PATHWAY: rn00361 Help
Entry
Name
Chlorocyclohexane and chlorobenzene degradation
Class
Metabolism; Xenobiotics biodegradation and metabolism
Pathway map
rn00361 Chlorocyclohexane and chlorobenzene degradation
Ortholog table
Module
M00547 Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol [PATH:rn00361 ]
Other DBs
Reaction
R00812 cis-1,2-dihydrobenzene-1,2-diol:NAD+ oxidoreductase
R03543 benzene,NADH:oxygene 1,2-oxidoreductase
R03891 benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (decyclizing)
R03893 4-carboxymethylenebut-2-en-4-olide lactonohydrolase
R03982 pentachlorophenol,NADPH:oxygen oxidoreductase (hydroxylating, dechloronating)
R03997 2,4-dichlorophenol,NADPH:oxygen oxidoreductase(6-hydroxylating)
R04259 (2R)-2-chloro-2,5-dihydro-5-oxofuran-2-acetate lyase (ring-opening)
R04576 cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide cis-trans-isomerase
R05236 4-hydroxymuconic-semialdehyde:NAD+ oxidoreductase
R05243 2,5-dichloro-2,5-cyclohexadiene-1,4-diol:NAD+ oxidoreductase
R05287 chloroacetic acid halidohydrolase
R05369 1,3,4,6-tetrachloro-1,4-cyclohexadiene chlorohydrolase
R05386 gamma-hexachlorocyclohexane chloride-lyase
R05387 gamma-pentachlorocyclohexene chloride-lyase
R05388 5-chloro-1,2,4-trihydroxybenzene chloride-lyase
R05397 3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene:NAD+ oxidoreductase
R05399 NADH:2-hydroxy-1,4-benzoquinone oxidoreductase
R05402 glutathione disulfide:2,6-dichlorohydroquinone (chlorinating)
R05403 glutathione disulfide:2,6-dichlorohydroquinone (chlorinating)
R05406 catechol:oxygen 2,3-oxidoreductase (ring-opening)
R05429 1,4-dichlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)
R05441 4-chlorophenol,NADPH:oxygen oxidoreductase (6-hydroxylating)
R05449 2,4,6-trichlorophenol,FADH2:oxygen oxidoreductase (dechlorinating)
R05510 protoanemonin lactonohydrolase
R06831 1,2,4-trichlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)
R06832 3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene:NAD+ oxidoreductase
R06833 catechol:oxygen 1,2-oxidoreductase
R06834 2-chloro-2,5-dihydro-5-oxofuran-2-acetate lyase
R06835 4-carboxymethylenebut-2-en-4-olide lactonohydrolase
R06838 4-carboxymethylenebut-2-en-4-olide lactonohydrolase
R06839 catechol:oxygen 1,2-oxidoreductase
R06840 2-chloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)
R06848 3-oxoadipate:NAD(P)+ oxidoreductase
R06856 chlorobenzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)
R06857 (1R,2R)-3-chlorocyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase
R07669 beta-hexachlorocyclohexane halidohydrolase
R07670 beta-2,3,4,5,6-pentachlorocyclohexanol halidohydrolase
R07827 3-chlorocatechol:oxygen 1,2-oxidoreductase (decyclizing)
R09134 tetrachlorocatechol:oxygen 1,2-oxidoreductase
R09135 2,3,5-trichlorodienelactone lyase (decyclizing)
R09136 2,3,5-trichlorodienelactone lactonohydrolase
R09137 2,4-dichloro-3-oxoadipate:NAD+ oxidoreductase
R09138 2,4-dichloro-3-oxoadipate:NADP+ oxidoreductase
R10042 benzene,NADH:oxygen oxidoreductase
R10043 phenol,NADH:oxygen oxidoreductase (2-hydroxylating)
R11585 2,3,5,6-tetrachlorohydroquinone:NAD+ oxidoreductase
Compound
C00682 2-Hydroxymuconate semialdehyde
C03434 Tetrachlorohydroquinone
C03572 2-Chloro-cis,cis-muconate
C03585 3-Chloro-cis,cis-muconate
C03664 2,4-Dichlorophenoxyacetate
C03918 2,4-Dichloro-cis,cis-muconate
C04091 cis-1,2-Dihydrobenzene-1,2-diol
C04431 cis-4-Carboxymethylenebut-2-en-4-olide
C04522 2-Chloro-2,5-dihydro-5-oxofuran-2-acetate
C04706 cis-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide
C04729 trans-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide
C06328 6-Chlorobenzene-1,2,4-triol
C06596 gamma-Pentachlorocyclohexene
C06597 1,3,4,6-Tetrachloro-1,4-cyclohexadiene
C06598 2,4,5-Trichloro-2,5-cyclohexadiene-1-ol
C06599 2,5-Dichloro-2,5-cyclohexadiene-1,4-diol
C06600 2,5-Dichlorohydroquinone
C06603 cis,cis-4-Hydroxymuconic semialdehyde
C06988 beta-1,2,3,4,5,6-Hexachlorocyclohexane
C06989 delta-3,4,5,6-Tetrachlorocyclohexene
C07089 5-Chloro-2-hydroxymuconic semialdehyde
C07093 3,6-Dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene
C07095 2,5-Dichloro-cis,cis-muconate
C07097 2,6-Dichlorohydroquinone
C07099 2,3,6-Trichlorohydroquinone
C07100 2,4,5-Trichlorophenoxyacetic acid
C07102 5-Chloro-1,2,4-trihydroxybenzene
C07103 2-Hydroxy-1,4-benzoquinone
C11352 5,6-Dichloro-1,3-cyclohexadiene
C12831 3,4,6-Trichlorocatechol
C12832 3,4,6-Trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene
C12833 2,3,5-Trichloro-cis,cis-muconate
C12834 2,5-Dichloro-carboxymethylenebut-2-en-4-olide
C12835 2,5-Dichloro-4-oxohex-2-enedioate
C12837 3-Chloro-cis-1,2-dihydroxycyclohexa-3,5-diene
C12838 trans-4-Carboxymethylenebut-2-en-4-olide
C16181 beta-2,3,4,5,6-Pentachlorocyclohexanol
C16182 beta-2,3,5,6-Tetrachloro-1,4-cyclohexanediol
C16266 3-Chloro-2-hydroxymuconic semialdehyde
C18236 1,2,3,4-Tetrachlorobenzene
C18238 cis-Chlorobenzene dihydrodiol
C18241 Tetrachloro-cis,cis-muconate
C18242 2,3,5-Trichlorodienelactone
C18243 2,3,5-Trichloromaleylacetate
C18244 2,4-Dichloro-3-oxoadipate
C21103 2,6-Dichloro-p-benzoquinone
C21104 2,5-Dichloro-p-benzoquinone
C21105 5-Chloro-2-hydroxy-p-benzoquinone
Reference
Authors
Xun L, Bohuslavek J, Cai M.
Title
Characterization of 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA) of Sphingomonas chlorophenolica ATCC 39723.
Journal
Reference
Authors
van der Meer JR, van Neerven AR, de Vries EJ, de Vos WM, Zehnder AJ.
Title
Cloning and characterization of plasmid-encoded genes for the degradation of 1,2-dichloro-, 1,4-dichloro-, and 1,2,4-trichlorobenzene of Pseudomonas sp. strain P51.
Journal
Reference
Authors
Nagata Y, Futamura A, Miyauchi K, Takagi M.
Title
Two different types of dehalogenases, LinA and LinB, involved in gamma-hexachlorocyclohexane degradation in Sphingomonas paucimobilis UT26 are localized in the periplasmic space without molecular processing.
Journal
Reference
Authors
Nagata Y, Miyauchi K, Takagi M.
Title
Complete analysis of genes and enzymes for gamma-hexachlorocyclohexane degradation in Sphingomonas paucimobilis UT26.
Journal
Reference
Authors
Dogra C, Raina V, Pal R, Suar M, Lal S, Gartemann KH, Holliger C, van der Meer JR, Lal R.
Title
Organization of lin genes and IS6100 among different strains of hexachlorocyclohexane-degrading Sphingomonas paucimobilis: evidence for horizontal gene transfer.
Journal
Reference
Authors
Nagata Y, Prokop Z, Marvanova S, Sykorova J, Monincova M, Tsuda M, Damborsky J.
Title
Reconstruction of mycobacterial dehalogenase Rv2579 by cumulative mutagenesis of haloalkane dehalogenase LinB.
Journal
Reference
Authors
Vedler E, Vahter M, Heinaru A.
Title
The completely sequenced plasmid pEST4011 contains a novel IncP1 backbone and a catabolic transposon harboring tfd genes for 2,4-dichlorophenoxyacetic acid degradation.
Journal
Reference
Authors
Sommer C, Gorisch H.
Title
Enzymology of the degradation of (di)chlorobenzenes by Xanthobacter flavus 14p1.
Journal
Reference
Authors
Laemmli CM, Schonenberger R, Suter M, Zehnder AJ, van der Meer JR.
Title
TfdD(II), one of the two chloromuconate cycloisomerases of Ralstonia eutropha JMP134 (pJP4), cannot efficiently convert 2-chloro- cis, cis-muconate to trans-dienelactone to allow growth on 3-chlorobenzoate.
Journal
Reference
Authors
Wu J, Hong Q, Han P, He J, Li S.
Title
A gene linB2 responsible for the conversion of beta-HCH and 2,3,4,5,6-pentachlorocyclohexanol in Sphingomonas sp. BHC-A.
Journal
Reference
Authors
Potrawfke T, Timmis KN, Wittich RM
Title
Degradation of 1,2,3,4-tetrachlorobenzene by pseudomonas chlororaphis RW71
Journal
Reference
Authors
Potrawfke T, Armengaud J, Wittich RM
Title
Chlorocatechols substituted at positions 4 and 5 are substrates of the broad-spectrum chlorocatechol 1,2-dioxygenase of Pseudomonas chlororaphis RW71.
Journal
Related pathway
rn00630 Glyoxylate and dicarboxylate metabolism
KO pathway
LinkDB
All DBs