Ovis aries (sheep): 101113685
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Entry
101113685 CDS
T03117
Symbol
ALOX12
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX12 isoform X3
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00590
Arachidonic acid metabolism
oas01100
Metabolic pathways
oas01523
Antifolate resistance
oas04726
Serotonergic synapse
oas04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
101113685 (ALOX12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
101113685 (ALOX12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101113685 (ALOX12)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101113685 (ALOX12)
Enzymes [BR:
oas01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
101113685 (ALOX12)
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Gene cluster
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
101113685
NCBI-ProteinID:
XP_014954081
EnsemblRapid:
ENSOARG00020021553
UniProt:
W5PHM1
A0A8X8M481
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Position
11:26672877..26686502
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AA seq
663 aa
AA seq
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MGRYRILVATGASLFAGSHNRVQLWLVGARGETELELQLRPVRGQKEEFEHEVPGDLGPL
QFVKLRKHHSLVDDAWFCDRITVQGPGACEEAAFPCYRWVQGDGVLCLPEATARLAGNNA
LDVFQRHREKELKERHKIYRWATWKEGLPLTIAAGCEDDLPANMRFHEEKRLDFEWTLKA
GALEMVLKRVYTLLSSWTSLEDFDLIFWGQKSPLAEKVHQRWQDDELFGYQFLNGANPML
LRRCTSLPSRLVLPSGMEELRAQLERELQNGSLFEADFILLDGIPANVIRGEKQYLAAPL
VMLKMDPSGKLLPMVIQIQPPSPISPTPPLFLPSDPPLAWLLAKTWVRNSDFQLHQLQYH
LLNTHLLAEVIAVATMRCLPGLHPVFKLLMPHIRYTMEINTRARTQLISDGGIFDKAVST
GGGGHVHLLRRALAQLTYRSLCPLDDLADRHLLGTPGALYACDALRLWEITARYVEGIVH
LFYHGDDVVKGDPELQAWCREITEVGLRQAQERGFPVSFQSQNQLCHFLTMCVFTCTAQH
GAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMAITWHLGRR
QPDMVPLGHHKEKYFSDPKAKSVLNQFQTDLENLEREITARNEQLDLPYEYLKPSHIENS
VTI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccgcatcctcgtggccaccggggcctcgctcttcgccggctcgcacaac
cgcgtgcagctgtggctggtcggggcgcgcggggaaacggagctggagctgcagctgcgg
ccagtgcggggccagaaggaggagtttgagcacgaagttccgggggacctggggccgttg
cagttcgtgaagttgcgcaaacaccactccctggtggacgacgcgtggttctgcgaccgc
atcacggtgcagggccctggagcctgcgaggaggccgcgttcccgtgctatcgctgggtg
cagggtgacggcgtgctgtgcctgccagaggccaccgcccgcctggcaggaaacaatgca
ttggatgtgttccagagacatcgagagaaggagctgaaagaaagacataagatataccgc
tgggccacctggaaggaagggttacccctgacaatagctgcaggctgtgaggacgatcta
cctgcaaatatgagattccacgaggagaagaggctggactttgagtggacactgaaggca
ggggctctggagatggtcctcaaacgtgtttacaccctcctgagctcctggaccagtctg
gaggattttgatctcatcttctggggccagaagagccccttggctgagaaggttcaccag
cgctggcaggacgatgagttgtttggctaccagtttctcaatggcgccaaccccatgctg
ttgagacgctgcacctctctgccttctcggctggtgctgccctcggggatggaggagcta
cgggcccagctggagagagaactccagaacggttccctgtttgaggctgatttcatcctc
ctggatggaattccagccaacgtgatccgaggagagaagcagtacctggctgcccccctc
gtcatgctcaagatggaccccagtggaaagctgctacccatggtcatccagatccagcct
cccagccccatctccccaaccccaccactgttcctgccctcggatcctccactcgcctgg
ctcctggcaaagacctgggtccgaaattcagatttccaactgcatcagctccaataccat
ttgctcaacacccatctgctggctgaggtcattgccgtggccaccatgaggtgcctccca
gggctgcaccctgtcttcaagctcctgatgccacacatccgctacacgatggaaatcaac
accagggcacggactcagctcatctcagatggaggcatatttgataaagctgtgagcacc
ggtggagggggtcatgtgcacttgctccgccgggccctggctcagctgacctaccgctcc
ctctgtcctcttgacgatctggctgatcgacacctgctgggaaccccaggtgctctctac
gcctgcgatgctttacggctctgggaaatcactgcccggtatgtggaggggattgtccac
ctcttctaccacggggatgacgttgtaaaaggggaccctgagctgcaagcctggtgtcgg
gagatcactgaggtggggctgcgccaggcccaggagcgaggtttccctgtctccttccag
tcccagaatcaactctgccatttccttaccatgtgtgttttcacgtgcactgctcagcat
ggggccatcaaccagggccagctggactggtatgcctgggtccctaatgccccatgcaca
atgcggatgcccccacccaccaccaaggaagatgtgacaatggccaccgtgatgggctca
ctacctgatgtccgacaagcctgtcttcaaatggccatcacgtggcatctgggtcgccgc
cagccagacatggtgcctctggggcatcacaaagaaaagtatttctcagaccccaaggcc
aagtctgtactaaatcaattccaaacagatctggaaaacttggaaagggaaattacagcc
cgcaatgagcaacttgacctgccctatgaatacctaaagcccagccacatagagaacagc
gtcactatttga
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