagctggtggcattctccag
gaggatatttctgaagcttgtctaattttgggagttaaaagaccaccagaggaaaaatta
atgcccaagaagacttatgcattcttctcccacacaataaaggctcaggaggccaatatg
ggtttgctggatgagatcctaaaacaggaaatccgacttattgattatgagaaaatggtg
gatcatagaggaatacgggtggtggcatttggacagtgggcaggtgtggcagggatgatc
aacattcttcatgggatgggtttaaggctccttgctttgggacatcacacaccttttatg
cacattggcatggctcataactacaggaacagtggtcaggctgtgcaagctgtccgcgat
gctggctatgaaatatctctgggtttgatgccgaagtcaatagggcccttaacatttgtg
ttcacagggactggtaacgtatctaagggagcccaagaaatcttcaatgaattaccttgt
gagtatgtggagccacatgaattaaaagaagtttcccaaaatggagacctgagaaaagtg
tacggaacagtgttaagtcgccatcatcatcttgtcaggaaaacagatggtgtatatgac
cctgtggagtatgacaaataccccgagcgctacattagccgttttaatactgatattgca
ccctatacaacttgtttaattaatgggatctactgggaacagaacacccctcgtctactc
acccgccaagatgctcagagtctcctggctccaggcaagtccccagttgctggtgttgaa
ggctgccctgcattgccacacaaacttgtggcaatctgtgacatttcagctgacacagga
ggatccattgagtttatgactgagtgtacaaccatagagcgtcccttttgcatgtatgat
gcagatcagcatattattcatgacagtgtggaaggctctgggattctgatgtgttccatt
gacaatttgccagcacagcttccaattgaatccacagaatactttggagacatgctttac
ccttatgttgaagaaatgatactctcagatgcaacacagcctcttgaaagtcagaatttt
tctcctgtggtgcgagatgcagtgattacatctaacggcatgttgtctaacaagtataaa
tatatccagaagctccgagagaacagggaacgtgctcagtcactttcaatgggcaccaag
aaaaaggtcttggttcttggatctggttacgtatctgagcctgtattggaatacctgtcg
agagatgacagtattgaaataacagtaggttctgacatgaagaatcaaattgaacaatta
ggcaagaaatataatattaatcctgttagcctgcacattggtaaacaagaagaggagttg
agctccttggtggcaacacaggatcttgtcatcagcttattgccttatgtattgcatcct
cttgtggccaaggcatgcatcgcaagcaaagttaacatgatcactgcaagctacatcacc
ccagcgctaaaagaattagaaaagagtgtggaagatgctggcatcacagtcattggcgaa
ttgggattggaccctggtcttgatcatatgttggcaatggaaacaatagataaggccaaa
gaagtgggagccacgattgaatcttatgtttcctactgcggtggccttccagctcctgaa
tattcagacaatcctttgagatacaaatttagctggagtccagtgggagttctgatgaac
ataatgcagcccgctacctacctgctcaatggaaaggttgtgaatgctgtaggaggtgtc
tcctttctggattcagtcactcccatggattatttccctggattaaatttggaaggttat
cctaacagagacagtacgaagtatgctgagatttatggcattccatctgctcacacttta
ttacgagggacactgaggtacaaggggtatgccaaagctttgagtggatttgtgaagctg
ggtctcataaacagagatgcgtttcctgcccttcagcctgatgccaatccgctcacctgg
aaagaactcctctgtgatctagttgggatttcatcctcttccaaatgtgatgtgcttaag
gaagctgtctttaagaaactgggaggagacacaacccagctggaggctctcgaatggttg
ggcctactcggggatgaacaagtccctcaggccgagtctctcgtggatgccctctccaag
catctggccgtgaaactttcctatggtcctggagagaaagatatgattgtgatgagagac
agctttggaatcagacatccttctggacatttagaaaataaaactattgatcttgtggtt
tatggggatgtcaatggtttttcagccatggctaaaactgtggggttacccactgctatg
gcagccaagatgttacttgatggtgaaattcaagctaaaggcctgatgggacccttttca
aaggagatctatggaccaatattggagcgaattaaagcagaaggcattatgtatactaca
cagagcacaatcaaactataa
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