Orcinus orca (killer whale): 101284697
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Entry
101284697 CDS
T05247
Symbol
HSD17B2
Name
(RefSeq) 17-beta-hydroxysteroid dehydrogenase type 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00140
Steroid hormone biosynthesis
oor01100
Metabolic pathways
oor04913
Ovarian steroidogenesis
Module
oor_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
101284697 (HSD17B2)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
101284697 (HSD17B2)
Enzymes [BR:
oor01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
101284697 (HSD17B2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
101284697 (HSD17B2)
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Motif
Pfam:
adh_short
adh_short_C2
KR
Epimerase
GDP_Man_Dehyd
Motif
Other DBs
NCBI-GeneID:
101284697
NCBI-ProteinID:
XP_004280152
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Position
20:complement(6461886..6524137)
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AA seq
436 aa
AA seq
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MLIQGVPGLFSPPPFLPLRSNNPGCLQPVFAHLTQQALSTERRRESLRMGTFFSEPGWLC
LTVTAVLGGTIFCKLKKNQGQVGRKVVCLAGLWGGACLLSLSLFWGLILFSLSCFLVYTY
FSGQELLPADQKAVLITGGDSGIGHALSKYLDELGFTVFAGVLDEKGSGAEELRRTCSKR
LSVLQLDVTDPQQIKDAHSKVKEKLQNRGLWAVVNNAGILGLPTDGELIPMTEYKRCMAV
NFFGAVEVTKAFLPLLRKSKGRLVNISSMAGGVPMEKLAAYSSSKAALTMFSAVMRQELS
KWGVKVSVIQPGGFRTNIAGTSDMWDKLEKNILDHLTPDVQEDYGQDYILRERNFLMFMQ
TYSVMDVSPVLLDVQHAISAKSPFAFYAPGKMSYLWLCFVSFSPTGIFDYFSKKMHSHRK
SMPRALSMPNWKNEAM
NT seq
1311 nt
NT seq
+upstream
nt +downstream
nt
atgctcattcaaggtgttccggggctgttttctccccctcccttcttgcctctccgttca
aataacccaggctgcctgcagcctgtctttgcccatttgactcaacaggccctgagcacg
gaaaggagaagagagtctctgagaatgggcactttcttctctgagccaggatggctttgc
ctgactgtcaccgcagtgctgggaggaacaattttttgcaaactcaagaagaaccaaggg
caggtggggagaaaggtggtctgcctggcgggcctctggggaggggcttgcctgctcagc
ctgtccctcttctggggcttgatcctcttctccctgtcatgtttcctcgtatatacttac
ttttctggccaagagttgttacctgcggatcaaaaggcggtgctgatcacaggtggtgat
tctgggattggccatgctttgtccaagtatctggacgagttgggcttcacagtatttgct
ggagttctggatgaaaagggatctggagcagaggaattacgaagaacctgctccaagcgt
ctctccgtgctccagctggacgttaccgacccgcaacagataaaagatgcccacagcaaa
gtgaaggaaaagctgcagaacagaggactgtgggctgtggtcaacaatgctgggatcctt
ggcctcccaactgacggggagctcattcccatgaccgaatacaaacgatgcatggccgtg
aacttcttcggggccgtggaagtcacaaaggcatttttgccccttcttaggaaatccaag
gggaggctggtgaacatcagcagcatggcaggaggggttccaatggagaagttggcagcc
tatagctcatccaaggcagctctgaccatgttttcagcagtcatgagacaagagctatcc
aaatggggagttaaagtctctgtcatccagcctggaggcttccgaacaaacatcgcaggc
acgagtgacatgtgggacaagctggagaaaaacatcctggaccacctcacccctgacgtg
caagaggactacggccaggactatatccttagggaacgcaattttctcatgttcatgcaa
acctactctgtaatggacgtctccccagtcctcttggacgtccagcatgccatctctgct
aagagcccctttgcattttatgcaccggggaaaatgtcttatctgtggctctgctttgtt
tcctttagccctactggcatatttgattattttagcaaaaaaatgcacagccatagaaag
agcatgcccagagcgttaagcatgcctaactggaagaatgaggccatgtag
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