Sarcophilus harrisii (Tasmanian devil): 100933073
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Entry
100933073 CDS
T02286
Name
(RefSeq) arachidonate 12-lipoxygenase, 12S-type isoform X1
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr00590
Arachidonic acid metabolism
shr01100
Metabolic pathways
shr01523
Antifolate resistance
shr04726
Serotonergic synapse
shr04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
100933073
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
100933073
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100933073
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100933073
Enzymes [BR:
shr01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
100933073
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Gene cluster
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
DUF3575
Motif
Other DBs
NCBI-GeneID:
100933073
NCBI-ProteinID:
XP_031821253
Ensembl:
ENSSHAG00000000343
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All DBs
Position
4:289050151..289064620
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AA seq
665 aa
AA seq
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MGRYRVRVATGNSAFSGSNNQVQLWLVGLRAEVELGLRLRPARGQMEDFEVDVSEDLGPL
QFVKLRKIHLLIKDAWFCNHITVWVFEQSMEEKEIVFPCYRWVEGDGIICLPETTAWMIR
NESQGLFQKHQEEELKARRTLYGWVSWKKGIPLSVAAASEKDLPLDARFHEEKKVDFERT
RVVGVTEIALKRLYTLLSSWNSLEDFDQIFWGGKSALAKRVRLSWKDDDFFGYQFLNGVN
PTLLRKSSSLPTRLVIPPGTEDLKAQLERKLQEGCLFEVDFSLLAGIQANVIQGERQHLA
APLLMLKMEPDGKLLPMVIQLQLPGSDSPVPPLFLPSDPSLTWLLAKAWVKNSDFQLHEL
QAHLLKTHLMAEVFAVATMRCLPGMHPIFKLLIPHLRYTLEINTRARTKLISNGGFFDQA
VNTGGGGHLDVLRRATTCLTYRSLCPPDDLADRGLLGVPSAFYAHDAVRLWDIISRYVQG
IVQLHYLEDEVVRSDPELQAWCREITEIGLCKAQERGFPVSFQSRDELCHFVTMCIFTCT
AQHSAVNQGQLDWYTWVPNAPCTMRQPPPTTKDVTLEMVMATMPNVHQACIQMTISWHLG
RFQPDMVPLGHHKEQYFSGPGPQAVLNRFQEDLYTLEREIVARNESLDLPYEYLKPSRIE
NSITI
NT seq
1998 nt
NT seq
+upstream
nt +downstream
nt
atgggtcgctaccgggtccgagtggccactggaaactctgctttctcagggtccaacaac
caggtgcagctgtggttggtagggctccgtgcagaggtggaactggggcttcggctacgg
ccagctcgaggacagatggaggattttgaagttgatgtctcagaagacctgggtcccctc
cagtttgtgaagcttcgtaaaattcatcttctgataaaggatgcatggttctgcaaccat
ataactgtttgggtctttgaacagagcatggaagagaaggaaatagtattcccctgttac
cgctgggtagaaggggatggtatcatctgccttcctgagaccactgcttggatgataaga
aatgaatcccaaggcctgtttcaaaaacatcaagaagaagagctgaaggcgagaaggaca
ctctatggctgggtcagctggaagaaagggataccattgtcagtggctgcagcatcagag
aaagacctgcccctggatgcaagattccatgaggagaagaaggttgacttcgaaaggaca
cgggttgtgggggtgacagaaattgcccttaaacgtctgtacaccctcctgagctcctgg
aatagcttggaagattttgaccaaatcttctggggtggcaagagtgccctggccaagagg
gtgcgcctatcctggaaagatgatgatttttttggctaccagttcctcaatggtgtcaat
cccacactgctgagaaaatcctcttcactccccactcgactcgtgattcccccagggaca
gaggatcttaaggcccaactggaaagaaagctccaggagggttgcctctttgaagttgac
ttttcactgttagctggaatccaggccaatgtgatccagggagagaggcaacatctggct
gctcccctacttatgttaaagatggagcctgatgggaagctgctccccatggtcatccag
ctccaacttcccggctctgactctccagttccaccactcttcctgccttcagatccctcc
ctcacttggcttttggccaaggcttgggtcaaaaattctgacttccagctgcatgaactg
caagcacatctgttgaagacgcatttgatggctgaagtgtttgctgtagccaccatgagg
tgcctcccagggatgcaccccatctttaagctcctgatacctcacctccgttatacactg
gagattaacactcgtgccaggaccaagctcatctctaatgggggattttttgatcaggcg
gtgaatactggtgggggaggtcacctggatgtcctccgaagggcaacaacttgtctgacc
tatagatccctctgccctcctgatgacctggctgaccgagggcttctgggggtcccatca
gctttctatgctcatgatgccgttcggctctgggacattatctcccgatacgtgcaagga
atagtccagctccattatctggaagacgaggttgtgcggagtgaccctgagctacaggct
tggtgccgagagatcactgagattgggctgtgtaaggcgcaggaacgagggtttcctgta
tctttccagtctcgtgatgagctttgccattttgtcaccatgtgcatctttacatgcaca
gctcaacattctgccgttaatcaaggacagctagactggtatacctgggtccctaatgct
ccatgcactatgaggcagccaccaccaactacaaaggatgtaacattagagatggtgatg
gccacaatgcccaatgtccatcaagcctgtatccagatgactatttcgtggcacttgggt
cggttccagccagacatggtacccctgggtcatcacaaagagcaatacttctcaggacct
gggccccaagctgtactaaatcgtttccaggaagatttatatactctagaaagggagatt
gtggctcgtaatgaaagtttggacctgccttatgaataccttaagccaagccggatagaa
aacagtattactatctaa
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