Xenopus laevis (African clawed frog): 100113430
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Entry
100113430 CDS
T01010
Symbol
map3k12.S, dlk, map3k12, map3k12-a, map3k12-b, map3k12a, mekk12, muk, zpk, zpkp1
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 12 S homeolog
KO
K04423
mitogen-activated protein kinase kinase kinase 12 [EC:
2.7.11.25
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla04010
MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100113430 (map3k12.S)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
xla01001
]
100113430 (map3k12.S)
Enzymes [BR:
xla01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
100113430 (map3k12.S)
Protein kinases [BR:
xla01001
]
Serine/threonine kinases: TKL group
MLK family
100113430 (map3k12.S)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Pkinase_fungal
ABC1
Motif
Other DBs
NCBI-GeneID:
100113430
NCBI-ProteinID:
NP_001094411
Xenbase:
XB-GENE-1020622
UniProt:
A7J1T1
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Position
2S:138418318..138474815
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AA seq
807 aa
AA seq
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MACLHETRTPSPSFASLLSDGPIRRLDIDTPPGCTPEQELTPTQCVLRGMVRSEGGSPHS
EDCTTPLTHSEPQDPQKAEDRGGGGAEDCPLEDRPCRALGEGRMQCQAGVGFLGGLFGCL
RPVWAMIGKTYSTEHKQGEDPWEIPFEEIQDLQWVGSGAQGAVFLGKFHGEEVAVKKVRD
IKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCARGQLYEVLRAGRKITPSLLVDW
SMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDLVKISDFGTSKELSDKSTKMSFAGTVAW
MAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLNLPVPSSCP
DGFKLLLRQCWESKPRNRPSFRQILLHLDIASADILSTPQETYFKSQVEWRDEVRLYFEK
IKSEGTCLQRLEEELITRRREELRHALDIREHYERKLQRANTLYVELNSLMLQLELKEKE
LLRREQVMEKKYPAILRQPRPSSTVEKLIKKRNVPQKLSPHGKRPDILKSEVLLPKVDSV
LSPSTPTGCQKLPPSPGRGRRGKPRYRKAKDMVNLRAAVTPETTPQSQPPARDPHPLSSS
SPDLLSTPLEAEARRGSQSAECSPVRSLPGPPSPDSPSGRAAGSRAARGGQHLTPSARLY
RAAVTRSQKRGLSSEEEEGEVDSELEMERRQRWPTGMSQNQSPSSENLSDGEEGNTTDPS
HSVTPDVLSTNTDERPDERSEDLVSQSSEPPLDLLTQSDGLSEKEAVIQKVKTQLSNEQT
AGENVVLYDDSDCDSVELDHSLSATTS
NT seq
2424 nt
NT seq
+upstream
nt +downstream
nt
atggcttgtctacatgaaacacgcactccctcgccttcctttgccagtttgctatcagat
ggaccaattcgccggctggatatcgacactcctcctggctgtacccctgagcaagaactg
acacccacacaatgtgtcctccgtggtatggtgcgatctgaggggggctctcctcacagt
gaagactgtacaacccccctcactcacagtgagcctcaggacccacaaaaggctgaagac
aggggtggagggggtgcagaagattgtcctttagaagacagaccatgtcgggcattggga
gaaggccgtatgcagtgtcaagcaggggttggctttctcggagggctttttggatgtctg
agacctgtctgggcaatgattgggaaaacttattcaacagaacacaagcagggagaagac
ccatgggagattccatttgaagaaatccaggacctgcagtgggtgggcagtggagcccaa
ggagctgtcttccttgggaaattccatggtgaagaagtggctgtaaagaaagtgcgagat
attaaagaaacagacatcaaacacctccgaaagctaaagcatcctaatatcatcaccttc
aaaggggtgtgcacacaagctccttgttactgcatcttaatggaattttgtgctcggggg
caactgtatgaagtcttgcgtgctgggagaaaaataaccccctccttattagtagactgg
tccatgggaattgctggtggaatgaactacttacatctccataaaataatccaccgtgac
ctcaaatcacctaacatgctcatcacctatgatgacttggtcaaaatttctgactttggt
acctccaaagagttgagtgataagagcaccaagatgtcctttgcgggtacagttgcttgg
atggcaccagaagtgatacgcaatgagcctgtttctgagaaggtggatatttggtccttt
ggggtggttctttgggagctgttgactggagagatcccttataaggatgtggattcctct
gccataatttggggggtgggcagcaatagcctgaacctccctgtgccatctagttgtcca
gatggattcaaactgctgctaaggcaatgctgggagagcaagccaagaaatcgcccctcg
tttcgtcaaatcctgctgcacttagatattgcttctgccgatatcctgtccacccctcag
gagacctacttcaaatcccaggtggaatggcgagatgaggttcggttatattttgagaaa
atcaagtcagaaggaacgtgtctgcagcgtttggaagaggagctgataacacggcgccgg
gaggagttaaggcatgccctggatattcgagagcactatgagcgcaagttgcagagagca
aacactctgtacgtggagctgaactcactcatgctgcaactggagttgaaagagaaggag
ttgctcaggagagagcaagtcatggaaaagaaatatcctgcaatactgcgccagcctcga
ccctccagtacagtggaaaaacttatcaagaagaggaatgtacctcagaaattatcccca
catgggaaaaggccagacattttgaaatctgaagtcctgctgccaaaggtagactctgtc
ttgtcaccctctacccccactggttgccagaaacttcccccatccccaggaaggggtcgt
cggggaaaacctcggtaccgcaaagcaaaggacatggtcaacctaagagctgcagttacc
cctgagaccacccctcaaagtcaacctcctgctcgggaccctcatcctctgtcttcctca
agccctgacctgttatctacccctctggaggccgaagcccgtaggggaagtcagagtgca
gagtgttcccctgttcgttctttgcctggccctccaagccctgactccccctcaggtcgg
gcagcagggagcagagcagccagaggagggcagcacctcaccccatcagccaggctgtac
agagcagctgtcacaaggagtcagaaacgagggttgtcctccgaggaggaagagggggaa
gttgacagtgaattggagatggagagaagacagaggtggcccacagggatgtcccagaat
cagtcaccaagttcggagaatctgtcagatggggaggaagggaacacaactgacccctct
cacagtgtcacccctgatgtgttgagcactaacacagatgaacgtccggatgaacgatct
gaggatctggtgtcccaaagctctgaaccccctctggatcttctcacccagtctgatgga
ctctcagagaaggaggcggttatccagaaagtgaaaacccagctgagcaatgaacagact
gcaggagagaatgtcgtcctgtatgatgactctgactgtgacagcgttgaacttgaccat
tcgctctctgcaacgacctcatga
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