KEGG   Orcinus orca (killer whale): 101283760
Entry
101283760         CDS       T05247                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4 isoform X1
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor01522  Endocrine resistance
oor04110  Cell cycle
oor04115  p53 signaling pathway
oor04151  PI3K-Akt signaling pathway
oor04218  Cellular senescence
oor04530  Tight junction
oor04660  T cell receptor signaling pathway
oor04933  AGE-RAGE signaling pathway in diabetic complications
oor04934  Cushing syndrome
oor05160  Hepatitis C
oor05162  Measles
oor05163  Human cytomegalovirus infection
oor05164  Influenza A
oor05165  Human papillomavirus infection
oor05166  Human T-cell leukemia virus 1 infection
oor05167  Kaposi sarcoma-associated herpesvirus infection
oor05169  Epstein-Barr virus infection
oor05200  Pathways in cancer
oor05203  Viral carcinogenesis
oor05212  Pancreatic cancer
oor05214  Glioma
oor05218  Melanoma
oor05219  Bladder cancer
oor05220  Chronic myeloid leukemia
oor05222  Small cell lung cancer
oor05223  Non-small cell lung cancer
oor05224  Breast cancer
oor05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:oor00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    101283760 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    101283760 (CDK4)
   04115 p53 signaling pathway
    101283760 (CDK4)
   04218 Cellular senescence
    101283760 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    101283760 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    101283760 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101283760 (CDK4)
   05203 Viral carcinogenesis
    101283760 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    101283760 (CDK4)
   05225 Hepatocellular carcinoma
    101283760 (CDK4)
   05214 Glioma
    101283760 (CDK4)
   05220 Chronic myeloid leukemia
    101283760 (CDK4)
   05218 Melanoma
    101283760 (CDK4)
   05219 Bladder cancer
    101283760 (CDK4)
   05224 Breast cancer
    101283760 (CDK4)
   05222 Small cell lung cancer
    101283760 (CDK4)
   05223 Non-small cell lung cancer
    101283760 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101283760 (CDK4)
   05160 Hepatitis C
    101283760 (CDK4)
   05164 Influenza A
    101283760 (CDK4)
   05162 Measles
    101283760 (CDK4)
   05163 Human cytomegalovirus infection
    101283760 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101283760 (CDK4)
   05169 Epstein-Barr virus infection
    101283760 (CDK4)
   05165 Human papillomavirus infection
    101283760 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    101283760 (CDK4)
   04934 Cushing syndrome
    101283760 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101283760 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oor01001]
    101283760 (CDK4)
Enzymes [BR:oor01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     101283760 (CDK4)
Protein kinases [BR:oor01001]
 Serine/threonine kinases: CMGC group
  CDK family
   101283760 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 101283760
NCBI-ProteinID: XP_004276615
LinkDB
Position
11:complement(45714236..45717242)
AA seq 303 aa
MATPRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKAEG
NPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggctacccctcgatatgagccagtggctgagattggtgttggtgcctatgggacggtg
tataaggcccgtgatccccacagtggccactttgtggccctcaagagcgtaagagtcccc
aatggaggaggtgctggagggggcctgcccatcagcacagtccgtgaggtggctttactg
cggcggctggaggcttttgagcatcccaatgttgtgcggctgatggacgtctgtgccaca
gcccgaactgaccgggagaccaaagtgaccctggtgtttgagcatgtggaccaagaccta
aggacatatctggacaaggcacccccgccaggcttgccagtggagaccatcaaggatctg
atgcgccagtttctaagaggcctagatttccttcatgccaactgcatcgttcatcgagac
ttgaagccagagaacattctggtgacgagtggtgggacagtcaagctggccgacttcggc
ctggccagaatctacagctaccagatggcacttacacctgtggttgttacactctggtac
cgtgctccagaagttcttttgcagtctacatacgcaacacctgtggacatgtggagtgtt
ggctgtatctttgcagagatgtttcgtcgaaagcctctcttctgtggaaactctgaagct
gaccagttaggcaaaatctttgacctgatcggactgcccccagaggatgactggccccga
gatgtgtctctaccccgaggagccttttcccctagagggccccgccccgtgcagtcggtg
gtacctgagatggaagagtctggagcacagctgctgctggagatgctgacttttaaccca
cacaagcggatctctgccttccgagccctgcagcactcctatctacataaggcagaaggt
aacccagagtga

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