Pteropus alecto (black flying fox): 102879346 Help Entry 102879346         CDS       T02993                                  Symbol INSR Name (RefSeq) insulin receptor   KO K04527   insulin receptor [EC:2.7.10.1] Organism pale  Pteropus alecto (black flying fox) Pathway pale04010   MAPK signaling pathway pale04014   Ras signaling pathway pale04015   Rap1 signaling pathway pale04022   cGMP-PKG signaling pathway pale04066   HIF-1 signaling pathway pale04068   FoxO signaling pathway pale04072   Phospholipase D signaling pathway pale04150   mTOR signaling pathway pale04151   PI3K-Akt signaling pathway pale04152   AMPK signaling pathway pale04211   Longevity regulating pathway pale04213   Longevity regulating pathway - multiple species pale04520   Adherens junction pale04910   Insulin signaling pathway pale04913   Ovarian steroidogenesis pale04923   Regulation of lipolysis in adipocytes pale04930   Type II diabetes mellitus pale04931   Insulin resistance pale04932   Non-alcoholic fatty liver disease pale04960   Aldosterone-regulated sodium reabsorption pale05010   Alzheimer disease pale05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:pale00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     102879346 (INSR)    04014 Ras signaling pathway     102879346 (INSR)    04015 Rap1 signaling pathway     102879346 (INSR)    04066 HIF-1 signaling pathway     102879346 (INSR)    04068 FoxO signaling pathway     102879346 (INSR)    04072 Phospholipase D signaling pathway     102879346 (INSR)    04022 cGMP-PKG signaling pathway     102879346 (INSR)    04151 PI3K-Akt signaling pathway     102879346 (INSR)    04152 AMPK signaling pathway     102879346 (INSR)    04150 mTOR signaling pathway     102879346 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     102879346 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     102879346 (INSR)    04923 Regulation of lipolysis in adipocytes     102879346 (INSR)    04913 Ovarian steroidogenesis     102879346 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     102879346 (INSR)   09149 Aging    04211 Longevity regulating pathway     102879346 (INSR)    04213 Longevity regulating pathway - multiple species     102879346 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     102879346 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     102879346 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     102879346 (INSR)    04932 Non-alcoholic fatty liver disease     102879346 (INSR)    04931 Insulin resistance     102879346 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pale01001]     102879346 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:pale04090]     102879346 (INSR) Enzymes [BR:pale01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      102879346 (INSR) Protein kinases [BR:pale01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    102879346 (INSR) CD molecules [BR:pale04090]  Proteins   102879346 (INSR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 B2 Motif Other DBs NCBI-GeneID:  102879346 NCBI-ProteinID:  XP_015448954 LinkDB All DBs Position Unknown AA seq 1341 aa AA seqDB search AAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMI TDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYSLMNITRGSV RIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQ FVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSEPGDPTKCTACRNFYLDGRC VETCPPPYYHFQDWRCVNFSFCLHLHNKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSS NLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEAN LGLIEEISGYLKIRRSYALVSLAFFRKLRLIRGDTLEVGNYSFYALDNQNLRQLWDWSKH HLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSN IRTSFDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPP LRSNDPKSQSHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSV PLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAEDSELYELDYCLKGLKLPSRT WSPPSESEGSQKHNQSEYDDAAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPR PSRKRRALGDVENVTTVAPTAPSFPNTSWTSVPTSLEEHRPFEKVVNKESLVISGLRHFT GYRIELQACNQDAPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKE PNGLIVLYEVSYRRYGDEELHLCVSRRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSW TEATYFYVTDYHVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNP EYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEAETRVAVK TVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRS LRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGD FGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTASSDMWSFGVVLWEITSLAEQPY QGLSNEQVLKFVMDGGYLDQPDNCPERLTELMRMCWQFNPKMRPTFLEIVDLLKDDLHPS FPEVSFFHSEENKAPESEELEMEFEDMESVPLDRSSHSQREEDGGSTLGLKRNYEDHVPY THMNGGKKNGRVLTLPRSSPS NT seq 4026 nt NT seq  +upstreamnt  +downstreamnt gccgccggccatctgtaccccggagaggtatgtcccggcatggatatccggaacaacctc acgaggctgcacgagctggccaactgctcggtcatcgaaggacatttgcagatactgttg atgttcaaaacgaggcctgaggacttccgagacctcagtttccccaaactcatcatgatc actgattacttgctgctcttccgggtctatgggctggagagcctgaaggacctgttcccc aacctcacggtcatccggggctcccgtctcttcttcaactacgcgctggtcatcttcgag atggttcacctgaaggagcttggcctctacagcctgatgaacatcacccggggctctgtc cgcatcgagaagaacaatgagctctgttacctggccaccatcgactggtcacgcatcctg gattcggtggaggataattacatcgtgctgaacaaggacgacaacgaggagtgtggggac atctgtccaggcactgcgaagggcaagaccaactgccctgccaccgtcatcaacgggcag tttgtggagcggtgttggactcacagccattgccagaaagtctgcccgaccatctgtaaa tcgcacggctgcaccgccgaaggcctctgctgccacagcgagtgcctgggcaactgctcc gagcccggcgaccccaccaagtgcacggcctgccgcaacttctacctggacggccggtgt gtggagacctgcccgcccccgtactaccacttccaggactggcgttgcgtgaacttcagc ttctgcctgcacctgcacaacaaatgcaagaactctcggaggcagggctgccaccagtat gtcattcacaataataagtgcatccctgaatgtccctccggatacacgatgaattccagc aacctgatgtgcactccgtgtctaggcccttgtcccaaggtctgtcacctcctggaagga gagaagaccatcgactcggtgacgtccgcccaggagctccgaggctgcaccgtcatcaat gggagccttatcatcaacattcgagggggcaacaatctggcagctgagctagaggccaac ctcggcctcattgaagaaatttcagggtatctgaaaatccgccgttcctacgccctcgtg tctcttgccttcttccggaagctacgtctgattcggggggataccttggaagtcgggaac tactctttctatgccttggacaaccagaacctgaggcagctgtgggactggagcaaacac cacctcaccatcactcaggggaaactcttcttccactataatcccaagctctgcttgtcg gaaattcacaaaatggaggaagtttcaggaaccaaggggcgccaggagaggaacgacatc gccctgaagaccaatggggaccaggcatcctgtgaaaatgaattacttaaattttctaac attcggacgtcttttgacaagatcttgctgaaatgggagccgtactggccccccgacttc cgagacctcctaggcttcatgctgttctacaaagaggccccttatcagaatgtgacagag ttcgatgggcaggatgcatgtggctccaacagctggacggtggtggacattgacccacct ttgaggtccaacgaccctaagtcacagagccaccccgggtggctgatgcggggtctgaag ccctggacccagtatgccatcttcgtcaagaccttggtcaccttttctgatgaacgtcgc acatatggggccaagagtgacatcatctatgtccagacagatgccaccaatccttctgtc cccctggaccccatctcggtttccaactcctcatcccagatcatcctgaagtggaagcct ccttctgaccccaacggcaacatcactcactacctggttttctgggagaggcaggcagag gacagtgagctgtatgagctggattattgcctcaaagggctgaagctgccctcccggacc tggtctccgccgtcggagtcggagggttcccagaagcacaaccagagtgagtacgatgat gccgccggcgaatgctgctcctgccccaagaccgactctcagatcctgaaggagctagag gagtcgtcgttccggaagacattcgaggactacctgcacaatgtggtttttgtccccagg ccatcgaggaagcgcagggcccttggcgacgtggagaatgtgacgacggtcgcacccacg gccccgagttttcccaacacctcctggaccagtgtgcccacgagcttggaggagcaccgg cccttcgagaaagtggtgaacaaagagtcgctggtcatctccggcctgcgccacttcacc ggctatcgcatcgagctgcaggcttgcaaccaggatgcgcccgaggaaaggtgcagtgtg gcagcctacgtcagcgccaggaccatgccggaagccaaggcagatgacatcgttggcccc gtgacccacgaaatcttcgagaacaacgttgttcacttgatgtggcaggagccgaaggaa cccaacggtctgattgtgctgtatgaagtgagctatcgacgatacggcgatgaggagctg cacctctgtgtctcccgcaggcatttcgctctggagcggggctgcaggctgcgtgggctg cccccggggaattacagcgtgcgagtgcgggccacctccctggcaggcaatggctcctgg acggaagccacctatttctacgtgacagactaccacgtcccatcaaatattgcaaaaatt atcatcggtcccctcatctttgtcttcctcttcagcgttgtgatcggaagcatttatctg ttcctgaggaagaggcagccagatgggcccctgggaccgctgtatgcttcttcaaaccct gagtacctcagtgccagtgatgtgttcccctgttctgtgtatgtgccggacgagtgggag gtgcctcgggagaagatcaccctcctgcgagagctggggcagggctccttcggcatggtg tatgagggcaacgccaaggacatcatcaagggtgaggcagagacccgggtggcggtgaag acggtcaacgagtcggccagcctgcgtgagcgcatcgagtttctcaacgaggcctcggtc atgaagggcttcacctgccatcacgtggtccgcctcctgggggtggtgtccaaggggcag ccgacactggtggtgatggagctgatggcccatggagacctgaagagctaccttcgttcc ctgcggcctgaggctgagaacaaccctggccgccctcccccgaccctgcaagagatgatc cagatggcggcggagatcgcggacgggatggcgtacctgaacgccaagaagttcgtgcac cgggacctcgcagctcgaaactgcatggttgcccatgatttcaccgtcaaaatcggagac tttggaatgaccagagacatctacgagacggattactaccggaaagggggcaagggcctg ctccccgtgcggtggatggcgccggaatccctgaaggatggggtcttcactgcttcttca gacatgtggtccttcggcgtggtcctctgggaaatcaccagcttggcagaacagccttac caaggcctgtctaatgagcaggtgttgaaatttgtcatggatggagggtatctggatcaa cccgacaattgtccagagagactcaccgagctgatgcgcatgtgctggcagttcaacccc aagatgcggccgaccttcctggagatcgtcgacctgctcaaggacgacctgcaccccagc tttccggaagtttccttcttccacagtgaggagaacaaggcgcccgagagcgaggagttg gagatggagtttgaggacatggagagcgtccccctggaccggtcctcacactctcagagg gaagaggacggagggtccacgctgggcctgaagcggaattacgaggatcacgtcccctac acccacatgaacgggggcaagaaaaacgggcgggtcctgactctgccacggtctagtcct tcctaa

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