KEGG   PATHWAY: hsyr00270
Entry
hsyr00270                   Pathway                                
Name
Cysteine and methionine metabolism - Hibiscus syriacus (Rose-of-Sharon)
Description
Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034].
Class
Metabolism; Amino acid metabolism
Pathway map
hsyr00270  Cysteine and methionine metabolism
hsyr00270

Module
hsyr_M00021  Cysteine biosynthesis, serine => cysteine [PATH:hsyr00270]
hsyr_M00034  Methionine salvage pathway [PATH:hsyr00270]
hsyr_M00368  Ethylene biosynthesis, methionine => ethylene [PATH:hsyr00270]
Other DBs
GO: 0006534 0006555
Organism
Hibiscus syriacus (Rose-of-Sharon) [GN:hsyr]
Gene
120164678  serine acetyltransferase 5-like [KO:K00640] [EC:2.3.1.30]
120118664  serine acetyltransferase 4-like isoform X1 [KO:K00640] [EC:2.3.1.30]
120169298  serine acetyltransferase 5-like [KO:K00640] [EC:2.3.1.30]
120205122  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
120126565  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
120160459  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
120146188  cysteine synthase 2-like [KO:K01738] [EC:2.5.1.47]
120162508  bifunctional L-3-cyanoalanine synthase/cysteine synthase D1-like [KO:K01738] [EC:2.5.1.47]
120162510  bifunctional L-3-cyanoalanine synthase/cysteine synthase D1-like isoform X1 [KO:K01738] [EC:2.5.1.47]
120162556  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
120151382  cysteine synthase [KO:K01738] [EC:2.5.1.47]
120219541  cysteine synthase 2-like [KO:K01738] [EC:2.5.1.47]
120138963  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
120206766  cysteine synthase-like isoform X1 [KO:K01738] [EC:2.5.1.47]
120124683  bifunctional L-3-cyanoalanine synthase/cysteine synthase D1-like [KO:K01738] [EC:2.5.1.47]
120175260  cysteine synthase, chloroplastic/chromoplastic-like isoform X1 [KO:K01738] [EC:2.5.1.47]
120143542  cysteine synthase-like isoform X1 [KO:K01738] [EC:2.5.1.47]
120181544  bifunctional L-3-cyanoalanine synthase/cysteine synthase 1, mitochondrial-like [KO:K13034] [EC:2.5.1.47 4.4.1.9]
120213228  cystathionine beta-lyase, chloroplastic-like isoform X1 [KO:K01760] [EC:4.4.1.13]
120218268  homocysteine S-methyltransferase 3-like [KO:K00547] [EC:2.1.1.10]
120136915  homocysteine S-methyltransferase 2-like isoform X1 [KO:K00547] [EC:2.1.1.10]
120204836  homocysteine S-methyltransferase 3-like [KO:K00547] [EC:2.1.1.10]
120171777  homocysteine S-methyltransferase 1-like isoform X1 [KO:K00547] [EC:2.1.1.10]
120189067  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
120178164  homocysteine S-methyltransferase 1-like [KO:K00547] [EC:2.1.1.10]
120212956  LOW QUALITY PROTEIN: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase-like [KO:K00549] [EC:2.1.1.14]
120148695  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like [KO:K00549] [EC:2.1.1.14]
120164959  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like [KO:K00549] [EC:2.1.1.14]
120116396  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1-like [KO:K00549] [EC:2.1.1.14]
120185329  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase [KO:K00549] [EC:2.1.1.14]
120153659  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like [KO:K00549] [EC:2.1.1.14]
120125869  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like [KO:K00549] [EC:2.1.1.14]
120125870  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like [KO:K00549] [EC:2.1.1.14]
120144557  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like [KO:K00549] [EC:2.1.1.14]
120129547  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
120214227  LOW QUALITY PROTEIN: S-adenosylmethionine synthase 1-like [KO:K00789] [EC:2.5.1.6]
120181005  S-adenosylmethionine synthase 1-like [KO:K00789] [EC:2.5.1.6]
120199625  S-adenosylmethionine synthase 2-like [KO:K00789] [EC:2.5.1.6]
120183136  S-adenosylmethionine synthase 2-like [KO:K00789] [EC:2.5.1.6]
120218491  S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
120136432  S-adenosylmethionine synthase-like [KO:K00789] [EC:2.5.1.6]
120186266  S-adenosylmethionine synthase 1-like [KO:K00789] [EC:2.5.1.6]
120136699  S-adenosylmethionine synthase 2-like [KO:K00789] [EC:2.5.1.6]
120155851  S-adenosylmethionine synthase-like [KO:K00789] [EC:2.5.1.6]
120188810  S-adenosylmethionine synthase 1 [KO:K00789] [EC:2.5.1.6]
120205561  S-adenosylmethionine synthase 1-like [KO:K00789] [EC:2.5.1.6]
120123832  S-adenosylmethionine synthase 3-like [KO:K00789] [EC:2.5.1.6]
120193057  S-adenosylmethionine synthase 1-like [KO:K00789] [EC:2.5.1.6]
120161261  S-adenosylmethionine synthase 2 [KO:K00789] [EC:2.5.1.6]
120213896  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
120165498  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
120133930  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
120134918  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
120201192  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
120169533  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
120189561  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
120208195  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
120178512  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
120178926  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
120136690  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
120188874  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
120148962  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
120215255  spermidine synthase 1 [KO:K00797] [EC:2.5.1.16]
120216126  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
120116883  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
120117166  spermidine synthase-like [KO:K00797] [EC:2.5.1.16]
120184207  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
120171705  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
120140014  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
120206493  spermine synthase-like isoform X1 [KO:K00797] [EC:2.5.1.16]
120178123  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
120117544  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
120157069  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
120189659  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
120124664  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
120214791  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase-like isoform X1 [KO:K01244] [EC:3.2.2.16]
120184817  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase-like isoform X1 [KO:K01244] [EC:3.2.2.16]
120175602  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase-like [KO:K01244] [EC:3.2.2.16]
120120464  methylthioribose kinase-like [KO:K00899] [EC:2.7.1.100]
120120815  methylthioribose kinase-like [KO:K00899] [EC:2.7.1.100]
120169370  methylthioribose-1-phosphate isomerase [KO:K08963] [EC:5.3.1.23]
120114156  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
120122597  LOW QUALITY PROTEIN: probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
120159078  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
120127927  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
120129168  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
120164080  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
120198722  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 1-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
120134941  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 1-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
120218274  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
120218584  probable N-succinyldiaminopimelate aminotransferase DapC [KO:K23977] [EC:2.6.1.117]
120203109  probable N-succinyldiaminopimelate aminotransferase DapC [KO:K23977] [EC:2.6.1.117]
120191339  probable N-succinyldiaminopimelate aminotransferase DapC [KO:K23977] [EC:2.6.1.117]
120163769  probable aminotransferase TAT2 isoform X1 [KO:K00815] [EC:2.6.1.5]
120164566  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
120149632  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
120121410  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
120122656  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
120159342  S-alkyl-thiohydroximate lyase SUR1-like [KO:K00815] [EC:2.6.1.5]
120175650  tyrosine aminotransferase-like isoform X1 [KO:K00815] [EC:2.6.1.5]
120144747  tyrosine aminotransferase-like [KO:K00815] [EC:2.6.1.5]
120133378  aromatic aminotransferase ISS1-like [KO:K00837] [EC:2.6.1.-]
120157353  aromatic aminotransferase ISS1-like [KO:K00837] [EC:2.6.1.-]
120208603  aromatic aminotransferase ISS1-like [KO:K00837] [EC:2.6.1.-]
120114351  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
120199725  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
120202555  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
120120317  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
120186876  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
120120837  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
120206549  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
120191856  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
120199516  DNA (cytosine-5)-methyltransferase CMT2-like [KO:K00558] [EC:2.1.1.37]
120199932  putative DNA (cytosine-5)-methyltransferase CMT1 [KO:K00558] [EC:2.1.1.37]
120140138  DNA (cytosine-5)-methyltransferase CMT3-like isoform X1 [KO:K00558] [EC:2.1.1.37]
120124774  DNA (cytosine-5)-methyltransferase CMT3-like [KO:K00558] [EC:2.1.1.37]
120207736  LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase CMT3-like [KO:K00558] [EC:2.1.1.37]
120176293  DNA (cytosine-5)-methyltransferase 1-like isoform X1 [KO:K00558] [EC:2.1.1.37]
120128587  LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase CMT2-like [KO:K00558] [EC:2.1.1.37]
120145223  putative DNA (cytosine-5)-methyltransferase CMT1 [KO:K00558] [EC:2.1.1.37]
120180561  uncharacterized protein LOC120180561 [KO:K17398] [EC:2.1.1.37]
120157601  uncharacterized protein LOC120157601 [KO:K17398] [EC:2.1.1.37]
120157700  uncharacterized protein LOC120157700 [KO:K17398] [EC:2.1.1.37]
120177741  uncharacterized protein LOC120177741 [KO:K17398] [EC:2.1.1.37]
120177972  uncharacterized protein LOC120177972 isoform X1 [KO:K17398] [EC:2.1.1.37]
120213778  adenosylhomocysteinase 1-like [KO:K01251] [EC:3.13.2.1]
120148816  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
120198190  adenosylhomocysteinase 1 [KO:K01251] [EC:3.13.2.1]
120135061  adenosylhomocysteinase 1-like [KO:K01251] [EC:3.13.2.1]
120158760  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
120175105  adenosylhomocysteinase [KO:K01251] [EC:3.13.2.1]
120128191  adenosylhomocysteinase 1-like [KO:K01251] [EC:3.13.2.1]
120146373  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
120114402  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
120132884  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
120186829  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
120155229  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
120123602  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
120140468  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
120173238  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
120141053  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
120125776  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
120208090  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
120127418  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
120193725  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
120180634  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
120181469  1-aminocyclopropane-1-carboxylate synthase-like [KO:K01762] [EC:4.4.1.14]
120181655  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
120132524  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
120166440  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
120166946  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
120118299  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
120119084  1-aminocyclopropane-1-carboxylate synthase 8-like [KO:K01762] [EC:4.4.1.14]
120167822  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
120218682  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
120203880  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
120122635  1-aminocyclopropane-1-carboxylate synthase-like [KO:K01762] [EC:4.4.1.14]
120123659  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
120156910  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
120140948  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
120157620  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
120159730  1-aminocyclopropane-1-carboxylate synthase CMA101-like [KO:K01762] [EC:4.4.1.14]
120211797  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
120113617  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
120146461  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
120195938  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
120114009  1-aminocyclopropane-1-carboxylate oxidase 3-like [KO:K05933] [EC:1.14.17.4]
120130579  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
120130874  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
120147129  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
120196853  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
120131619  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
120164431  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
120216740  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
120152303  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
120153179  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
120169093  1-aminocyclopropane-1-carboxylate oxidase 5-like [KO:K05933] [EC:1.14.17.4]
120137033  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
120154183  1-aminocyclopropane-1-carboxylate oxidase 3-like [KO:K05933] [EC:1.14.17.4]
120120971  1-aminocyclopropane-1-carboxylate oxidase 3-like [KO:K05933] [EC:1.14.17.4]
120121103  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
120204284  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
120139122  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
120188567  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
120189628  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
120206587  1-aminocyclopropane-1-carboxylate oxidase 5-like [KO:K05933] [EC:1.14.17.4]
120190471  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
120126843  1-aminocyclopropane-1-carboxylate oxidase 3-like [KO:K05933] [EC:1.14.17.4]
120161119  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
120176890  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
120194772  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
120195387  1-aminocyclopropane-1-carboxylate oxidase-like isoform X1 [KO:K05933] [EC:1.14.17.4]
120195475  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
120211921  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
120147583  aspartokinase 2, chloroplastic-like isoform X1 [KO:K00928] [EC:2.7.2.4]
120118648  aspartokinase 2, chloroplastic-like isoform X1 [KO:K00928] [EC:2.7.2.4]
120140312  aspartokinase 2, chloroplastic-like [KO:K00928] [EC:2.7.2.4]
120206148  aspartokinase 2, chloroplastic-like isoform X1 [KO:K00928] [EC:2.7.2.4]
120133797  bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic-like [KO:K12524] [EC:2.7.2.4 1.1.1.3]
120174138  bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic-like [KO:K12524] [EC:2.7.2.4 1.1.1.3]
120216059  aspartate-semialdehyde dehydrogenase-like [KO:K00133] [EC:1.2.1.11]
120134528  aspartate-semialdehyde dehydrogenase-like [KO:K00133] [EC:1.2.1.11]
120203737  aspartate-semialdehyde dehydrogenase-like [KO:K00133] [EC:1.2.1.11]
120122139  aspartate-semialdehyde dehydrogenase-like [KO:K00133] [EC:1.2.1.11]
120146404  cystathionine gamma-synthase 1, chloroplastic-like [KO:K01739] [EC:2.5.1.48]
120131071  cystathionine gamma-synthase 1, chloroplastic-like [KO:K01739] [EC:2.5.1.48]
120147413  cystathionine gamma-synthase 1, chloroplastic-like isoform X1 [KO:K01739] [EC:2.5.1.48]
120130130  branched-chain-amino-acid aminotransferase 5, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
120130578  branched-chain amino acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
120199889  branched-chain-amino-acid aminotransferase 6-like [KO:K00826] [EC:2.6.1.42]
120133919  branched-chain-amino-acid aminotransferase 6-like [KO:K00826] [EC:2.6.1.42]
120216589  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
120218371  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
120138073  branched-chain amino acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
120190832  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
120125614  branched-chain amino acid aminotransferase 2, chloroplastic-like isoform X1 [KO:K00826] [EC:2.6.1.42]
120126737  branched-chain amino acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
120194089  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
120211306  branched-chain-amino-acid aminotransferase 6-like [KO:K00826] [EC:2.6.1.42]
120145488  branched-chain-amino-acid aminotransferase 6-like [KO:K00826] [EC:2.6.1.42]
120212147  branched-chain-amino-acid aminotransferase 5, chloroplastic-like isoform X1 [KO:K00826] [EC:2.6.1.42]
120212554  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
120198581  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
120200735  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
120135072  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
120185637  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
120137919  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
120159780  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
120195607  acetylornithine aminotransferase-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
120213730  glutamate--cysteine ligase, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
120202610  glutamate--cysteine ligase, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
120206702  glutamate--cysteine ligase, chloroplastic-like isoform X1 [KO:K01919] [EC:6.3.2.2]
120191748  glutamate--cysteine ligase, chloroplastic-like isoform X1 [KO:K01919] [EC:6.3.2.2]
120207450  glutathione synthetase, chloroplastic isoform X1 [KO:K21456] [EC:6.3.2.3]
120197705  aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
120149937  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
120149938  aspartate aminotransferase, cytoplasmic-like isoform X1 [KO:K14454] [EC:2.6.1.1]
120192373  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
120169240  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
120139571  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
120139584  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
120149662  aspartate aminotransferase, chloroplastic-like [KO:K00811] [EC:2.6.1.1]
120184949  aspartate aminotransferase, chloroplastic-like [KO:K00811] [EC:2.6.1.1]
120194074  aspartate aminotransferase, chloroplastic-like [KO:K00811] [EC:2.6.1.1]
120162228  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial-like isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
120121587  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial-like isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
120141441  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial-like [KO:K01011] [EC:2.8.1.1 2.8.1.2]
120117416  L-lactate dehydrogenase B-like [KO:K00016] [EC:1.1.1.27]
120187046  L-lactate dehydrogenase B-like [KO:K00016] [EC:1.1.1.27]
120203697  D-cysteine desulfhydrase 2, mitochondrial isoform X1 [KO:K05396] [EC:4.4.1.15]
120173368  bifunctional D-cysteine desulfhydrase/1-aminocyclopropane-1-carboxylate deaminase, mitochondrial-like [KO:K05396] [EC:4.4.1.15]
120135361  L-cysteine desulfhydrase-like [KO:K22207] [EC:4.4.1.28]
120167386  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
120136396  L-cysteine desulfhydrase-like [KO:K22207] [EC:4.4.1.28]
120189662  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
120114588  malate dehydrogenase-like [KO:K00025] [EC:1.1.1.37]
120201195  malate dehydrogenase 2, cytoplasmic-like [KO:K00025] [EC:1.1.1.37]
120201499  malate dehydrogenase, cytoplasmic-like [KO:K00025] [EC:1.1.1.37]
120218296  malate dehydrogenase 2, cytoplasmic-like [KO:K00025] [EC:1.1.1.37]
120208294  malate dehydrogenase [KO:K00025] [EC:1.1.1.37]
120161360  malate dehydrogenase, cytoplasmic-like [KO:K00025] [EC:1.1.1.37]
120114150  malate dehydrogenase, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
120132457  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
120181371  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
120199920  malate dehydrogenase, glyoxysomal [KO:K00026] [EC:1.1.1.37]
120134689  malate dehydrogenase, glyoxysomal-like [KO:K00026] [EC:1.1.1.37]
120201665  malate dehydrogenase, glyoxysomal-like [KO:K00026] [EC:1.1.1.37]
120168867  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
120219449  malate dehydrogenase, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
120205239  malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
120125638  malate dehydrogenase, glyoxysomal-like [KO:K00026] [EC:1.1.1.37]
120142806  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
120158576  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
120113880  S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent), chloroplastic-like isoform X1 [KO:K22846] [EC:2.5.1.144]
120153904  S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent), chloroplastic-like isoform X1 [KO:K22846] [EC:2.5.1.144]
120201447  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
120120611  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
120122048  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
120155685  D-3-phosphoglycerate dehydrogenase 3, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
120142708  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
120144828  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
120163131  phosphoserine aminotransferase 2, chloroplastic-like [KO:K00831] [EC:2.6.1.52]
120183807  phosphoserine aminotransferase 2, chloroplastic-like [KO:K00831] [EC:2.6.1.52]
120152462  phosphoserine aminotransferase 2, chloroplastic-like [KO:K00831] [EC:2.6.1.52]
Compound
C00019  S-Adenosyl-L-methionine
C00021  S-Adenosyl-L-homocysteine
C00022  Pyruvate
C00041  L-Alanine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00065  L-Serine
C00073  L-Methionine
C00094  Sulfite
C00097  L-Cysteine
C00109  2-Oxobutanoate
C00155  L-Homocysteine
C00170  5'-Methylthioadenosine
C00197  3-Phospho-D-glycerate
C00263  L-Homoserine
C00283  Hydrogen sulfide
C00409  Methanethiol
C00441  L-Aspartate 4-semialdehyde
C00491  L-Cystine
C00506  L-Cysteate
C00606  3-Sulfino-L-alanine
C00793  D-Cysteine
C00957  Mercaptopyruvate
C00979  O-Acetyl-L-serine
C01005  O-Phospho-L-serine
C01077  O-Acetyl-L-homoserine
C01118  O-Succinyl-L-homoserine
C01137  S-Adenosylmethioninamine
C01180  4-Methylthio-2-oxobutanoic acid
C01234  1-Aminocyclopropane-1-carboxylate
C01817  L-Homocystine
C01962  Thiocysteine
C02218  Dehydroalanine
C02291  L-Cystathionine
C02356  (S)-2-Aminobutanoate
C02989  L-Methionine S-oxide
C03082  4-Phospho-L-aspartate
C03089  5-Methylthio-D-ribose
C03145  N-Formylmethionine
C03232  3-Phosphonooxypyruvate
C03431  S-Inosyl-L-homocysteine
C03539  S-Ribosyl-L-homocysteine
C04188  S-Methyl-5-thio-D-ribose 1-phosphate
C04582  S-Methyl-5-thio-D-ribulose 1-phosphate
C05324  Nicotianamine
C05524  Aminoacyl-L-methionine
C05526  S-Glutathionyl-L-cysteine
C05527  3-Sulfinylpyruvate
C05528  3-Sulfopyruvate
C05823  3-Mercaptolactate
C05824  S-Sulfo-L-cysteine
C06547  Ethylene
C08276  3-(Methylthio)propanoate
C09306  Sulfur dioxide
C11437  1-Deoxy-D-xylulose 5-phosphate
C11481  HSO3-
C11499  (S)-3-Sulfolactate
C11537  (2R)-3-Sulfolactate
C15606  1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one
C15650  2,3-Diketo-5-methylthiopentyl-1-phosphate
C15651  2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate
C18049  N-Acyl-L-homoserine lactone
C19787  5'-S-Methyl-5'-thioinosine
C21015  gamma-L-Glutamyl-L-2-aminobutyrate
C21016  Ophthalmate
C22359  S-Methyl-1-thio-D-xylulose 5-phosphate
Reference
PMID:15102328
  Authors
Sekowska A, Denervaud V, Ashida H, Michoud K, Haas D, Yokota A, Danchin A
  Title
Bacterial variations on the methionine salvage pathway.
  Journal
BMC Microbiol 4:9 (2004)
DOI:10.1186/1471-2180-4-9
Reference
PMID:14551435
  Authors
Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A.
  Title
A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO.
  Journal
Science 302:286-90 (2003)
DOI:10.1126/science.1086997
Reference
PMID:12022921
  Authors
Sekowska A, Danchin A.
  Title
The methionine salvage pathway in Bacillus subtilis.
  Journal
BMC Microbiol 2:8 (2002)
DOI:10.1186/1471-2180-2-8
Reference
PMID:12670965
  Authors
Berger BJ, English S, Chan G, Knodel MH.
  Title
Methionine regeneration and aminotransferases in Bacillus subtilis, Bacillus cereus, and Bacillus anthracis.
  Journal
J Bacteriol 185:2418-31 (2003)
DOI:10.1128/JB.185.8.2418-2431.2003
Reference
PMID:17169919
  Authors
Goyer A, Collakova E, Shachar-Hill Y, Hanson AD
  Title
Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway.
  Journal
Plant Cell Physiol 48:232-42 (2007)
DOI:10.1093/pcp/pcl055
Reference
PMID:17030798
  Authors
Rebeille F, Jabrin S, Bligny R, Loizeau K, Gambonnet B, Van Wilder V, Douce R, Ravanel S
  Title
Methionine catabolism in Arabidopsis cells is initiated by a gamma-cleavage process and leads to S-methylcysteine and isoleucine syntheses.
  Journal
Proc Natl Acad Sci U S A 103:15687-92 (2006)
DOI:10.1073/pnas.0606195103
Reference
PMID:18625006
  Authors
Pirkov I, Norbeck J, Gustafsson L, Albers E
  Title
A complete inventory of all enzymes in the eukaryotic methionine salvage pathway.
  Journal
FEBS J 275:4111-20 (2008)
DOI:10.1111/j.1742-4658.2008.06552.x
Reference
PMID:18391471
  Authors
Ashida H, Saito Y, Kojima C, Yokota A
  Title
Enzymatic characterization of 5-methylthioribulose-1-phosphate dehydratase of the methionine salvage pathway in Bacillus subtilis.
  Journal
Biosci Biotechnol Biochem 72:959-67 (2008)
DOI:10.1271/bbb.70651
Reference
PMID:10613873
  Authors
Kitabatake M, So MW, Tumbula DL, Soll D
  Title
Cysteine biosynthesis pathway in the archaeon Methanosarcina barkeri encoded by acquired bacterial genes?
  Journal
J Bacteriol 182:143-5 (2000)
DOI:10.1128/JB.182.1.143-145.2000
Reference
PMID:12644499
  Authors
Mino K, Ishikawa K
  Title
Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1.
  Journal
J Bacteriol 185:2277-84 (2003)
DOI:10.1128/JB.185.7.2277-2284.2003
Reference
PMID:18520135
  Authors
Tanabe S
  Title
Development of assay methods for endogenous inorganic sulfur compounds and sulfurtransferases and evaluation of the physiological functions of bound sulfur.
  Journal
Yakugaku Zasshi 128:881-900 (2008)
DOI:10.1248/yakushi.128.881
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
PMID:19270684
  Authors
Gutierrez JA, Crowder T, Rinaldo-Matthis A, Ho MC, Almo SC, Schramm VL
  Title
Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.
  Journal
Nat Chem Biol 5:251-7 (2009)
DOI:10.1038/nchembio.153
Related
pathway
hsyr00010  Glycolysis / Gluconeogenesis
hsyr00250  Alanine, aspartate and glutamate metabolism
hsyr00260  Glycine, serine and threonine metabolism
hsyr00290  Valine, leucine and isoleucine biosynthesis
hsyr00430  Taurine and hypotaurine metabolism
hsyr00480  Glutathione metabolism
hsyr00620  Pyruvate metabolism
hsyr00640  Propanoate metabolism
hsyr00770  Pantothenate and CoA biosynthesis
hsyr00900  Terpenoid backbone biosynthesis
hsyr00920  Sulfur metabolism
KO pathway
ko00270   
LinkDB

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