Saccharomyces cerevisiae (budding yeast): YGR144W
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Entry
YGR144W CDS
T00005
Symbol
THI4, ESP35, MOL1
Name
(RefSeq) thiamine thiazole synthase
KO
K03146
cysteine-dependent adenosine diphosphate thiazole synthase [EC:
2.4.2.60
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce00730
Thiamine metabolism
sce01100
Metabolic pathways
sce01240
Biosynthesis of cofactors
Module
sce_M00898
Thiamine biosynthesis, pyridoxal-5P => TMP/thiamine/TPP
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00730 Thiamine metabolism
YGR144W (THI4)
Enzymes [BR:
sce01000
]
2. Transferases
2.4 Glycosyltransferases
2.4.2 Pentosyltransferases
2.4.2.60 cysteine-dependent adenosine diphosphate thiazole synthase
YGR144W (THI4)
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Motif
Pfam:
Thi4
DAO
NAD_binding_8
Lycopene_cycl
FAD_binding_2
FAD_oxidored
NAD_binding_9
Pyr_redox_2
HI0933_like
Pyr_redox_3
GIDA
Trp_halogenase
Motif
Other DBs
NCBI-GeneID:
853047
NCBI-ProteinID:
NP_011660
SGD:
S000003376
UniProt:
P32318
Structure
PDB
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Position
VII:780399..781379
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AA seq
326 aa
AA seq
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MSATSTATSTSASQLHLNSTPVTHCLSDIVKKEDWSDFKFAPIRESTVSRAMTSRYFKDL
DKFAVSDVIIVGAGSSGLSAAYVIAKNRPDLKVCIIESSVAPGGGSWLGGQLFSAMVMRK
PAHLFLQELEIPYEDEGDYVVVKHAALFISTVLSKVLQLPNVKLFNATCVEDLVTRPPTE
KGEVTVAGVVTNWTLVTQAHGTQCCMDPNVIELAGYKNDGTRDLSQKHGVILSTTGHDGP
FGAFCAKRIVDIDQNQKLGGMKGLDMNHAEHDVVIHSGAYAGVDNMYFAGMEVAELDGLN
RMGPTFGAMALSGVHAAEQILKHFAA
NT seq
981 nt
NT seq
+upstream
nt +downstream
nt
atgtctgctacctctactgctacttccacaagtgcctctcaattgcacttaaactctact
ccagttactcactgcttatctgacatcgttaagaaagaagattggtctgactttaaattt
gctcccatccgcgaatccactgtctctcgtgctatgacttctcgttatttcaaggatctt
gacaagtttgccgtttctgacgtgattattgtcggtgcgggctcttcaggtttatccgcc
gcttacgtcatcgccaagaacagaccagacttgaaggtttgtattatcgaaagttcagtt
gcaccaggtggtggtagttggttgggtggtcaattatttagtgccatggttatgagaaaa
ccagctcatttgttcttacaagagttggaaatcccttacgaagacgaaggtgactatgtt
gtcgttaagcatgccgctttgttcatctctactgtcctttcaaaggtcttgcaattacca
aatgttaaactgttcaatgctacctgtgttgaagatttggttaccagaccacctaccgaa
aagggcgaagtcaccgttgctggtgttgtcaccaactggacgttagttacccaagctcac
ggtactcaatgttgcatggaccctaacgtaattgaattggcaggttacaaaaatgacgga
actcgtgacttgagtcaaaagcatggtgtcattttatccactaccggtcatgatggtcca
tttggtgctttctgcgccaagagaatcgtcgacattgatcaaaaccaaaaattgggcggt
atgaagggtctggacatgaaccatgccgaacacgatgtcgttattcactctggtgcatac
gccggtgttgacaacatgtactttgctggtatggaagttgctgaactggatggattaaac
cgtatgggtccaacttttggagctatggctttgagtggtgttcatgctgctgagcaaatt
ttgaaacactttgctgcttag
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