Vicugna pacos (alpaca): 102541386
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Entry
102541386 CDS
T08098
Symbol
HSD17B2
Name
(RefSeq) estradiol 17-beta-dehydrogenase 2 isoform X1
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc00140
Steroid hormone biosynthesis
vpc01100
Metabolic pathways
vpc04913
Ovarian steroidogenesis
Module
vpc_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
102541386 (HSD17B2)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
102541386 (HSD17B2)
Enzymes [BR:
vpc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
102541386 (HSD17B2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
102541386 (HSD17B2)
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Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Epimerase
Motif
Other DBs
NCBI-GeneID:
102541386
NCBI-ProteinID:
XP_006207586
UniProt:
A0A6I9IDF9
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All DBs
Position
9
AA seq
388 aa
AA seq
DB search
MGTFLSETAWLCLAVTAVLGGTILWRLNKSQGQVGKKVVCLAGLWGGACLLSLSLSWGLL
LFSFSCFIMYTYFSGQEFLPVDQKAILITGSDSGFGHALSKYLDKLGFTVFAGVLNEEGP
GAEELRRTCSTRLSVLQLDITKPQQIKDAHSKVMEKVQNRGLWAVVNNAGIFSYPVDGEL
TPMTEYKRCMAVNFFGTVEVTKAFLPLLRKSKGRLVNISSLAGAIPMERLAAYSSSKAAL
TMFSAVLRQELSNWGVKVSVIQPGGFQTNIAGTSDMWDKLEKSILDHLPTDVQEDYGQDY
IHRQRNYLRLINNFSDPNISPVLLDIHHAISAKSPCAFYAPGKMTYPWIYFVSFSPTGIF
DYFAKKNHGHGRIMPRALSKPNGKNEAI
NT seq
1167 nt
NT seq
+upstream
nt +downstream
nt
atggggactttcctctctgagacggcgtggctctgcctggctgtcaccgcagtgctcgga
ggaactattctttggagactcaataagagccaagggcaggtgggaaaaaaggtggtctgc
ctggcaggcctctggggaggggcgtgcctgctcagcctatccctctcctggggcttgctc
ctcttctccttttcatgcttcatcatgtatacttacttttctggccaagagtttttacct
gtggatcaaaaggcgatactgatcacaggtagcgattctggatttggccatgctttgtcc
aagtatctggataagctgggcttcacagtatttgctggggttctgaatgaagaaggacca
ggagcagaggaattacgaagaacttgctccacgcgcctctctgtgctccagctggacata
accaaaccgcagcagataaaagatgctcacagcaaagtcatggaaaaagtgcagaacaga
ggactgtgggctgtggtcaacaatgccgggatatttagctatccagttgatggagagctc
actcccatgactgagtacaagcgatgcatggctgtgaacttcttcgggactgtggaagtc
acaaaggcatttttgcctcttcttaggaaatccaaggggaggctggtgaacatcagtagc
ctggcaggagcgatcccaatggagaggctggcagcctatagctcatctaaggcggctctg
accatgttttcagcagtcttgagacaagagctatccaactggggagttaaagtctctgtt
atccagcctggaggcttccaaacgaatatcgcaggcacgagtgacatgtgggacaagctg
gagaagagcatcctggaccacctccccactgacgtgcaagaggactatggccaggactac
atccataggcaacgcaattatttaagattgatcaacaacttctctgatccgaacatctcc
cctgtactcctggacatccatcatgccatctctgctaagagcccctgtgcattttatgca
ccagggaaaatgacttatccatggatctattttgtttcctttagccctactggcatattt
gattattttgccaaaaaaaatcatggccatggaaggatcatgcccagagctttaagcaag
cctaatgggaagaatgaggccatatag
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