Pongo abelii (Sumatran orangutan): 100456547
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Entry
100456547 CDS
T01416
Symbol
HSD17B2
Name
(RefSeq) estradiol 17-beta-dehydrogenase 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon00140
Steroid hormone biosynthesis
pon01100
Metabolic pathways
pon04913
Ovarian steroidogenesis
Module
pon_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100456547 (HSD17B2)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
100456547 (HSD17B2)
Enzymes [BR:
pon01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
100456547 (HSD17B2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
100456547 (HSD17B2)
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Motif
Pfam:
adh_short
adh_short_C2
KR
Epimerase
Ins_allergen_rp
DUF4131
Motif
Other DBs
NCBI-GeneID:
100456547
NCBI-ProteinID:
XP_002826735
Ensembl:
ENSPPYG00000007591
UniProt:
H2NRL5
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Position
16:60032950..60096300
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AA seq
386 aa
AA seq
DB search
MSTFFSDTAWICLAVPTVLCGTVFCKYKSSGQPWSWMVCLAGLCAVCLLILSPFWGLILF
SVSCFLTYTYLSGQELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGA
EELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLP
MTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSIGGGAPMARMASYGSSKAAVTM
FSSVMRMELSKWGIKVVSIQPGGFRTNIAGTSDKWEKLEKDILDHLPAEVQEDYGQDYIL
AQRNFLLLINSAASTDFSPVLRDIQHAISAKSPFAYYTPGKAAYLWLCLAHYLPIGIYDY
FAKRNFCQDKPMPRALSMPNYKKKAT
NT seq
1161 nt
NT seq
+upstream
nt +downstream
nt
atgagcactttcttctcggacacagcatggatctgcctggctgtccccactgtactatgt
gggacagtattttgcaaatacaagagctcggggcagccgtggagctggatggtctgcctg
gcaggcctctgtgcagtctgcctgctcatcctgtcccctttttggggcttgatcctcttc
tcggtgtcatgtttcctcacgtatacttacttatctggccaagagttgttacctgtggat
cagaaggcagtcctggtgacaggtggtgattgcgggcttggccacgctttgtgcaagtat
ctggatgagctgggcttcacggtatttgccggagttttgaatgaaaatggcccaggagct
gaggaattgcgaagaacctgctctccgcgtctctcggtgctccaaatggacatcacgaag
ccagtgcagataaaagatgcttacagcaaggttgcagcaatgctgcaggacagaggactg
tgggctgtgatcaacaatgctggggtgcttggctttccaactgatggggagcttcttcct
atgactgactacaaacaatgcatggccgtgaacttctttggaactgtggaggtcacaaag
acatttttgcctcttcttagaaaatccaaagggaggctggtgaatgtcagcagcatagga
ggaggggccccaatggcaaggatggcatcttatggctcatcaaaggcagctgtgaccatg
ttctcatcagttatgagaatggagctttccaagtggggaattaaagttgtttccatccaa
cctggaggcttccgaacaaatatcgcaggcacgagtgacaagtgggaaaagctggagaag
gacattctggaccacctccctgctgaggtgcaggaagactacggccaggactacatctta
gcgcagcggaatttcctcctattgatcaactcggcagccagtacggacttctctccggtg
ctgcgggacatccagcatgctatctcggcgaagagcccttttgcctattacacgccaggg
aaagccgcttacttgtggctctgccttgctcactatttgcctattggcatatatgattac
tttgctaaaagaaatttttgccaagacaagcccatgcccagagctctaagcatgcctaac
tataagaaaaaggccacctag
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