KEGG   PATHWAY: bim00564
Entry
bim00564                    Pathway                                
Name
Glycerophospholipid metabolism - Bombus impatiens (common eastern bumble bee)
Class
Metabolism; Lipid metabolism
Pathway map
bim00564  Glycerophospholipid metabolism
bim00564

Module
bim_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:bim00564]
bim_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:bim00564]
Other DBs
GO: 0006650
Organism
Bombus impatiens (common eastern bumble bee) [GN:bim]
Gene
100742290  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
100744722  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
100740030  glycerol-3-phosphate dehydrogenase, mitochondrial isoform X1 [KO:K00111] [EC:1.1.5.3]
100744835  glycerol-3-phosphate acyltransferase 1, mitochondrial isoform X3 [KO:K00629] [EC:2.3.1.15]
100748352  glycerol-3-phosphate acyltransferase 3 isoform X3 [KO:K13506] [EC:2.3.1.15]
100741980  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha isoform X1 [KO:K13509] [EC:2.3.1.51]
100744413  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
100742906  lysocardiolipin acyltransferase 1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
100742735  lysophospholipid acyltransferase 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
100745376  dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
100743040  phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
100747243  putative phosphatidate phosphatase isoform X1 [KO:K01080] [EC:3.1.3.4]
100742842  phosphatidate phosphatase LPIN3 [KO:K15728] [EC:3.1.3.4]
100744716  phospholipid phosphatase 5 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
100740797  diacylglycerol kinase epsilon isoform X1 [KO:K00901] [EC:2.7.1.107]
100742594  diacylglycerol kinase 1 isoform X1 [KO:K00901] [EC:2.7.1.107]
100743483  diacylglycerol kinase eta isoform X2 [KO:K00901] [EC:2.7.1.107]
100749653  diacylglycerol kinase theta isoform X5 [KO:K00901] [EC:2.7.1.107]
100741807  eye-specific diacylglycerol kinase [KO:K00901] [EC:2.7.1.107]
100743718  cholinephosphotransferase 1 isoform X7 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
100742072  phospholipase D2 [KO:K01115] [EC:3.1.4.4]
100749372  phospholipase D3 isoform X1 [KO:K16860] [EC:3.1.4.4]
100747310  uncharacterized protein LOC100747310 isoform X1 [KO:K01047] [EC:3.1.1.4]
100747217  group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
105680527  acidic phospholipase A2 PA4 isoform X1 [KO:K01047] [EC:3.1.1.4]
100746952  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
105681822  phospholipase A2 [KO:K01047] [EC:3.1.1.4]
100745409  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
100743873  uncharacterized protein LOC100743873 [KO:K01047] [EC:3.1.1.4]
100741972  uncharacterized protein LOC100741972 [KO:K01047] [EC:3.1.1.4]
100745755  85/88 kDa calcium-independent phospholipase A2 [KO:K16343] [EC:3.1.1.4]
100748605  phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
100741953  lysophosphatidylcholine acyltransferase isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
100742195  lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
100743392  group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
100743307  acyl-protein thioesterase 1 isoform X1 [KO:K06130] [EC:3.1.1.5]
100749327  neuropathy target esterase sws isoform X1 [KO:K14676] [EC:3.1.1.5]
100749468  glycerophosphocholine phosphodiesterase GPCPD1 isoform X4 [KO:K18695] [EC:3.1.4.2]
100746556  choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
100750146  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
100747435  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
100741678  choline/ethanolamine kinase isoform X2 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
100748379  choline-phosphate cytidylyltransferase A isoform X1 [KO:K00968] [EC:2.7.7.15]
100745647  ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
100747174  ethanolamine kinase 1 isoform X1 [KO:K00894] [EC:2.7.1.82]
100742302  ethanolamine-phosphate cytidylyltransferase isoform X1 [KO:K00967] [EC:2.7.7.14]
100747062  alanine--glyoxylate aminotransferase 2-like [KO:K14286] [EC:4.2.3.2]
100742746  phosphatidate cytidylyltransferase, photoreceptor-specific [KO:K00981] [EC:2.7.7.41]
100741060  phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
100744383  phosphatidylserine decarboxylase proenzyme, mitochondrial [KO:K01613] [EC:4.1.1.65]
100750130  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial [KO:K00995] [EC:2.7.8.5]
100743121  probable cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
100748853  tafazzin homolog isoform X1 [KO:K13511] [EC:2.3.1.-]
100743056  acyl-CoA:lysophosphatidylglycerol acyltransferase 1 isoform X1 [KO:K13514] [EC:2.3.1.-]
100744347  CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
100747547  lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
bim00010  Glycolysis / Gluconeogenesis
bim00260  Glycine, serine and threonine metabolism
bim00561  Glycerolipid metabolism
bim00562  Inositol phosphate metabolism
bim00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
bim00565  Ether lipid metabolism
bim00620  Pyruvate metabolism
KO pathway
ko00564   
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