KEGG   Staphylococcus haemolyticus Sh29/312/L2: ShL2_01296
Entry
ShL2_01296        CDS       T03837                                 
Symbol
dfrA_1
Name
(GenBank) trimethoprim-sensitive dihydrofolate reductase
  KO
K18591  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
shh  Staphylococcus haemolyticus Sh29/312/L2
Pathway
shh00670  One carbon pool by folate
shh00790  Folate biosynthesis
shh01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:shh00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    ShL2_01296 (dfrA_1)
   00670 One carbon pool by folate
    ShL2_01296 (dfrA_1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:shh01504]
    ShL2_01296 (dfrA_1)
Enzymes [BR:shh01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     ShL2_01296 (dfrA_1)
Antimicrobial resistance genes [BR:shh01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    ShL2_01296 (dfrA_1)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AKC76159
UniProt: A0A7Z1N3T2
LinkDB
Position
1363522..1364019
AA seq 165 aa
MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILGRKNLESIGRALPDRRN
IILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIYNLFFPYVEKMYITKIHHE
FEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYERKNLLS
NT seq 498 nt   +upstreamnt  +downstreamnt
atgaaagtttctttgattgctgcgatggataagaatagagtgattggcaaagagaatgac
attccttggaggattcccaaggactgggaatatgttaaaaatactacaaagggacatccg
ataatattaggtaggaagaaccttgaatcaatcggaagagccttacctgacagaagaaat
attattctgacgagagataaggggtttacctttaatggttgtgaaattgttcattcaata
gaagatgtttttgagttatgtaaaaacgaagaagaaatttttattttcggaggagaacag
atttataatttgtttttcccttatgttgagaaaatgtacatcacaaaaatacatcatgaa
ttcgaaggagatactttttttccagaagtgaattatgaggaatggaatgaggtatttgcc
caaaaagggataaagaatgataaaaatccgtataactactattttcatgtatatgaaaga
aaaaacttattgagttaa

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