Pan troglodytes (chimpanzee): 459388
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Entry
459388 CDS
T01005
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr04137
Mitophagy - animal
ptr04140
Autophagy - animal
ptr04141
Protein processing in endoplasmic reticulum
ptr04210
Apoptosis
ptr04932
Non-alcoholic fatty liver disease
ptr05010
Alzheimer disease
ptr05012
Parkinson disease
ptr05014
Amyotrophic lateral sclerosis
ptr05020
Prion disease
ptr05022
Pathways of neurodegeneration - multiple diseases
ptr05160
Hepatitis C
ptr05162
Measles
ptr05168
Herpes simplex virus 1 infection
ptr05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
459388 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
459388 (EIF2AK3)
04137 Mitophagy - animal
459388 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
459388 (EIF2AK3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
459388 (EIF2AK3)
05162 Measles
459388 (EIF2AK3)
05168 Herpes simplex virus 1 infection
459388 (EIF2AK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
459388 (EIF2AK3)
05012 Parkinson disease
459388 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
459388 (EIF2AK3)
05020 Prion disease
459388 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
459388 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
459388 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
459388 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptr01001
]
459388 (EIF2AK3)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
459388 (EIF2AK3)
Protein kinases [BR:
ptr01001
]
Serine/threonine kinases: Other
PEK family [OT]
459388 (EIF2AK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
Kdo
ABC1
OATP
Motif
Other DBs
NCBI-GeneID:
459388
NCBI-ProteinID:
XP_001140984
Ensembl:
ENSPTRG00000012173
VGNC:
237
UniProt:
H2QIB3
LinkDB
All DBs
Position
2A:complement(87804753..87876762)
Genome browser
AA seq
1115 aa
AA seq
DB search
MERAISPGLLVRALLLLLLLLGLAARTVAAGRARGLPAPTAEAAFGLGAAAAPTSATRVP
AAGAVAAAEVTVEDAEALPAAAGEQEPRGPEPDDETELQPRGRSLVIISTLDGRIAALDP
ENHGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGDLFQWDRDRESMETVPFTVES
LLESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDSDEMEQEEDILLLQR
TQKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTFKPNENTEESKIISDVEE
QEAAIMDIVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLLKDGKVIPISLFDDTS
YTSNDDVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPSSPKALESVNEN
AIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYY
LPYYKRERNKRSTQITVRFLDNPHYNKNIRKKDPVLLLHWWKEIVATILFCIIATTFIVR
RLFHPHPHRQRKESETQCQTENKYDSVSGEANDSSWNDIKNSGYISRYLTDFEPIQCLGR
GGFGVVFEAKNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLEA
PPEKWQEKMDEIWLKDESTDWPLSSPSPMDAPSVKIRRMDPFSTKEHIEIIAPSPQRSRS
FSVGISCDQTSSSESQFSPLEFSGMDHEDISESVDAAYNLQDSCLTDCDVEDGTMDGNDE
GPSFELCPSEASPYVRSRERTSSSIVFEDSGCDNASSKEEPKTNRLHIGNHCANKLTAFK
PTSSKSSSEATLSISPPRPTTLSLDLTKNTTEKLQPSSPKVYLYIQMQLCRKENLKDWMN
GRCTIEERERSMCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTA
MDQDEEEQTVLTPMPAYARHTGQVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYPF
STQMERVRTLTDVRNLKFPPLFTQKYPCEYVMVQDMLSPSPMERPEAINIIENAVFEDLD
FPGKTVLRQRSRSLSSSGTKHSRQSNNSHSPLPSN
NT seq
3348 nt
NT seq
+upstream
nt +downstream
nt
atggagcgcgccatcagcccggggctgctggtacgggcgctgctgctgctgctgctgctg
ctggggctcgcggcaaggacggtggccgcggggcgcgcccgtggcctcccagcgccgacg
gcggaggcggcgttcggcctcggggcggccgctgctcccacctcagcgacgcgagtaccg
gcggcgggcgccgtggctgcggccgaggtgactgtggaggacgctgaggcgctgccggca
gccgcgggagagcaggagcctcggggtccggaaccagacgatgagacagagttgcaaccg
cgcggcaggtcattagtaattatcagcactttagatgggagaattgctgccttggatcct
gaaaatcatggtaaaaagcagtgggatttggatgtgggatctggttccttggtgtcatcc
agccttagcaaaccagaggtatttgggaataagatgatcattccttccctggatggagac
ctcttccagtgggaccgagaccgtgagagcatggaaacagttcctttcacagttgaatca
cttcttgaatcttcttataaatttggagatgatgttgttttggttggaggaaaatctctg
actacatatggactcagtgcatatagtggaaaggtgaggtatatctgttcagctctgggt
tgtcgccaatgggatagtgacgaaatggaacaagaggaagacatcctgcttctacagcgt
acccaaaaaactgttagagctgtcggacctcgcagtggcaatgagaagtggaatttcagt
gttggccactttgaacttcggtatattccagacatggaaacgagagcaggatttattgaa
agcacctttaagcccaatgagaacacagaagagtctaaaattatttcagatgtggaagaa
caggaagctgccataatggacatagtgataaaggtttcggttgctgactggaaagttatg
gcattcagtaagaagggaggacatctggaatgggagtaccagttttgtactccaattgca
tctgcctggttacttaaggatgggaaggtcattcccatcagtctttttgatgatacaagt
tatacatctaatgatgatgttttagaagatgaagaagacattgtagaagctgccagagga
gccacagaaaacagtgtttacttgggaatgtatagaggccagctgtatctgcagtcatca
gtcagaatttcagaaaagtttccttcaagtcccaaggctttggaatctgtcaatgaaaac
gcaattattcctttgccaacaatcaaatggaaacccttaattcattctccttccagaact
cctgtcttggtaggatctgatgaatttgacaaatgtctcagtaatgataagttttctcat
gaagaatatagtaatggtgcactttcaatcttgcagtatccatatgataatggttattat
ctaccatactacaagagggaaaggaacaaacgaagcacacagattacagtcagattcctc
gacaacccacattacaacaagaatatccgcaaaaaggatcctgttcttcttttacactgg
tggaaagaaatagttgcaacgattttgttttgtatcatagcaacaacgtttattgtgcgc
aggcttttccatcctcatcctcacaggcaaaggaaggagtctgaaactcagtgtcaaact
gaaaataaatatgattccgtaagtggtgaagccaatgacagtagctggaatgacataaaa
aactctggatatatatcacgatatctaactgattttgagccaattcaatgcctgggacgt
ggtggctttggagttgtttttgaagctaaaaacaaagtagatgactgcaattatgctatc
aagaggatccgtctccccaatagggaattggctcgggaaaaggtaatgcgagaagttaaa
gccttagccaagcttgaacacccgggcattgttagatatttcaatgcctggctcgaagca
ccaccagagaagtggcaagaaaagatggatgaaatttggctgaaagatgaaagcacagac
tggccactcagctctcctagcccaatggatgcaccatcagttaaaatacgcagaatggat
cctttctctacaaaagaacatattgaaatcatagctccttcaccacaaagaagcaggtct
ttttcagtagggatttcctgtgaccagacaagttcatctgagagccagttctcaccactg
gaattctcaggaatggaccatgaggacatcagtgagtcagtggatgcagcatacaacctc
caggacagttgccttacagactgtgatgtggaagatgggactatggatggcaatgatgag
gggccctcctttgaactttgtccttctgaagcttctccttatgtaaggtcaagggagaga
acctcctcttcaatagtatttgaagattctggctgtgataatgcttccagtaaagaagag
ccgaaaactaatcgattgcatattggcaaccattgtgctaataaactaactgctttcaag
cccaccagtagcaaatcttcttctgaagctacattgtctatttctcctccgagaccaacc
actttaagtttagatctcactaaaaacaccacagaaaaactccagcccagttcaccaaag
gtgtatctttacattcaaatgcagctgtgcagaaaagaaaacctcaaagactggatgaat
ggacgatgtaccatagaggagagagagaggagcatgtgtctgcacatcttcctgcagatc
gcagaggcagtggagtttcttcacagtaaaggactgatgcacagggacctcaagccatcc
aacatattctttacaatggatgatgtggtcaaggttggagactttgggttagtgactgca
atggaccaggatgaggaagagcagacggttctgaccccaatgccagcttatgccagacac
acaggacaagtagggaccaaactgtatatgagcccagagcagattcatggaaacagctat
tctcataaagtggacatcttttctttaggcctgattctatttgaattgctgtatccattc
agcactcagatggagagagtcaggaccttaactgatgtaagaaatctcaaatttccacca
ttatttactcagaaatatccttgtgagtatgtgatggttcaagacatgctctctccatcc
cccatggaacgacctgaagctataaacatcattgaaaatgctgtatttgaggacttggac
tttccaggaaaaacagtgctcagacagaggtctcgctccttgagttcatcgggaacaaaa
cattcaagacagtccaacaactcccatagccctttgccaagcaattag
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