Vulpes vulpes (red fox): 112909277
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Entry
112909277 CDS
T05911
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
vvp
Vulpes vulpes (red fox)
Pathway
vvp00230
Purine metabolism
vvp00670
One carbon pool by folate
vvp01100
Metabolic pathways
vvp01523
Antifolate resistance
Module
vvp_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
vvp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
112909277 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
112909277 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
112909277 (GART)
Enzymes [BR:
vvp01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
112909277 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
112909277 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
112909277 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
CPSase_L_D2
Dala_Dala_lig_C
ATP-grasp_3
ATP-grasp_4
RimK
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-GeneID:
112909277
NCBI-ProteinID:
XP_025840948
UniProt:
A0A3Q7R614
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAARVLVIGSGGREHTLAWKLAQSNHVKHVLVAPGNAGTACLEKISNTAISISDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIAGNLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TARWKAFTKPEEACSFIMSADFPALVVKASGLAAGKGVIVAKSTEEACKAVQEIMQDKAF
GAAGETIVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDHGPNTGGMGAYCPAP
QVSKDLFLKIKNTILQRTVDGMQQEGMPYTGVLYAGIMLTKEGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPVWLDNRAAITVVMASKGYPGDYTKGVEITGFPEA
HALGLEVFHAGTALKDGKVVTNGGRVLTVTAIQENLLLALEEAKKGLSAIKFEGAFYRKD
IGYRAIAFFQQPRGLTYKESGVDIAAGNMLVQKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFRDPLLACGTDGVGTKLKIAQQCDKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLDTTEAVVTGIARACRKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDVVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKFGVDLDAQSWRVPRIFSWLQQEG
HLSEEEMARTFNCGVGAALVVSKDLTEQILKDIKQHKEEAWVIGKVVACPEGSPRVKVRH
LIETMQINGSVLENGTLKNHFSVQPKKARVAVLISGTGSNLQALIDSTREPSSCAHIVVV
ISNKAAVAGLDKAERAGIPTRVINHKLYKSRVEFDTAIDQVLEEYSTDIVCLAGFMRILS
GPFVRKWDGKMLNIHPSLLPSFKGSNAHEQALEAGVTVTGCTVHFVAEDVDAGQIILQES
VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGAIRLGENGKIRWVTED
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtaatcggcagtggaggaagggagcataccctggcctggaaa
cttgcacagtctaaccatgtcaaacatgtgttggttgccccaggaaatgcaggcactgcc
tgcttggaaaagatttcaaataccgccatctccatcagtgaccacactgcccttgctcaa
ttctgcaaagatgagaaaattgaattcgtggttgttggaccagaggcacctctggctgct
ggaatcgctgggaacctgacatctgcaggagtgcgatgctttggtcccactgcagaagca
gctcaattagagtctagcaagagatttgccaaagagtttatggaccgacatggaatccca
actgcacggtggaaagctttcaccaaacctgaagaggcctgcagctttataatgagtgca
gacttccctgctttggttgtaaaggccagtggtcttgcagctggaaaaggggtgattgtt
gccaagagcacagaagaggcctgcaaggctgtacaggagattatgcaggataaagctttt
ggagcagctggagaaacaattgtcatcgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgcttcactgatggaaggactgtggcccccatgcccccagcacaagaccataagcga
ttgctggaaggagatcatggccccaacacagggggaatgggcgcctattgtccagcacct
caggtttctaaggatttgttcctgaaaataaaaaacaccattcttcagagaacagtggat
ggcatgcagcaggagggcatgccatacacaggtgttctctacgctggtataatgctgacc
aaggagggcccaaaagttctggagtttaattgccgttttggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgatctttatgaagtgattcagtctaccttggatggcctg
ctctgcacatctctgcctgtttggcttgataaccgtgctgccataactgtggtaatggca
agtaaaggctatccaggagattacaccaagggtgtggagataacagggtttcctgaggct
cacgctttaggactggaggtgttccatgcaggcactgccctgaaagatggcaaagtggtg
actaacgggggtagagtccttacggtaacagcaatccaggaaaatctcctcttggccctt
gaagaagcaaagaaaggactatctgctataaaatttgagggagccttttacaggaaggac
attggctatcgtgccatagccttcttccagcagcccaggggcctgacttacaaggaatct
ggggtagacattgcagctggaaatatgctggtccaaaaaattaaacctttagcaaaagct
acttccagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcagagatcctcttctggcatgtggaacagatggtgttggaactaaactg
aagattgcccagcagtgtgataaacatgatactattggtcaagatttggttgcaatgtgt
gtcaatgacattctagcccaaggggctgagccccttttcttcctcgattacttttcctgt
ggaaaacttgacctcgatacaactgaagcagttgtcactggaattgccagagcttgcaga
aaagctggatgtgctctccttggaggtgaaactgcagaaatgcctgacatgtatcctccg
ggagaatatgacctagctggttttgccgttggtgccatggagcgggatcagaaacttcct
cacctggaaagaatcactgaaggggatgttgttattggaatagcttcgtctggtcttcac
agcaatggatttagccttgtcaggaaaattgtagcaaaatcttccctccagtactcgtct
ccagcacccgatggctgtggtgaccagaccttaggggacttacttctaactccaacccga
atctacagccattcgctgttacctgtcctacgttcaggacatgtgaaggcctttgcccat
attactggtggaggattgctagaaaacatccccagagtccttcctcagaaatttggggtg
gatttagatgcccaaagctggagggtccccaggatcttttcatggctacagcaggaagga
cacctctctgaagaagagatggcgagaacatttaactgtggagttggggctgccctcgtg
gtatcaaaggatctgacggagcagattctgaaggatattaagcagcacaaggaagaagcc
tgggtgattggcaaagtggtggcatgtcctgaaggttctcctcgtgtgaaagtcaggcat
ctgatagaaactatgcaaataaatgggtcagtattagagaatggcaccctgaaaaatcat
ttctctgttcaaccaaaaaaggcaagagtggctgtcttaatatctggaacaggatcaaac
ctgcaagctcttatagacagtactagggagcccagtagctgtgcacacattgttgttgtt
atctccaacaaagctgcagtggctggtttagataaagcggaaagagctggaattcccacc
agagtaatcaaccataaattatataaaagtcgtgtagaatttgacactgccattgaccaa
gtccttgaagagtattccacagacatagtctgtcttgcaggattcatgagaattttatct
ggcccctttgtcagaaaatgggatgggaagatgctcaacatccacccctccttgctccct
tcttttaagggttcaaatgcccatgagcaagccctggaagctggggtcacagtcactggg
tgtactgtgcactttgtagctgaagatgtagatgctggacaaattattttacaagaatct
gttccagtgaagagaggtgacactgttgcaactctgtcggaaagagtgaaattagcagag
cataaaatatttcccgcagccctccagctggtagccagtggagctataaggcttggagaa
aatggcaagatccgttgggtcacagaggattga
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