Ovis aries (sheep): 101110042
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Entry
101110042 CDS
T03117
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3 isoform X2
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
oas
Ovis aries (sheep)
Pathway
oas04137
Mitophagy - animal
oas04140
Autophagy - animal
oas04141
Protein processing in endoplasmic reticulum
oas04210
Apoptosis
oas04932
Non-alcoholic fatty liver disease
oas05010
Alzheimer disease
oas05012
Parkinson disease
oas05014
Amyotrophic lateral sclerosis
oas05020
Prion disease
oas05022
Pathways of neurodegeneration - multiple diseases
oas05160
Hepatitis C
oas05162
Measles
oas05168
Herpes simplex virus 1 infection
oas05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
101110042 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101110042 (EIF2AK3)
04137 Mitophagy - animal
101110042 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
101110042 (EIF2AK3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
101110042 (EIF2AK3)
05162 Measles
101110042 (EIF2AK3)
05168 Herpes simplex virus 1 infection
101110042 (EIF2AK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
101110042 (EIF2AK3)
05012 Parkinson disease
101110042 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
101110042 (EIF2AK3)
05020 Prion disease
101110042 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
101110042 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101110042 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101110042 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oas01001
]
101110042 (EIF2AK3)
Enzymes [BR:
oas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101110042 (EIF2AK3)
Protein kinases [BR:
oas01001
]
Serine/threonine kinases: Other
PEK family [OT]
101110042 (EIF2AK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
101110042
NCBI-ProteinID:
XP_004005950
EnsemblRapid:
ENSOARG00020000964
LinkDB
All DBs
Position
3:complement(59234138..59316285)
Genome browser
AA seq
1114 aa
AA seq
DB search
MERATGPGSLARTLLLPLLLGLVAGTVAARRTSDLLAPTAEAAFGLGAAAAPTSATRVPA
AGAVIAAEVTVEDSEALPAAAGEQEPREPEPEEEPDIRPCGRSLVIISTLDGRISALDPE
NHGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGDLFQWDRDRESMETVPFTVESL
LESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALSCRQWDNDEMEQEEDILLLQRT
QKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTLKPSGNKEQSKIISDVEEQ
EAVMMDTVIKVSVADWKVVAFNKKGGHLEWEYQFCTPIASAWLVKDGKVIPISLFDDTSY
TPSDGVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPTSPKALESVNSEN
AIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYY
LPYYKRERNKRSTQITVRFLDNPNYKNIRKKDPVLLLHWWKEIVGTIVFCIVATTFIVRR
LFHPHPHRQRKESETQCQTENKYDAVSGEANDSSWNDIKNSGYVSRYLTDFEPIQCMGRG
GFGVVFEARNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLEAP
PEKWQEKMDEIWLKDDSTDWPLSSPSPMDVPSVKIRRMDPFSSKERIEIIAPSPHSSRSF
SVGISCGQTSSSDSQFSPLEFSGMDHGNVSKSADAVCQLQDSCLTDCDGEDGTMDGNDEG
HSFELCPSEASPYVGSRERTSSSIVFEDSGCDNASSKEEPRMNQPPVGNHCGNKLTALRH
AGSKSSSEPAVSVSPSRPTTLSLDLTKSSVGKLQPSSPKVYLYIQMQLCRKENLKDWLNS
RCTIEARERSVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTAM
DQDEEDQMVLTPMPGYARHTGQVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYPFG
TQMERVRILTDVRDLKFPPLFTQKYPREYAMVQDMLSPSATERPEAASIIENAIFEDLEF
PGKTVLRQRSRSMSSPGVKHSRHSSSPHSPLPSN
NT seq
3345 nt
NT seq
+upstream
nt +downstream
nt
atggagcgcgccaccggcccggggtcgctggcacggacgctgctactgccgctgcttctg
gggctcgtggccgggacagtggccgcgcggcgcacctctgacctcctcgcaccgacagcg
gaggcggcgttcggcctcggggccgctgcggctcccacctcggctacgcgggtgccggcg
gcgggcgccgtgattgcggccgaagtgacggtggaggactccgaggcgctgccggcagct
gcaggcgagcaggagccgcgggagccggagccggaagaggagcccgatattcggccgtgc
ggcagatcattagtgatcatcagcactttagatggccgaatctctgccttggatcctgag
aatcatgggaaaaagcagtgggatttggacgtggggtctggttccttggtgtcatccagc
cttagcaaaccagaggtatttgggaacaagatgatcattccttccctggatggagacctc
ttccagtgggaccgggatcgtgagagcatggaaacagttccgtttacagtcgaatcactt
cttgaatcgtcttataaatttggagatgatgttgtcttggttggaggaaagtctctcact
acatatggactcagtgcatatagtggaaaggtgaggtacatctgttcggctctgagttgt
cgccagtgggataatgatgaaatggaacaagaagaagacatcttgcttctgcagcgcacc
cagaaaaccgtgagagccgttggacctcgcagtggcaatgagaagtggaatttcagtgtt
ggccactttgaacttcggtatattccagacatggaaactagagccggatttattgaaagc
accttaaagcccagtggaaacaaagaacagtctaaaattatttcagacgtggaagagcag
gaagctgtcatgatggatacagtgataaaggtctccgttgcagattggaaagttgtggcg
tttaataagaagggaggacacctggagtgggaataccagttttgtactcccattgcatct
gcctggttggttaaggatggcaaagtcattcccatcagtctttttgatgatacaagttac
acccccagtgatggagttttagaagatgaagaagatattgtagaagctgcccggggagcc
acagaaaacagtgtttacttgggaatgtacagaggccaactgtatctgcagtcatcagtc
agaatttcagaaaagtttcctacgagtcccaaggccttggaatctgtcaatagtgaaaat
gctatcattcctttgccaaccatcaaatggaaacctctaatccattctccttctagaact
cctgtcttggtggggtctgacgaatttgacaaatgtctcagtaatgataagttttctcac
gaagagtacagtaacggtgcactttcaatcttgcagtatccttatgataatggttattat
ctgccatactataagagggaaagaaacaaacggagcacgcagatcacggtcagatttctt
gacaacccaaattacaagaacatccgcaaaaaggaccctgttcttctcctacactggtgg
aaagaaatagttggaaccatcgtgttttgtattgtagcaacaactttcattgtacgcaga
ctcttccatcctcatcctcacagacaaaggaaggaatctgaaactcagtgtcaaactgaa
aataaatatgatgctgtcagtggagaagctaatgacagtagctggaatgacataaaaaat
tctggatacgtgtcacggtatctaacagactttgaaccaattcagtgcatgggccgtggc
gggtttggagttgtctttgaagctagaaacaaggttgatgactgcaattatgctatcaag
agaatccgtctccccaacagggaattggctcgggagaaggtaatgcgagaagtgaaagcc
ttagccaagcttgaacacccaggaattgtgagatatttcaatgcttggttggaagcgcca
ccagagaagtggcaagaaaaaatggatgaaatttggctaaaagatgacagcacggactgg
ccgctcagctctcctagtcccatggatgtaccttctgttaaaatacgcagaatggatcct
ttctcttcaaaggaacgtattgaaatcatagctccttcgccacacagcagcaggtctttt
tcagttgggatttcctgtggccagaccagttcgtccgatagccagttctctccgctggag
ttttccgggatggaccacggaaatgtgagcaagtcagcagatgcagtatgccaactccag
gacagctgccttacagactgcgatggggaggatggtaccatggatggtaatgatgaaggg
cactcctttgaactttgtccttcggaagcttctccttatgtagggtccagggagcgaacc
tcctcgtctatagtatttgaagattctggctgtgataacgcgtccagcaaagaggagccc
agaatgaaccaaccgcctgtgggcaaccattgtgggaataaactaactgcgctccggcat
gccggtagcaaatcttcttccgaacctgctgtgtctgtttctccgtcaagaccgaccact
ttaagtttagacctcactaaaagctcggtggggaaactccagcccagttcgcccaaggtg
tatctgtacatccagatgcagctgtgcagaaaggaaaacctcaaagactggctgaacagc
cgctgcaccattgaggcgagagaaaggagcgtatgtttgcacatctttctgcagattgca
gaggcggtggagtttctgcacagcaaagggctcatgcacagggacctcaagccttccaac
atattctttacaatggatgatgtggtcaaggttggagattttggattggtgacggcaatg
gaccaagatgaggaagatcagatggttctgaccccaatgccaggttacgccagacacacg
ggacaagtggggaccaagctgtatatgagcccagaacagattcatggcaacagctattct
cataaagtggacatcttttctttgggcctcattctgtttgaattactatacccgttcggc
actcagatggaaagggtcaggatcctaactgatgtaagagatctcaaatttccaccacta
tttactcaaaaataccctcgtgagtatgccatggtgcaagacatgctgtccccatccgct
actgaacggccagaagctgcgagcatcattgaaaacgcgatcttcgaggacttggagttt
ccaggaaagacggtcctcagacagaggtctcgctccatgagctcacccggagtgaaacat
tcaaggcactccagcagcccccacagccctttgcccagcaattag
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