Trachypithecus francoisi (Francois's langur): 117095719
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Entry
117095719 CDS
T07225
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
tfn
Trachypithecus francoisi (Francois's langur)
Pathway
tfn00230
Purine metabolism
tfn00670
One carbon pool by folate
tfn01100
Metabolic pathways
tfn01523
Antifolate resistance
Module
tfn_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tfn00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
117095719 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
117095719 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
117095719 (GART)
Enzymes [BR:
tfn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
117095719 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
117095719 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
117095719 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
CPSase_L_D2
ATP-grasp
ATP-grasp_2
ATP-grasp_4
ATP-grasp_3
Dala_Dala_lig_C
Sacchrp_dh_NADP
RimK
LUD_dom
Motif
Other DBs
NCBI-GeneID:
117095719
NCBI-ProteinID:
XP_033088264
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAAQVLIIGSGGREHTLAWKLAQSHHVRQVLVAPGNAGTACSEKISNTAISISDHTALAQ
FCKEEKIEFVVVGPEAPLAAGIVGNLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHRIP
TAQWKAFTKPEEACSFIMSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
GAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
QVSNDLLLKIKDTVLQRTVDGMRQEGTPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFSEA
QALGLEVFHAGTALKNGKIVTHGGRVLAVTAIRENLNSALEEAKKGLAAIKFEGAIYRKD
IGFRAIAFLQQPRGLTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGVFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDVVVGIASSGLHSNGFSLVRKIVTKSSLQYSSPAPDGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPKVFSWLQQEG
HLSEEEMARTFNCGVGAALVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGSPRVKVKN
LIESMQINGSVLKNGSLKNHFSFGKKKARVAVLISGTGSNLQALIDSTREPNSSAQIDVV
ISNKAAVAGLDKAKRAGIPTRVINHKLYKNRVEFDNAIDLVLEEFSIDIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQALETGVTITGCTVHFVTEDVDAGQIILQEA
VPVKRGDTVATLSERVKLAEHKTFPAALQLVASGTVQLGENGKICWVKEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccaagtacttataattggcagtggaggaagggaacatacgctggcctggaaa
cttgcacagtctcatcatgtcagacaagtgttggttgccccaggaaatgcaggcactgcc
tgctctgaaaagatttcaaataccgccatctcaatcagtgaccacactgcccttgctcaa
ttctgcaaagaggagaaaattgaattcgtggttgttggaccagaagcacctctggctgct
gggattgttgggaacctgacgtctgcaggagtgcgatgctttggcccaacagcggaagcg
gctcagttagagtccagcaaaaggtttgccaaagagtttatggacagacatagaatccca
actgctcaatggaaggctttcaccaaacctgaagaggcctgcagcttcattatgagtgca
gacttccctgctttggttgtgaaggccagtggtcttgcagctggaaaaggggtgattgtt
gcaaagagcaaagaagaggcctgcaaagctgtacaagagatcatgcaggagaaagccttt
ggggcagctggagaaacaattgtcattgaagaacttcttgatggagaagaggtgtcttgt
ctgtgcttcactgatggcaagactgtggcccccatgcccccggcacaggaccataagcga
ttactggagggagatggcggccctaacacagggggaatgggagcctattgtccggcccct
caggtttctaatgatctattactaaaaattaaagatactgttcttcagaggacagtggat
ggcatgcggcaagagggtactccatatacaggtattctctatgctggaataatgctgacc
aaggatggcccaaaagttctagagtttaattgccgttttggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgatctttatgaagtgattcagtccaccttagatggactg
ctctgcacatctctgcctgtttggctagaaaaccacaccgccctaactgttgtcatggca
agtaaaggttatcctggagactacaccaagggtgtagagataacagggttttctgaggct
caagctctaggactggaggtgttccacgcaggcactgcccttaaaaatggcaaaatagta
actcatgggggtagagttcttgcagtcacagccatccgggaaaatctcaattcagctctc
gaggaagccaagaaaggactagcggctataaagtttgagggagcaatttataggaaagac
atcggctttcgtgccatagctttcctccagcagcccaggggtttgacttacaaggaatct
ggagtagacattgcagctggaaatatgctggtcaagaaaattcagcctttagcaaaagcc
acttccagatcaggctgtaaagttgatcttggaggttttgctggtgtttttgatttaaaa
gcagctggtttcaaagatccccttctggcctctggaacagatggcgttggaactaaacta
aagattgcccagctgtgcaacaaacatgataccattggtcaagatttggtagcaatgtgt
gttaatgatattctggcacaaggagcagagcccctcttcttccttgattacttttcctgt
ggaaaacttgacctcagtgtaactgaagccgttgttgctggaattgctaaagcttgtgga
aaagctggatgtgctcttcttggaggtgaaacagcagaaatgcctgacatgtatccccct
ggagagtatgacctagctgggtttgccgttggtgccatggagcgagatcagaaactccct
cacctggaaagaatcaccgagggtgatgttgttgttggaatagcttcatctggtcttcat
agcaatggatttagccttgtgaggaagatcgtgacaaaatcttccctccagtactcctct
ccagcacctgatggttgtggtgaccagactttaggggacttacttctcacgccaaccaga
atctacagccattcactgttacctgtcctacgttcaggacatgtcaaagcctttgcccat
attactggtggaggattactagagaacatccccagagtcctccctgagaaacttggggta
gatttagatgcccagacctggaggatccccaaggtcttctcatggttacagcaggaagga
cacctctctgaggaagagatggccagaacatttaactgtggggttggcgctgcccttgtg
gtatcaaaggagcagacagagcagattctgagggatatccagcagcacaaggaagaagcc
tgggtgattggcagtgtggttgcacgagctgaaggttccccacgtgtgaaagtcaagaat
ctgattgaaagcatgcaaataaatgggtcagtgttgaagaatggctccctgaaaaatcat
ttctcttttggaaaaaaaaaggccagagtggctgtcttaatatctggaacaggatcgaac
ctgcaagcactcatagacagtactcgggaaccaaatagctctgcacaaattgatgttgtt
atctccaacaaagccgcagtagctgggttagataaagcgaaaagagctggtattcccact
agagtaattaatcataaactgtataaaaatcgtgtagaatttgacaatgcaattgaccta
gtccttgaagagttctccatagacatagtctgtcttgcaggattcatgagaattctttct
ggcccctttgtccgaaagtggaatggaaaaatgctcaatatccacccatccttgctccct
tcttttaagggttcgaatgcccatgagcaagccctggaaaccggagtcacaattactggg
tgcactgtacactttgtaactgaagatgtagatgctggacaaattattttgcaagaagct
gttcccgtgaagaggggtgatactgttgcaactctttctgaaagagtaaaattagcagaa
cataaaacatttcctgcagccctccagttggtggccagtggaactgtacagcttggagaa
aatggcaagatctgttgggttaaagaggaatga
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