KEGG   Vulpes lagopus (Arctic fox): 121490703
Entry
121490703         CDS       T07435                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
vlg  Vulpes lagopus (Arctic fox)
Pathway
vlg01522  Endocrine resistance
vlg04110  Cell cycle
vlg04115  p53 signaling pathway
vlg04151  PI3K-Akt signaling pathway
vlg04218  Cellular senescence
vlg04530  Tight junction
vlg04660  T cell receptor signaling pathway
vlg04933  AGE-RAGE signaling pathway in diabetic complications
vlg04934  Cushing syndrome
vlg05160  Hepatitis C
vlg05162  Measles
vlg05163  Human cytomegalovirus infection
vlg05164  Influenza A
vlg05165  Human papillomavirus infection
vlg05166  Human T-cell leukemia virus 1 infection
vlg05167  Kaposi sarcoma-associated herpesvirus infection
vlg05169  Epstein-Barr virus infection
vlg05200  Pathways in cancer
vlg05203  Viral carcinogenesis
vlg05212  Pancreatic cancer
vlg05214  Glioma
vlg05218  Melanoma
vlg05219  Bladder cancer
vlg05220  Chronic myeloid leukemia
vlg05222  Small cell lung cancer
vlg05223  Non-small cell lung cancer
vlg05224  Breast cancer
vlg05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:vlg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    121490703 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    121490703 (CDK4)
   04115 p53 signaling pathway
    121490703 (CDK4)
   04218 Cellular senescence
    121490703 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    121490703 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    121490703 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    121490703 (CDK4)
   05203 Viral carcinogenesis
    121490703 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    121490703 (CDK4)
   05225 Hepatocellular carcinoma
    121490703 (CDK4)
   05214 Glioma
    121490703 (CDK4)
   05220 Chronic myeloid leukemia
    121490703 (CDK4)
   05218 Melanoma
    121490703 (CDK4)
   05219 Bladder cancer
    121490703 (CDK4)
   05224 Breast cancer
    121490703 (CDK4)
   05222 Small cell lung cancer
    121490703 (CDK4)
   05223 Non-small cell lung cancer
    121490703 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    121490703 (CDK4)
   05160 Hepatitis C
    121490703 (CDK4)
   05164 Influenza A
    121490703 (CDK4)
   05162 Measles
    121490703 (CDK4)
   05163 Human cytomegalovirus infection
    121490703 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    121490703 (CDK4)
   05169 Epstein-Barr virus infection
    121490703 (CDK4)
   05165 Human papillomavirus infection
    121490703 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    121490703 (CDK4)
   04934 Cushing syndrome
    121490703 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    121490703 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:vlg01001]
    121490703 (CDK4)
Enzymes [BR:vlg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     121490703 (CDK4)
Protein kinases [BR:vlg01001]
 Serine/threonine kinases: CMGC group
  CDK family
   121490703 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 121490703
NCBI-ProteinID: XP_041610559
LinkDB
Position
5:67803344..67806285
AA seq 303 aa
MATPRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPRPVQTVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLQKAEG
NPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggctactcctcggtacgagccagtggctgagattggggttggtgcctatggaacggtg
tacaaggcccgtgatccgcacagcggccacttcgtggccctcaagagcgttagagtccct
aatggaggaggtgccggagggggccttcccatcagcacagttcgtgaagtggcattgctg
aggcggctggaggcttttgagcatcccaacgttgtccggctgatggacgtctgcgccact
gcccgaaccgaccgggagaccaaagtgaccctggtgtttgagcacgtggaccaagacctg
agaacgtacctggacaaggcacccccaccgggcttgccagtggagaccatcaaggacctg
atgcgccagtttctaagaggcctagatttccttcatgccaactgcatcgttcaccgagac
ctgaagcccgagaacattctggtgaccagtggtgggacagtcaagctggctgattttggt
ctggccagaatctacagctaccagatggcacttacgcctgtggttgttacactctggtat
cgtgctccagaagttcttctgcagtctacatatgcaacacccgtggacatgtggagtgtc
ggctgtatcttcgcagagatgtttcgtcgcaagcctctcttctgtggaaactctgaagct
gaccagttaggcaaaatctttgacctgatcgggctgcccccagaggatgactggccccga
gatgtgtctctgccccgaggagccttttcccctagagggccccgtccagtacagacagtg
gtacctgagatggaggagtctggagcacagctgctgctggagatgctgacttttaaccca
cacaagcgaatctctgccttccgagccctgcagcactcttatctacaaaaggcagaaggt
aacccagagtga

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