Phocoena sinus (vaquita): 116751331 Help Entry 116751331         CDS       T07759                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism psiu  Phocoena sinus (vaquita) Pathway psiu04010   MAPK signaling pathway psiu04014   Ras signaling pathway psiu04015   Rap1 signaling pathway psiu04022   cGMP-PKG signaling pathway psiu04066   HIF-1 signaling pathway psiu04068   FoxO signaling pathway psiu04072   Phospholipase D signaling pathway psiu04150   mTOR signaling pathway psiu04151   PI3K-Akt signaling pathway psiu04152   AMPK signaling pathway psiu04211   Longevity regulating pathway psiu04213   Longevity regulating pathway - multiple species psiu04520   Adherens junction psiu04910   Insulin signaling pathway psiu04913   Ovarian steroidogenesis psiu04923   Regulation of lipolysis in adipocytes psiu04930   Type II diabetes mellitus psiu04931   Insulin resistance psiu04932   Non-alcoholic fatty liver disease psiu04960   Aldosterone-regulated sodium reabsorption psiu05010   Alzheimer disease psiu05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:psiu00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     116751331 (INSR)    04014 Ras signaling pathway     116751331 (INSR)    04015 Rap1 signaling pathway     116751331 (INSR)    04066 HIF-1 signaling pathway     116751331 (INSR)    04068 FoxO signaling pathway     116751331 (INSR)    04072 Phospholipase D signaling pathway     116751331 (INSR)    04022 cGMP-PKG signaling pathway     116751331 (INSR)    04151 PI3K-Akt signaling pathway     116751331 (INSR)    04152 AMPK signaling pathway     116751331 (INSR)    04150 mTOR signaling pathway     116751331 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     116751331 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     116751331 (INSR)    04923 Regulation of lipolysis in adipocytes     116751331 (INSR)    04913 Ovarian steroidogenesis     116751331 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     116751331 (INSR)   09149 Aging    04211 Longevity regulating pathway     116751331 (INSR)    04213 Longevity regulating pathway - multiple species     116751331 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     116751331 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     116751331 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     116751331 (INSR)    04932 Non-alcoholic fatty liver disease     116751331 (INSR)    04931 Insulin resistance     116751331 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:psiu01001]     116751331 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:psiu04090]     116751331 (INSR) Enzymes [BR:psiu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      116751331 (INSR) Protein kinases [BR:psiu01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    116751331 (INSR) CD molecules [BR:psiu04090]  Proteins   116751331 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 B2 Motif Other DBs NCBI-GeneID:  116751331 NCBI-ProteinID:  XP_032482990 Ensembl:  ENSPSNG00000007930 LinkDB All DBs Position 3:complement(5475213..5606645) Genome browser AA seq 1382 aa AA seqDB search MGAGGGRGAAAVPLLVAVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGAAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTVEGLCCHSECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC TIINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPMRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE RQEEDGELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQSEYEESAGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFIPRKSSSGPVAEDTRPSRKRRALGDVGNVTAAVPTIPGF PNTSSTSAPTSSEEHRPFEKVVNRESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYV SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGEEELHLCV SRRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG PLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR EKITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKG FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGFLDQPDN CPERVTDLMRMCWQFNPKMRPTFLEIVDLLKDELHPSFPEVSFFHSEENKVPESEELEME FEDMESVPLDRSSHVQREEAGGRDGGSALGLKRNYQEHIPYTHMNGGKKNGRILTLPRSN PS NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt atgggcgccgggggcgggcggggggcggcggccgtgccactgctggtggccgttgccgcg ctgctggtgggcgccgcgggccacctgtaccctggagaggtgtgccccggcatggatatc cggaataacctcacccggctgcacgagctggccaactgctcggtcatcgaaggacatttg cagatcttgttgatgttcaaaacgagacctgaggacttccgagacctcagtttccccaag ctcatcatgatcactgattacttgctgctcttccgggtctacgggctggagagcctgaag gacctgttccccaacctcacggtcatccggggctcccgcctcttctttaactacgcgctg gtcatcttcgagatggttcacctgaaggagcttggcctctacaacttgatgaacattacc cggggctccgttcgcatcgagaagaacaatgaactctgctacctggccactatcgactgg tctcgcatcctggattccgtggaggataattacatcgtgctgaacaaagacgacaatgag gagtgtggggacatttgtccaggcgctgcgaagggcaagaccaactgccctgccaccgtc atcaacgggcaatttgtggagcggtgttggacgcacagccactgccagaaagtgtgtccg accatctgtaagtctcacggctgcaccgttgagggtctctgttgccacagtgagtgcttg ggcaactgctctgagcctgacgaccccaccaagtgtgtggcctgtcgcaacttctacctg gatggcaggtgcgtggagacctgcccgcccccctactaccacttccaagactggcgctgt gtgaacttcagcttctgccaggacctgcacaacaaatgcaagaactctcggaggcagggc tgccaccagtatgtcattcacaataacaagtgcatccctgagtgcccctccgggtacacg atgaattccagcaacttgatgtgtactccatgcctgggcccctgtcccaaggtgtgccac ctcctggaaggcgagaagaccattgactcagtgacatctgcccaggagctccgaggctgc accatcattaacggaagcttaatcatcaacattcgagggggcaacaacctggcagctgag ctagaggccaaccttggactcattgaagaaatttcagggtatctgaaaatccgccgatca tatgccctggtgtcgctttccttcttccggaagttacgtctgattcgaggggagaccttg gaaatcgggaactactctttctatgccttggacaaccagaacctaaggcagctgtgggac tggagcaaacacaacctcaccatcactcaggggaaactcttcttccactataatcccaaa ctctgcttgtcagaaattcacaagatggaggaagtttcaggaacgaaggggcgccaggag agaaacgacattgccctgaagaccaatggggaccaggcgtcctgtgaaaatgaattactt aaattttcttacattcggacatcttatgacaagatcttgctgaaatgggagccgtattgg ccccccgacttccgagaccttctgggattcatgctcttctacaaagaggccccttatcag aacgtgacggaatttgatgggcaggatgcatgcggctccaacagctggaccgtggtggat atcgacccgcctatgaggtccaacgaccccaagtcgcagaaccaccccgggtggctaatg cgcggtctcaagccctggacccagtacgccatctttgtcaagaccttggtcaccttttct gatgaacgccgcacatatggggccaagagcgacatcatctatgtccagacagatgccact aatccttctgtccccctggatcccatctcggtgtctaattcttcgtcccagattattctg aagtggaagcctccctctgaccccaatggcaacatcacacactacttggtattctgggag agacaggaggaagacggtgagctgtatgaattagattactgcctcaaagggttgaagctg ccctcccggacctggtctccgccgttcgagtctgaggggtcccagaagcacaatcagagt gagtacgaagagtctgccggtgaatgctgttcctgcccgaagaccgactctcagatcctc aaggagttggaggagtcctcattcaggaaaacattcgaagattacctgcacaatgtcgtc ttcatccccagaaaatcctcttcaggccctgttgccgaggacactaggccgtcgaggaaa cgcagggcccttggtgatgtggggaatgtgacagcggccgtgcccaccattccgggattc cccaatacgtcctcaaccagcgcacctacgagctcagaggagcacagaccgttcgagaaa gtggtgaacagggagtctctggtcatctctggcctgcgtcactttactggctatcgcatt gagctgcaggcttgcaaccaagattcccccgaggagaggtgcagtgtggctgcatatgtc agtgccaggaccatgcccgaagccaaggcagatgatattgttggccccgtgacccacgaa atcttcgagaacaacgtcgttcacctgatgtggcaggagcccaaggaacccaacggtctg atcgtgctgtacgaagtgagttatcgacgatacggcgaagaggagctgcatctctgcgtc tcccgcaggcattttgctctggagcggggctgcaggctgcgtggtctgccacccgggaac tacagtgtgcgagttcgggccacctccctggcgggcaatggctcctggacggaagctacc tatttctacgtcacagactatttagacgtgccatcaaatattgcaaaaattatcatcggc cccctcatctttgtctttctcttcagtgtcgtgatcggaagtatttatctattcctgaga aagaggcagccggatgggccactgggaccactgtatgcttcttcaaaccccgagtacctc agtgccagcgatgtgtttccctgctctgtgtacgtgccggatgagtgggaggtgcctcga gagaagatcacgctcctgcgagaactggggcagggctccttcggcatggtgtacgagggc aacgccagggacattgtcaagggcgaggcggagacccgagtggcggtgaagacggtgaac gagtctgccagcctgcgagagcggatcgaatttctcaacgaggcctcagtcatgaagggc ttcacctgccaccacgtggttcgcctcctgggggtggtatccaaaggccagccgacgctg gtggtgatggagttgatggctcatggggacttgaagagctacctccgttccctgcggcct gaggccgagaataaccccggccgccctccccctaccctgcaagagatgattcagatggct gcggagatcgccgacgggatggcatacctgaacgccaagaagttcgtacaccgggacctc gcagctcgaaactgcatggtcgcccacgattttaccgtcaaaattggagactttggaatg accagagacatctacgaaacggattactaccggaaagggggaaagggtctgctccccgtg cggtggatggcacccgaatcgctgaaggacggggtctttaccacttcttcggacatgtgg tcctttggcgtggtcctttgggaaattaccagcttggcagaacagccttaccaaggccta tcaaacgagcaggtgttaaaatttgtcatggatggagggtttctggatcaacccgacaac tgtcctgagagagtcaccgacctgatgcgcatgtgttggcagttcaaccccaagatgcgg ccgaccttcctggaaattgtcgacctgctcaaggacgagctgcaccccagttttcccgaa gtttccttcttccacagcgaggagaacaaggtgcccgagagcgaggagctggagatggaa tttgaggacatggagagtgtccccctggaccggtcctcacatgtgcagagggaggaggcc gggggccgggatggagggtccgcactggggctaaagagaaactatcaggaacacatcccc tacacccacatgaacgggggcaagaaaaacggacgcattctgactctgccccggtctaat ccttcctaa

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