Ochotona princeps (American pika): 101527487
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Entry
101527487 CDS
T07609
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi04137
Mitophagy - animal
opi04140
Autophagy - animal
opi04141
Protein processing in endoplasmic reticulum
opi04210
Apoptosis
opi04932
Non-alcoholic fatty liver disease
opi05010
Alzheimer disease
opi05012
Parkinson disease
opi05014
Amyotrophic lateral sclerosis
opi05020
Prion disease
opi05022
Pathways of neurodegeneration - multiple diseases
opi05160
Hepatitis C
opi05162
Measles
opi05168
Herpes simplex virus 1 infection
opi05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
101527487 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101527487 (EIF2AK3)
04137 Mitophagy - animal
101527487 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
101527487 (EIF2AK3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
101527487 (EIF2AK3)
05162 Measles
101527487 (EIF2AK3)
05168 Herpes simplex virus 1 infection
101527487 (EIF2AK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
101527487 (EIF2AK3)
05012 Parkinson disease
101527487 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
101527487 (EIF2AK3)
05020 Prion disease
101527487 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
101527487 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101527487 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101527487 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
opi01001
]
101527487 (EIF2AK3)
Enzymes [BR:
opi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101527487 (EIF2AK3)
Protein kinases [BR:
opi01001
]
Serine/threonine kinases: Other
PEK family [OT]
101527487 (EIF2AK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
101527487
NCBI-ProteinID:
XP_004590870
LinkDB
All DBs
Position
2:complement(71254385..71354994)
Genome browser
AA seq
1081 aa
AA seq
DB search
MERAVRPGSLVRALLLPLLLALTVGTGAAGRVRDLPAPRTDAAFGLGAAAAPTSAARMPA
AGAVAGAEVTVEDAEALPATTGEPEPRGPGPDDEAELRSPGRSLVIISTLDGRIAALDPE
NHGKKQWDLDVGSGALVSSSLSKPEVFGNKVIIPSLDGDLFQWDRDRESMETVPFTVESL
LERGIEKGEDVMSVAGSALLCCGTAPLCFQVRYICSALGCRRWDGEDMEEEDILLLQRTQ
KTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTFKPSENKEESNIISDVEEQE
AGTMDTVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLVKDGKVIPISLFDDTSYT
PNQEVLEEEEDIVEAARGATESSVYLGMYRGQLYMQSSVRISEKFPTSPKALESVNNDNA
IIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYVFYTYT
LSVKEQDFRNTRRINSGKMNFFPLEREMLSLQRKESETQCQTENKYDAVSGEASDSSWND
LKISGYVSRYLTDFEPIQCLGRGGFGVVFEARNKVDDCNYAIKRIRLPNRELAREKVMRE
VKALAKLEHPGIVRYFNAWLEAPPEKWQEKMDEIWLKDESTDWPLSSPSPMDAPSVKIRR
VGPFSTKEHIEIIAPSLQRSRSFSVGISCGQTSSSESQFSPLEFSGTKQGDISESGGVAS
NLLDSCLTDCDVEDGTMDGNDEGHPFELCPSKASPYSRFRERTSSSIVFEDSGCDNASSK
EEPGARRLRLGSHCANKLSFLRYYSSSSSSSSASEPTLSVSPSRPTTLSLDLTKNTTEKL
QPSSPKVYLYIQMQLCRKENLKDWMSRRCTLEERERSTCLHIFLQITEAVDFLHSKGLMH
RDLKPSNIFFAMDDVVKVGDFGLVTAMDQDEEEQAVLTPMPAYATHTGQVGTKLYMSPEQ
NHGNNYSHKVDIFSLGLILFELLYPFSTQMERVRTLTDVRNLKFPSLFTQKYPQEYVMVQ
GMLSPSPTDRPEAANIIENAVFEELELPGKTVLRQRSRSASSSGTKHSRQPSSSQSPLPG
T
NT seq
3246 nt
NT seq
+upstream
nt +downstream
nt
atggagcgcgccgtgcgcccggggtcgctggtgagggcgctgctgctgcccctgctgctg
gcgctgaccgtgggcaccggggccgcggggcgtgtccgggacctgcccgcgcccagaacg
gacgctgcgttcggcctgggggccgcggccgctcccacgtcggccgcgcgaatgccggcg
gccggggccgtggccggggccgaggtgacggtggaggacgccgaggcgctccctgcgact
acgggcgagccggagccgcgggggccgggccccgacgacgaggctgagctgcgatcgcca
ggcagatcattagtgattatcagcactttagatggcaggattgctgccttggatcctgag
aatcatggcaaaaagcagtgggatttggatgttggatctggtgccttggtttcatccagc
cttagcaaaccagaggtgtttgggaataaggtaatcattccttccctggacggagacctc
ttccagtgggaccgagaccgggagagcatggaaaccgttcctttcacagttgaatctctc
cttgaaagagggatagagaagggagaagacgtaatgtctgttgcaggcagtgccttactg
tgctgtggcacggcacctctgtgttttcaggtgaggtacatctgttccgctctgggttgt
cgccgatgggacggcgaggacatggaggaggaggacatcctgctgctgcagcgcacccag
aagaccgtgcgcgccgtcggccctcgcagtggcaacgagaagtggaatttcagtgttggc
cactttgaacttcggtatattccagacatggaaactagagccggatttattgaaagcacc
tttaagcccagtgagaacaaagaagagtctaacattatttcagatgtggaagaacaggaa
gctggcactatggacacggtgataaaggtctcggttgctgactggaaggtcatggcattc
agcaagaagggaggacatctggagtgggagtaccagttttgtactccaattgcatccgcc
tggctggtgaaggatgggaaagtcattcccatcagcctttttgacgatacaagttacaca
cctaaccaggaagtcttggaagaggaggaagacatagtcgaagcagcccgaggagccaca
gagagcagtgtttatttagggatgtatagaggccagctgtatatgcaatcatccgtcaga
atttcagaaaagtttcccacaagtcccaaagccttggaatccgtcaataacgacaatgca
attattcccctgccaacaatcaaatggaagcccttaattcattccccttcccggactccc
gtcttggtgggatctgatgagtttgacaaatgcctcagtaacgataagttttctcacgag
gaatacagcaatggggcactttcgattctgcagtatccatatgtgttttacacttatact
ctgagtgtaaaggaacaagactttcgaaacaccagacggattaacagtgggaagatgaac
ttttttcctttagaaagagaaatgctttctctccaaaggaaggagtctgaaactcaatgt
cagaccgaaaataaatacgacgctgtaagtggtgaagccagtgacagtagctggaatgat
ctgaaaatctctggatacgtgtcgcgatacctaacagactttgaaccaatccagtgcctg
ggccgtgggggcttcggggttgtctttgaagccagaaacaaagtagatgactgcaattat
gccatcaaaaggatccggctccccaacagggaactggctcgggaaaaggtaatgcgagaa
gtgaaggccttagccaagctcgaacacccgggcatagtcaggtatttcaatgcctggctt
gaagccccaccggagaagtggcaagaaaagatggatgaaatctggctcaaagatgaaagc
acagactggccactcagctcccccagcccgatggatgccccctcagttaaaatccgcaga
gtgggtcctttctctacaaaagaacacattgaaatcatagctccttccctgcaaagaagc
aggtccttctccgtcgggatctcctgcggccagacgagttcgtcggagagccagttttcc
ccgctggaattctccggaacgaagcagggagacatcagcgagtctgggggcgtggcctcc
aacctcctggacagttgccttacagactgcgatgtggaagatgggactatggatggcaac
gatgagggccacccctttgaactctgtccctcgaaagcctctccctacagcaggttcagg
gagaggacctcctcgtctatagtgtttgaggattctggctgcgacaacgcatccagcaaa
gaggagcccggagcccggcggctgcggctcggcagccactgtgctaacaaactgagcttc
ctccggtactacagcagcagcagcagcagcagctctgcttcggaacctaccctgtccgtt
tccccttccaggcccaccacgttaagtctagatctcacaaagaacactactgagaaactc
cagcccagttcccccaaggtgtacctgtacatccagatgcagctgtgccggaaggaaaac
ctcaaagactggatgagcaggcgctgcaccctggaggagagggagcggagcacgtgtctg
cacatcttcctgcagatcactgaggccgtggacttcctgcacagtaaaggactcatgcac
agggacctcaagccctccaacatattctttgcaatggacgacgtggttaaggttggagac
tttggattagtgactgcaatggaccaggacgaggaagagcaggcggttttgactccgatg
ccagcgtatgccacacacacaggacaagtagggaccaaactctatatgagcccagagcag
aatcatggcaacaactactctcataaagtggacatcttttccttgggcctgattctgttt
gagctgctgtaccccttcagcactcagatggagagagtcaggaccttaactgatgtgaga
aatctcaaatttccatcactgtttactcagaagtatcctcaagagtacgtgatggtccaa
ggcatgctgtccccgtcccccactgaccggcccgaagccgcaaacatcatcgaaaacgcc
gtgtttgaggagctggagttgccagggaaaaccgtgctccgacagaggtcacgctccgcg
agctcatcgggaacaaaacactcaagacagcccagcagctcgcaaagccctctgccaggc
acctag
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