Phodopus roborovskii (desert hamster): 127237189 Help Entry 127237189         CDS       T08852                                  Symbol Insr Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism prob  Phodopus roborovskii (desert hamster) Pathway prob04010   MAPK signaling pathway prob04014   Ras signaling pathway prob04015   Rap1 signaling pathway prob04022   cGMP-PKG signaling pathway prob04066   HIF-1 signaling pathway prob04068   FoxO signaling pathway prob04072   Phospholipase D signaling pathway prob04150   mTOR signaling pathway prob04151   PI3K-Akt signaling pathway prob04152   AMPK signaling pathway prob04211   Longevity regulating pathway prob04213   Longevity regulating pathway - multiple species prob04520   Adherens junction prob04910   Insulin signaling pathway prob04913   Ovarian steroidogenesis prob04923   Regulation of lipolysis in adipocytes prob04930   Type II diabetes mellitus prob04931   Insulin resistance prob04932   Non-alcoholic fatty liver disease prob04960   Aldosterone-regulated sodium reabsorption prob05010   Alzheimer disease prob05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:prob00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     127237189 (Insr)    04014 Ras signaling pathway     127237189 (Insr)    04015 Rap1 signaling pathway     127237189 (Insr)    04066 HIF-1 signaling pathway     127237189 (Insr)    04068 FoxO signaling pathway     127237189 (Insr)    04072 Phospholipase D signaling pathway     127237189 (Insr)    04022 cGMP-PKG signaling pathway     127237189 (Insr)    04151 PI3K-Akt signaling pathway     127237189 (Insr)    04152 AMPK signaling pathway     127237189 (Insr)    04150 mTOR signaling pathway     127237189 (Insr)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     127237189 (Insr)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     127237189 (Insr)    04923 Regulation of lipolysis in adipocytes     127237189 (Insr)    04913 Ovarian steroidogenesis     127237189 (Insr)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     127237189 (Insr)   09149 Aging    04211 Longevity regulating pathway     127237189 (Insr)    04213 Longevity regulating pathway - multiple species     127237189 (Insr)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     127237189 (Insr)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     127237189 (Insr)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     127237189 (Insr)    04932 Non-alcoholic fatty liver disease     127237189 (Insr)    04931 Insulin resistance     127237189 (Insr)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:prob01001]     127237189 (Insr)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:prob04090]     127237189 (Insr) Enzymes [BR:prob01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      127237189 (Insr) Protein kinases [BR:prob01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    127237189 (Insr) CD molecules [BR:prob04090]  Proteins   127237189 (Insr) BRITE hierarchy Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 Motif Other DBs NCBI-GeneID:  127237189 NCBI-ProteinID:  XP_051061251 LinkDB All DBs Position Unknown AA seq 1372 aa AA seqDB search MGSGRRRETTAAPLLVAVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELENCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDVCPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHKECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHYKCRNSRKPG CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCQILDGEKTIDSVTSAQELRGC TVINGSLIINIRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSFIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVT FSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVY WERQAEDSELFELDYCLKGLKLPSRTWSPPFESDESQKHNQSEYDDSASECCSCPKTDSQ ILKELEESSFRKTFEDYLHNVVFVPRPSRKRRSLEEVGNVTATMPALPDFPNISSTVVPT SQEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPDERCSVAAYVSARTMPEAKA DDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERG CRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSV VIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEVPREKITLLRELG QGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLL GVVSKGQPTLVVMELMAHGDLKSHLRSLRPDAENNPGRPPPTLQEMIQMTAEIADGMAYL NAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKD GVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDPPDNCPERLTDLMR MCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFYSEENKAPESEELEMEFEDMENVPLD GSSHFHREEAGGREGGSSLSIKRTYDEHIPYTHMNGGKKNGRVLTLPRSNPS NT seq 4119 nt NT seq  +upstreamnt  +downstreamnt atgggatccgggagacgacgtgagacgacggccgcgccgttgctggtggccgtggccgcg ttgctggtgggcgcagctggccacctgtaccctggagaggtgtgccctggcatggacatc cggaacaacctgacccggctgcatgagctggagaactgctcagttattgagggccacctg cagatcctcctgatgttcaaaaccaggcccgaagacttccgagacctcagtttccccaaa ctcatcatgatcacagactacctgctgctttttcgtgtctatggcctggagagtctaaaa gacctcttccccaacctcacagtcatccgaggctcccgcctcttcttcaactatgccctg gtcatctttgagatggtccacctgaaggagctggggctctacaacctcatgaacatcacc cggggctctgtccgcattgagaagaataacgagctctgctacttggccactattgactgg tccaggatcctggattcagtggaggacaactacatcgtgctgaacaaagatgacaatgag gaatgtggtgatgtctgtccaggcactgccaagggcaagaccaattgccctgccaccgtc atcaatgggcagtttgtggaacggtgctggacacacagtcattgtcagaaagtttgcccg accatctgtaagtcacatggctgcacagctgaaggcctgtgctgccacaaggagtgctta ggcaactgttcggaacccgatgatccaaccaagtgtgtggcttgtcgcaacttctacctg gatggtcggtgtgtggagacctgcccacccccctactaccacttccaggattggcgatgt gtgaatttcagcttctgtcaagaccttcactacaaatgcaggaactctaggaagcctggc tgtcaccaatatgtcattcacaacaacaagtgcattcctgagtgtccttctggctatacc atgaattccagcaacttgatgtgtaccccatgtctgggaccctgtcctaaggtctgccag atcctggatggcgagaagactattgactctgtgacatctgcccaggagctccgaggctgc actgtgatcaatggcagcctcatcatcaacattcgagggggcaacaatctggcggctgag ctggaggctaaccttggcctcattgaagaaatttcagggttcctaaaaatccggcgttcc tatgctctagtatcgctttctttcttccggaagctccatctgattcgaggagagaccttg gaaatcgggaactattctttctacgccttggacaaccagaacctcaggcagctctgggac tggagcaaacacaacctcaccatcactcaaggcaagctcttcttccactacaaccccaaa ctctgcttgtcagaaattcacaagatggaagaagtttccggaactaagggccgccaggag agaaacgacattgccctgaagaccaatggggatcaggcatcctgtgaaaatgagttactt aaattttctttcattcggacatcttttgacaagatcttgctgaggtgggagccctactgg ccccctgacttccgagacctcctgggatttatgctcttctacaaagaggccccttatcag aatgtgacggaatttgatgggcaagatgcttgtggttccaacagctggactgtggtggat attgacccaccccaaaggtccaatgaccccaagtctcagaccccaagccaccctgggtgg ctaatgcgaggtctcaagccctggactcaatatgccatctttgtcaagaccttggttacc ttctctgatgaacgccggacctatggagccaaaagtgacatcatctatgtgcagacagat gccacaaatccttctgtccccctggaccccatatccgtttctaattcttcatctcagatt atcttaaagtggaagcccccctccgaccccaatggcaacatcacacactacctggtctac tgggagaggcaggcagaggacagtgagctgtttgagttggattattgtctcaaagggctg aagctcccctcacggacctggtctccaccttttgaatcggatgagtctcagaagcataat cagagcgagtatgacgactcggccagtgaatgctgctcatgccccaagactgactctcag atactgaaggagttggaggaatcctcattcaggaagaccttcgaggattacctgcataac gtggtgtttgtccccaggccatcccgaaaacgaagatcccttgaagaggtggggaatgtg acagccaccatgcctgcacttccagattttcccaacatctcctccaccgttgtgcccacg agtcaggaggagcacaggccatttgagaaagtggtgaacaaggagtcacttgtcatctct ggcctgagacactttactggctaccgcattgagctgcaagcctgcaaccaagattcccca gacgagaggtgcagtgttgctgcctacgtcagtgcccggaccatgcctgaagctaaggca gatgacatcgttggccctgtgacccatgaaatctttgagaacaatgtggtacacttgatg tggcaagagccaaaggagcctaatggtctgattgtgctgtatgaagtgagctaccggcgt tatggtgatgaggagctgcacctctgtgtctcccggaagcattttgccctggagcggggc tgcaggcttcgagggctctccccagggaactacagtgttcgagtccgggctacttccctg gcaggcaatggctcctggacagaacccacctatttttatgtgactgattatttagatgtc ccatcaaacattgccaaaattatcattgggcctctcatctttgtcttcctcttcagtgtt gtgattggaagtatttatctgttcctgagaaagaggcagccagatgggccaatgggacca ttgtatgcatcttcaaaccctgagtacctcagtgccagtgatgtgtttccttcttctgtg tacgtgccggatgagtgggaggtgcctcgagagaagatcaccctcctacgagagctgggg cagggatcctttggtatggtgtatgagggcaatgccaaggatatcatcaaaggcgaggca gagacccgagttgctgtgaagactgtcaatgagtcagccagtctccgagaacggatcgag ttcctcaacgaggcatcagtcatgaagggattcacctgccatcatgtggtccgcctcctt ggagtggtgtccaagggccagccaacactggtagtgatggaattgatggctcatggagac ctcaagagtcacctccgttctctgcgaccagatgctgagaataacccaggccgtcctcct cctaccttgcaagaaatgattcagatgacagcagaaattgctgatggcatggcatacttg aatgctaagaagtttgtgcaccgggacctggcagctcggaactgcatggttgctcatgat tttaccgtcaaaattggagactttggaatgacaagggatatctacgagacagattactat cggaaagggggcaagggcctgctgcctgtgcggtggatgtcacccgagtccctgaaggat ggagtctttactgcttcttctgatatgtggtcctttggtgtggtcctttgggaaatcacc agcctggctgaacagccttaccaaggcctgtcaaacgaacaggtgttgaaatttgtcatg gatggaggctatttggatccacctgataactgtccagagagactgactgacctgatgcgc atgtgctggcagttcaaccccaagatgaggccaaccttcctggaaattgtcaacctgctc aaggatgacctccaccctagctttccagaagtttccttcttctacagcgaagagaacaag gctcctgagagcgaggagctggagatggagttcgaggacatggagaatgtcccgttggat gggtcctctcactttcacagggaagaggctgggggccgggagggagggtcctctctgagc attaaacggacctatgacgaacacatcccatacacccacatgaacgggggcaagaagaat gggcgcgtgctcacactacccaggtccaacccttcctaa

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