KEGG   PATHWAY: msyl00564
Entry
msyl00564                   Pathway                                
Name
Glycerophospholipid metabolism - Malus sylvestris (European crab apple)
Class
Metabolism; Lipid metabolism
Pathway map
msyl00564  Glycerophospholipid metabolism
msyl00564

Module
msyl_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:msyl00564]
Other DBs
GO: 0006650
Organism
Malus sylvestris (European crab apple) [GN:msyl]
Gene
126582813  glycerol-3-phosphate dehydrogenase [NAD(+)]-like [KO:K00006] [EC:1.1.1.8]
126598631  glycerol-3-phosphate dehydrogenase [NAD(+)] GPDHC1, cytosolic-like [KO:K00006] [EC:1.1.1.8]
126610792  glycerol-3-phosphate dehydrogenase [NAD(+)]-like [KO:K00006] [EC:1.1.1.8]
126610794  glycerol-3-phosphate dehydrogenase [NAD(+)]-like [KO:K00006] [EC:1.1.1.8]
126611045  glycerol-3-phosphate dehydrogenase [NAD(+)] GPDHC1, cytosolic-like [KO:K00006] [EC:1.1.1.8]
126628437  probable glycerol-3-phosphate dehydrogenase [NAD(+)] 1, cytosolic [KO:K00006] [EC:1.1.1.8]
126629567  glycerol-3-phosphate dehydrogenase [NAD(+)] 2, chloroplastic [KO:K00006] [EC:1.1.1.8]
126594586  glycerol-3-phosphate dehydrogenase [NAD(+)] GPDHC1, cytosolic [KO:K00006] [EC:1.1.1.8]
126629965  glycerol-3-phosphate dehydrogenase SDP6, mitochondrial-like [KO:K00111] [EC:1.1.5.3]
126630693  glycerol-3-phosphate dehydrogenase SDP6, mitochondrial-like isoform X1 [KO:K00111] [EC:1.1.5.3]
126587425  glycerol-3-phosphate acyltransferase 9-like [KO:K13506] [EC:2.3.1.15]
126624505  glycerol-3-phosphate acyltransferase 9 [KO:K13506] [EC:2.3.1.15]
126625713  glycerol-3-phosphate acyltransferase, chloroplastic isoform X1 [KO:K00630] [EC:2.3.1.15]
126606640  glycerol-3-phosphate acyltransferase, chloroplastic-like isoform X1 [KO:K00630] [EC:2.3.1.15]
126582459  glycerol-3-phosphate acyltransferase 1-like [KO:K13508] [EC:2.3.1.15 2.3.1.198]
126582461  glycerol-3-phosphate acyltransferase 1-like [KO:K13508] [EC:2.3.1.15 2.3.1.198]
126611188  glycerol-3-phosphate acyltransferase 1-like [KO:K13508] [EC:2.3.1.15 2.3.1.198]
126612559  probable glycerol-3-phosphate acyltransferase 3 [KO:K13508] [EC:2.3.1.15 2.3.1.198]
126627927  glycerol-3-phosphate acyltransferase 5-like isoform X1 [KO:K13508] [EC:2.3.1.15 2.3.1.198]
126628782  probable glycerol-3-phosphate acyltransferase 8 [KO:K13508] [EC:2.3.1.15 2.3.1.198]
126630922  probable glycerol-3-phosphate acyltransferase 3 [KO:K13508] [EC:2.3.1.15 2.3.1.198]
126618335  glycerol-3-phosphate 2-O-acyltransferase 6-like [KO:K13508] [EC:2.3.1.15 2.3.1.198]
126592885  glycerol-3-phosphate 2-O-acyltransferase 6-like [KO:K13508] [EC:2.3.1.15 2.3.1.198]
126605365  probable glycerol-3-phosphate acyltransferase 3 [KO:K13508] [EC:2.3.1.15 2.3.1.198]
126634195  probable glycerol-3-phosphate acyltransferase 3 [KO:K13508] [EC:2.3.1.15 2.3.1.198]
126622358  glycerol-3-phosphate acyltransferase 5-like isoform X1 [KO:K13508] [EC:2.3.1.15 2.3.1.198]
126613869  1-acyl-sn-glycerol-3-phosphate acyltransferase BAT2, chloroplastic-like isoform X1 [KO:K00655] [EC:2.3.1.51]
126605207  1-acyl-sn-glycerol-3-phosphate acyltransferase BAT2, chloroplastic-like [KO:K00655] [EC:2.3.1.51]
126599227  1-acyl-sn-glycerol-3-phosphate acyltransferase 2-like [KO:K13523] [EC:2.3.1.51 2.3.1.-]
126614758  1-acyl-sn-glycerol-3-phosphate acyltransferase 3-like [KO:K13523] [EC:2.3.1.51 2.3.1.-]
126614759  1-acyl-sn-glycerol-3-phosphate acyltransferase PLS1-like [KO:K13523] [EC:2.3.1.51 2.3.1.-]
126590779  1-acyl-sn-glycerol-3-phosphate acyltransferase 3-like [KO:K13523] [EC:2.3.1.51 2.3.1.-]
126593107  1-acyl-sn-glycerol-3-phosphate acyltransferase 2-like [KO:K13523] [EC:2.3.1.51 2.3.1.-]
126587538  probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 5 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
126632152  probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 4 isoform X1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
126603794  probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 4 isoform X1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
126626419  lysophospholipid acyltransferase 1-like [KO:K13519] [EC:2.3.1.51 2.3.1.23 2.3.1.-]
126617624  lysophospholipid acyltransferase 1-like [KO:K13519] [EC:2.3.1.51 2.3.1.23 2.3.1.-]
126598443  triacylglycerol lipase SDP1-like [KO:K14674] [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
126592791  triacylglycerol lipase SDP1 [KO:K14674] [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
126600770  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
126604046  phosphatidate phosphatase PAH2-like [KO:K15728] [EC:3.1.3.4]
126617861  phosphatidate phosphatase PAH1-like [KO:K15728] [EC:3.1.3.4]
126592757  phosphatidate phosphatase PAH1-like [KO:K15728] [EC:3.1.3.4]
126633124  phosphatidate phosphatase PAH2-like [KO:K15728] [EC:3.1.3.4]
126583201  lipid phosphate phosphatase 2-like isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
126609658  putative lipid phosphate phosphatase 3, chloroplastic isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
126599370  lipid phosphate phosphatase 2-like [KO:K18693] [EC:3.6.1.75 3.1.3.4]
126597022  lipid phosphate phosphatase 2-like [KO:K18693] [EC:3.6.1.75 3.1.3.4]
126597023  lipid phosphate phosphatase 2-like [KO:K18693] [EC:3.6.1.75 3.1.3.4]
126608813  lipid phosphate phosphatase 1-like isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
126608814  lipid phosphate phosphatase 2-like [KO:K18693] [EC:3.6.1.75 3.1.3.4]
126624955  lipid phosphate phosphatase 2-like isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
126583386  diacylglycerol kinase 5-like isoform X1 [KO:K00901] [EC:2.7.1.107]
126610475  diacylglycerol kinase 5-like isoform X1 [KO:K00901] [EC:2.7.1.107]
126626306  diacylglycerol kinase 1-like isoform X1 [KO:K00901] [EC:2.7.1.107]
126599614  diacylglycerol kinase 1-like [KO:K00901] [EC:2.7.1.107]
126588195  diacylglycerol kinase 1-like [KO:K00901] [EC:2.7.1.107]
126605485  diacylglycerol kinase 2 isoform X1 [KO:K00901] [EC:2.7.1.107]
126607090  diacylglycerol kinase 7-like [KO:K00901] [EC:2.7.1.107]
126596844  diacylglycerol kinase 4 [KO:K00901] [EC:2.7.1.107]
126598542  LOW QUALITY PROTEIN: non-specific phospholipase C6-like [KO:K01114] [EC:3.1.4.3]
126626450  non-specific phospholipase C6 [KO:K01114] [EC:3.1.4.3]
126628042  non-specific phospholipase C3-like [KO:K01114] [EC:3.1.4.3]
126628043  non-specific phospholipase C3-like [KO:K01114] [EC:3.1.4.3]
126615199  non-specific phospholipase C2-like [KO:K01114] [EC:3.1.4.3]
126615335  non-specific phospholipase C1-like [KO:K01114] [EC:3.1.4.3]
126588694  non-specific phospholipase C2-like [KO:K01114] [EC:3.1.4.3]
126589036  non-specific phospholipase C1-like [KO:K01114] [EC:3.1.4.3]
126610132  phospholipase D alpha 4-like [KO:K01115] [EC:3.1.4.4]
126598826  phospholipase D delta-like [KO:K01115] [EC:3.1.4.4]
126611533  phospholipase D alpha 1-like [KO:K01115] [EC:3.1.4.4]
126628648  phospholipase D gamma 1-like [KO:K01115] [EC:3.1.4.4]
126601437  phospholipase D alpha 1-like isoform X1 [KO:K01115] [EC:3.1.4.4]
126604152  phospholipase D delta-like [KO:K01115] [EC:3.1.4.4]
126618958  phospholipase D zeta 1-like [KO:K01115] [EC:3.1.4.4]
126619447  phospholipase D gamma 1-like isoform X1 [KO:K01115] [EC:3.1.4.4]
126592552  phospholipase D zeta 1-like [KO:K01115] [EC:3.1.4.4]
126604450  phospholipase D delta-like [KO:K01115] [EC:3.1.4.4]
126633331  phospholipase D delta-like [KO:K01115] [EC:3.1.4.4]
126593001  phospholipase D alpha 1-like [KO:K01115] [EC:3.1.4.4]
126634451  phospholipase D alpha 4-like [KO:K01115] [EC:3.1.4.4]
126596276  phospholipase D zeta 1-like isoform X1 [KO:K01115] [EC:3.1.4.4]
126608236  phospholipase D zeta 1-like isoform X1 [KO:K01115] [EC:3.1.4.4]
126582036  phospholipase D alpha 1 [KO:K01115] [EC:3.1.4.4]
126601352  uncharacterized protein LOC126601352 isoform X1 [KO:K16860] [EC:3.1.4.4]
126597403  phospholipase A2-alpha-like isoform X1 [KO:K01047] [EC:3.1.1.4]
126606347  phospholipase A2-alpha-like isoform X1 [KO:K01047] [EC:3.1.1.4]
126628807  lysophospholipid acyltransferase LPEAT2-like [KO:K13510] [EC:2.3.1.23 2.3.1.67]
126601609  lysophospholipid acyltransferase LPEAT1-like isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
126632201  lysophospholipid acyltransferase LPEAT1-like isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
126605360  lysophospholipid acyltransferase LPEAT2-like [KO:K13510] [EC:2.3.1.23 2.3.1.67]
126611415  phospholipase A(1) DAD1, chloroplastic-like [KO:K16818] [EC:3.1.1.32]
126630098  phospholipase A(1) DAD1, chloroplastic [KO:K16818] [EC:3.1.1.32]
126586455  lecithin-cholesterol acyltransferase-like 4 [KO:K22389] [EC:3.1.1.32]
126618369  phospholipase A(1) LCAT3-like [KO:K22389] [EC:3.1.1.32]
126591777  phospholipase A(1) LCAT3-like [KO:K22389] [EC:3.1.1.32]
126623694  lecithin-cholesterol acyltransferase-like 4 isoform X1 [KO:K22389] [EC:3.1.1.32]
126611492  uncharacterized protein LOC126611492 isoform X1 [KO:K06130] [EC:3.1.1.5]
126631133  uncharacterized protein LOC126631133 isoform X1 [KO:K06130] [EC:3.1.1.5]
126603277  uncharacterized protein LOC126603277 [KO:K06130] [EC:3.1.1.5]
126604259  acyl-protein thioesterase 1-like [KO:K06130] [EC:3.1.1.5]
126593364  acyl-protein thioesterase 1-like [KO:K06130] [EC:3.1.1.5]
126634240  uncharacterized protein LOC126634240 [KO:K06130] [EC:3.1.1.5]
126583817  glycerophosphodiester phosphodiesterase GDPD1, chloroplastic-like [KO:K18696] [EC:3.1.4.46]
126612157  glycerophosphodiester phosphodiesterase GDPD1, chloroplastic-like [KO:K18696] [EC:3.1.4.46]
126596849  glycerophosphodiester phosphodiesterase GDPD2-like [KO:K18696] [EC:3.1.4.46]
126608444  glycerophosphodiester phosphodiesterase GDPD2-like [KO:K18696] [EC:3.1.4.46]
126625629  glycerophosphodiester phosphodiesterase GDPD6-like [KO:K01126] [EC:3.1.4.46]
126599748  glycerophosphodiester phosphodiesterase GDPD6-like isoform X1 [KO:K01126] [EC:3.1.4.46]
126585023  probable choline kinase 1 isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
126613727  probable choline kinase 2 isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
126629633  probable choline kinase 2 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
126621017  probable choline kinase 1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
126582584  choline-phosphate cytidylyltransferase 2-like [KO:K00968] [EC:2.7.7.15]
126611094  choline-phosphate cytidylyltransferase 2-like isoform X1 [KO:K00968] [EC:2.7.7.15]
126584610  choline-phosphate cytidylyltransferase 1-like [KO:K00968] [EC:2.7.7.15]
126623728  choline-phosphate cytidylyltransferase 1-like [KO:K00968] [EC:2.7.7.15]
126593394  choline/ethanolaminephosphotransferase 1-like isoform X1 [KO:K00993] [EC:2.7.8.1]
126608756  choline/ethanolaminephosphotransferase 1 isoform X1 [KO:K00993] [EC:2.7.8.1]
126586705  serine decarboxylase-like [KO:K25193] [EC:4.1.1.-]
126621901  serine decarboxylase-like [KO:K25193] [EC:4.1.1.-]
126604419  probable ethanolamine kinase [KO:K00894] [EC:2.7.1.82]
126593168  probable ethanolamine kinase [KO:K00894] [EC:2.7.1.82]
126597399  ethanolamine-phosphate cytidylyltransferase-like isoform X1 [KO:K00967] [EC:2.7.7.14]
126619224  ethanolamine-phosphate cytidylyltransferase-like [KO:K00967] [EC:2.7.7.14]
126593920  ethanolamine-phosphate cytidylyltransferase-like [KO:K00967] [EC:2.7.7.14]
126607919  ethanolamine-phosphate cytidylyltransferase-like [KO:K00967] [EC:2.7.7.14]
126598789  phosphoethanolamine N-methyltransferase 1 [KO:K05929] [EC:2.1.1.103]
126626484  phosphoethanolamine N-methyltransferase 1-like [KO:K05929] [EC:2.1.1.103]
126609987  phosphatidyl-N-methylethanolamine N-methyltransferase [KO:K00550] [EC:2.1.1.71]
126586317  phosphatidate cytidylyltransferase 1-like [KO:K00981] [EC:2.7.7.41]
126630039  phosphatidate cytidylyltransferase 4, chloroplastic isoform X1 [KO:K00981] [EC:2.7.7.41]
126623955  phosphatidate cytidylyltransferase 1-like [KO:K00981] [EC:2.7.7.41]
126596505  CDP-diacylglycerol--serine O-phosphatidyltransferase 1-like [KO:K08730] [EC:2.7.8.29]
126608483  CDP-diacylglycerol--serine O-phosphatidyltransferase 1-like [KO:K08730] [EC:2.7.8.29]
126626656  phosphatidylserine decarboxylase proenzyme 1, mitochondrial [KO:K01613] [EC:4.1.1.65]
126631018  phosphatidylserine decarboxylase proenzyme 3-like isoform X1 [KO:K01613] [EC:4.1.1.65]
126629302  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2-like [KO:K00995] [EC:2.7.8.5]
126620786  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1, chloroplastic [KO:K00995] [EC:2.7.8.5]
126582740  phosphatidylglycerophosphate phosphatase 1, chloroplastic/mitochondrial-like [KO:K01094] [EC:3.1.3.27]
126611203  phosphatidylglycerophosphate phosphatase 1, chloroplastic/mitochondrial-like [KO:K01094] [EC:3.1.3.27]
126586209  cardiolipin synthase (CMP-forming), mitochondrial [KO:K08744] [EC:2.7.8.41]
126624260  cardiolipin synthase (CMP-forming), mitochondrial-like [KO:K08744] [EC:2.7.8.41]
126603218  N-acylphosphatidylethanolamine synthase-like [KO:K13511] [EC:2.3.1.-]
126618979  uncharacterized protein LOC126618979 [KO:K13511] [EC:2.3.1.-]
126594471  uncharacterized protein LOC126594471 [KO:K13511] [EC:2.3.1.-]
126608419  N-acylphosphatidylethanolamine synthase-like isoform X1 [KO:K13511] [EC:2.3.1.-]
126586339  probable CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2 [KO:K00999] [EC:2.7.8.11]
126622025  CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1 [KO:K00999] [EC:2.7.8.11]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
msyl00010  Glycolysis / Gluconeogenesis
msyl00260  Glycine, serine and threonine metabolism
msyl00561  Glycerolipid metabolism
msyl00562  Inositol phosphate metabolism
msyl00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
msyl00565  Ether lipid metabolism
msyl00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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