Homo sapiens (human): 815
Help
Entry
815 CDS
T01001
Symbol
CAMK2A, CAMKA, CaMKIINalpha, CaMKIIalpha, MRD53, MRT63
Name
(RefSeq) calcium/calmodulin dependent protein kinase II alpha
KO
K04515
calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:
2.7.11.17
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04012
ErbB signaling pathway
hsa04020
Calcium signaling pathway
hsa04024
cAMP signaling pathway
hsa04066
HIF-1 signaling pathway
hsa04114
Oocyte meiosis
hsa04148
Efferocytosis
hsa04217
Necroptosis
hsa04261
Adrenergic signaling in cardiomyocytes
hsa04310
Wnt signaling pathway
hsa04360
Axon guidance
hsa04713
Circadian entrainment
hsa04720
Long-term potentiation
hsa04722
Neurotrophin signaling pathway
hsa04725
Cholinergic synapse
hsa04728
Dopaminergic synapse
hsa04740
Olfactory transduction
hsa04750
Inflammatory mediator regulation of TRP channels
hsa04911
Insulin secretion
hsa04912
GnRH signaling pathway
hsa04916
Melanogenesis
hsa04921
Oxytocin signaling pathway
hsa04922
Glucagon signaling pathway
hsa04925
Aldosterone synthesis and secretion
hsa04934
Cushing syndrome
hsa04971
Gastric acid secretion
hsa05012
Parkinson disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05031
Amphetamine addiction
hsa05152
Tuberculosis
hsa05200
Pathways in cancer
hsa05205
Proteoglycans in cancer
hsa05214
Glioma
hsa05415
Diabetic cardiomyopathy
hsa05417
Lipid and atherosclerosis
Network
nt06220
Calcium signaling (cancer)
nt06273
Glioma
nt06316
Renin-angiotensin-aldosterone signaling
nt06528
Calcium signaling
nt06535
Efferocytosis
Element
N00026
EGF-EGFR-PLCG-CAMK signaling pathway
N00027
Amplified EGFR to PLCG-CAMK signaling pathway
N00028
PDGF-PDGFR-PLCG-CAMK signaling pathway
N00029
Amplified PDGFR to PLCG-CAMK signaling pathway
N00301
Angiotensin-aldosterone signaling pathway
N00302
Mutation-activated CACNA1D/H to angiotensin-aldosterone signaling pathway
N00303
Mutation-activated KCNJ5 to angiotensin-aldosterone signaling pathway
N00304
Mutation-inactivated ATP1A1 to angiotensin-aldosterone signaling pathway
N00305
Mutation-inactivated ATP2B3 to angiotensin-aldosterone signaling pathway
N01648
Ca2+/CAM-CAMK signaling pathway
N01775
Inactivation of CaMKII by inducing SERCA2
N01776
CaMK2-p38-MK2-ALOX5 pathway
Disease
H00768
Autosomal recessive intellectual developmental disorder
H00773
Autosomal dominant intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
815 (CAMK2A)
04310 Wnt signaling pathway
815 (CAMK2A)
04066 HIF-1 signaling pathway
815 (CAMK2A)
04020 Calcium signaling pathway
815 (CAMK2A)
04024 cAMP signaling pathway
815 (CAMK2A)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
815 (CAMK2A)
09143 Cell growth and death
04114 Oocyte meiosis
815 (CAMK2A)
04217 Necroptosis
815 (CAMK2A)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
815 (CAMK2A)
04922 Glucagon signaling pathway
815 (CAMK2A)
04912 GnRH signaling pathway
815 (CAMK2A)
04921 Oxytocin signaling pathway
815 (CAMK2A)
04916 Melanogenesis
815 (CAMK2A)
04925 Aldosterone synthesis and secretion
815 (CAMK2A)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
815 (CAMK2A)
09154 Digestive system
04971 Gastric acid secretion
815 (CAMK2A)
09156 Nervous system
04725 Cholinergic synapse
815 (CAMK2A)
04728 Dopaminergic synapse
815 (CAMK2A)
04720 Long-term potentiation
815 (CAMK2A)
04722 Neurotrophin signaling pathway
815 (CAMK2A)
09157 Sensory system
04740 Olfactory transduction
815 (CAMK2A)
04750 Inflammatory mediator regulation of TRP channels
815 (CAMK2A)
09158 Development and regeneration
04360 Axon guidance
815 (CAMK2A)
09159 Environmental adaptation
04713 Circadian entrainment
815 (CAMK2A)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
815 (CAMK2A)
05205 Proteoglycans in cancer
815 (CAMK2A)
09162 Cancer: specific types
05214 Glioma
815 (CAMK2A)
09171 Infectious disease: bacterial
05152 Tuberculosis
815 (CAMK2A)
09164 Neurodegenerative disease
05012 Parkinson disease
815 (CAMK2A)
05022 Pathways of neurodegeneration - multiple diseases
815 (CAMK2A)
09165 Substance dependence
05031 Amphetamine addiction
815 (CAMK2A)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
815 (CAMK2A)
05415 Diabetic cardiomyopathy
815 (CAMK2A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
815 (CAMK2A)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
815 (CAMK2A)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.17 Ca2+/calmodulin-dependent protein kinase
815 (CAMK2A)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: CAMK group
CAMK2 family
815 (CAMK2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
CaMKII_AD
PK_Tyr_Ser-Thr
DUF4440
SnoaL_3
SnoaL_2
APH
Kdo
SnoaL_4
Motif
Other DBs
NCBI-GeneID:
815
NCBI-ProteinID:
NP_741960
OMIM:
114078
HGNC:
1460
Ensembl:
ENSG00000070808
UniProt:
Q9UQM7
Q7LDD5
A8K161
Q8IWE0
Structure
PDB
LinkDB
All DBs
Position
5:complement(150219491..150290130)
Genome browser
AA seq
478 aa
AA seq
DB search
MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE
ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL
EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL
SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV
TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK
GAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEA
ISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIH
LMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH
NT seq
1437 nt
NT seq
+upstream
nt +downstream
nt
atggccaccatcacctgcacccgcttcacggaagagtaccagctcttcgaggaattgggc
aagggagccttctcggtggtgcgaaggtgtgtgaaggtgctggctggccaggagtatgct
gccaagatcatcaacacaaagaagctgtcagccagagaccatcagaagctggagcgtgaa
gcccgcatctgccgcctgctgaagcaccccaacatcgtccgactacatgacagcatctca
gaggagggacaccactacctgatcttcgacctggtcactggtggggaactgtttgaagat
atcgtggcccgggagtattacagtgaggcggatgccagtcactgtatccagcagatcctg
gaggctgtgctgcactgccaccagatgggggtggtgcaccgggacctgaagcctgagaat
ctgttgctggcctccaagctcaagggtgccgcagtgaagctggcagactttggcctggcc
atagaggtggagggggagcagcaggcatggtttgggtttgcagggactcctggatatctc
tccccagaagtgctgcggaaggacccgtacgggaagcctgtggacctgtgggcttgtggg
gtcatcctgtacatcctgctggttgggtaccccccgttctgggatgaggaccagcaccgc
ctgtaccagcagatcaaagccggcgcctatgatttcccatcgccggaatgggacactgtc
accccggaagccaaggatctgatcaataagatgctgaccattaacccatccaaacgcatc
acagctgccgaagcccttaagcacccctggatctcgcaccgctccaccgtggcatcctgc
atgcacagacaggagaccgtggactgcctgaagaagttcaatgccaggaggaaactgaag
ggagccattctcaccacgatgctggccaccaggaacttctccggagggaagagtggggga
aacaagaagagcgatggtgtgaaggaatcctcagagagcaccaacaccaccatcgaggat
gaagacaccaaagtgcggaaacaggaaattataaaagtgacagagcagctgattgaagcc
ataagcaatggagattttgagtcctacacgaagatgtgcgaccctggcatgacagccttc
gaacctgaggccctggggaacctggttgagggcctggacttccatcgattctattttgaa
aacctgtggtcccggaacagcaagcccgtgcacaccaccatcctgaatccccacatccac
ctgatgggcgacgagtcagcctgcatcgcctacatccgcatcacgcagtacctggacgct
ggcggcatcccacgcaccgcccagtcggaggagacccgtgtctggcaccgccgggatggc
aaatggcagatcgtccacttccacagatctggggcgccctccgtcctgccccactga
Homo sapiens (human): 816
Help
Entry
816 CDS
T01001
Symbol
CAMK2B, CAM2, CAMK2, CAMKB, CaMKIIbeta, MRD54
Name
(RefSeq) calcium/calmodulin dependent protein kinase II beta
KO
K04515
calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:
2.7.11.17
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04012
ErbB signaling pathway
hsa04020
Calcium signaling pathway
hsa04024
cAMP signaling pathway
hsa04066
HIF-1 signaling pathway
hsa04114
Oocyte meiosis
hsa04148
Efferocytosis
hsa04217
Necroptosis
hsa04261
Adrenergic signaling in cardiomyocytes
hsa04310
Wnt signaling pathway
hsa04360
Axon guidance
hsa04713
Circadian entrainment
hsa04720
Long-term potentiation
hsa04722
Neurotrophin signaling pathway
hsa04725
Cholinergic synapse
hsa04728
Dopaminergic synapse
hsa04740
Olfactory transduction
hsa04750
Inflammatory mediator regulation of TRP channels
hsa04911
Insulin secretion
hsa04912
GnRH signaling pathway
hsa04916
Melanogenesis
hsa04921
Oxytocin signaling pathway
hsa04922
Glucagon signaling pathway
hsa04925
Aldosterone synthesis and secretion
hsa04934
Cushing syndrome
hsa04971
Gastric acid secretion
hsa05012
Parkinson disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05031
Amphetamine addiction
hsa05152
Tuberculosis
hsa05200
Pathways in cancer
hsa05205
Proteoglycans in cancer
hsa05214
Glioma
hsa05415
Diabetic cardiomyopathy
hsa05417
Lipid and atherosclerosis
Network
nt06220
Calcium signaling (cancer)
nt06273
Glioma
nt06316
Renin-angiotensin-aldosterone signaling
nt06528
Calcium signaling
nt06535
Efferocytosis
Element
N00026
EGF-EGFR-PLCG-CAMK signaling pathway
N00027
Amplified EGFR to PLCG-CAMK signaling pathway
N00028
PDGF-PDGFR-PLCG-CAMK signaling pathway
N00029
Amplified PDGFR to PLCG-CAMK signaling pathway
N00301
Angiotensin-aldosterone signaling pathway
N00302
Mutation-activated CACNA1D/H to angiotensin-aldosterone signaling pathway
N00303
Mutation-activated KCNJ5 to angiotensin-aldosterone signaling pathway
N00304
Mutation-inactivated ATP1A1 to angiotensin-aldosterone signaling pathway
N00305
Mutation-inactivated ATP2B3 to angiotensin-aldosterone signaling pathway
N01648
Ca2+/CAM-CAMK signaling pathway
N01775
Inactivation of CaMKII by inducing SERCA2
N01776
CaMK2-p38-MK2-ALOX5 pathway
Disease
H00773
Autosomal dominant intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
816 (CAMK2B)
04310 Wnt signaling pathway
816 (CAMK2B)
04066 HIF-1 signaling pathway
816 (CAMK2B)
04020 Calcium signaling pathway
816 (CAMK2B)
04024 cAMP signaling pathway
816 (CAMK2B)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
816 (CAMK2B)
09143 Cell growth and death
04114 Oocyte meiosis
816 (CAMK2B)
04217 Necroptosis
816 (CAMK2B)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
816 (CAMK2B)
04922 Glucagon signaling pathway
816 (CAMK2B)
04912 GnRH signaling pathway
816 (CAMK2B)
04921 Oxytocin signaling pathway
816 (CAMK2B)
04916 Melanogenesis
816 (CAMK2B)
04925 Aldosterone synthesis and secretion
816 (CAMK2B)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
816 (CAMK2B)
09154 Digestive system
04971 Gastric acid secretion
816 (CAMK2B)
09156 Nervous system
04725 Cholinergic synapse
816 (CAMK2B)
04728 Dopaminergic synapse
816 (CAMK2B)
04720 Long-term potentiation
816 (CAMK2B)
04722 Neurotrophin signaling pathway
816 (CAMK2B)
09157 Sensory system
04740 Olfactory transduction
816 (CAMK2B)
04750 Inflammatory mediator regulation of TRP channels
816 (CAMK2B)
09158 Development and regeneration
04360 Axon guidance
816 (CAMK2B)
09159 Environmental adaptation
04713 Circadian entrainment
816 (CAMK2B)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
816 (CAMK2B)
05205 Proteoglycans in cancer
816 (CAMK2B)
09162 Cancer: specific types
05214 Glioma
816 (CAMK2B)
09171 Infectious disease: bacterial
05152 Tuberculosis
816 (CAMK2B)
09164 Neurodegenerative disease
05012 Parkinson disease
816 (CAMK2B)
05022 Pathways of neurodegeneration - multiple diseases
816 (CAMK2B)
09165 Substance dependence
05031 Amphetamine addiction
816 (CAMK2B)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
816 (CAMK2B)
05415 Diabetic cardiomyopathy
816 (CAMK2B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
816 (CAMK2B)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
816 (CAMK2B)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.17 Ca2+/calmodulin-dependent protein kinase
816 (CAMK2B)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: CAMK group
CAMK2 family
816 (CAMK2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
CaMKII_AD
PK_Tyr_Ser-Thr
DUF4440
SnoaL_3
SnoaL_2
APH
Pkinase_fungal
Kdo
SnoaL_4
Motif
Other DBs
NCBI-GeneID:
816
NCBI-ProteinID:
NP_001211
OMIM:
607707
HGNC:
1461
Ensembl:
ENSG00000058404
UniProt:
Q13554
A4D2J9
Structure
PDB
LinkDB
All DBs
Position
7:complement(44217154..44326013)
Genome browser
AA seq
666 aa
AA seq
DB search
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK
NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKAPRVPDILSSVR
RGSGAPEAEGPLPCPSPAPFSPLPAPSPRISDILNSVRRGSGTPEAEGPLSAGPPPCLSP
ALLGPLSSPSPRISDILNSVRRGSGTPEAEGPSPVGPPPCPSPTIPGPLPTPSRKQEIIK
TTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHT
TILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGA
PVAPLQ
NT seq
2001 nt
NT seq
+upstream
nt +downstream
nt
atggccaccacggtgacctgcacccgcttcaccgacgagtaccagctctacgaggatatt
ggcaagggggctttctctgtggtccgacgctgtgtcaagctctgcaccggccatgagtat
gcagccaagatcatcaacaccaagaagctgtcagccagagatcaccagaagctggagaga
gaggctcggatctgccgccttctgaagcattccaacatcgtgcgtctccacgacagcatc
tccgaggagggcttccactacctggtcttcgatctggtcactggtggggagctctttgaa
gacattgtggcgagagagtactacagcgaggctgatgccagtcactgtatccagcagatc
ctggaggccgttctccattgtcaccaaatgggggtcgtccacagagacctcaagccggag
aacctgcttctggccagcaagtgcaaaggggctgcagtgaagctggcagacttcggccta
gctatcgaggtgcagggggaccagcaggcatggtttggtttcgctggcacaccaggctac
ctgtcccctgaggtccttcgcaaagaggcgtatggcaagcctgtggacatctgggcatgt
ggggtgatcctgtacatcctgctcgtgggctacccacccttctgggacgaggaccagcac
aagctgtaccagcagatcaaggctggtgcctatgacttcccgtcccctgagtgggacacc
gtcactcctgaagccaaaaacctcatcaaccagatgctgaccatcaaccctgccaagcgc
atcacagcccatgaggccctgaagcacccgtgggtctgccaacgctccacggtagcatcc
atgatgcacagacaggagactgtggagtgtctgaaaaagttcaatgccaggagaaagctc
aagggagccatcctcaccaccatgctggccacacggaatttctcagtgggcagacagacc
accgctccggccacaatgtccaccgcggcctccggcaccaccatggggctggtggaacaa
gccaagagtttactcaacaagaaagcagatggagtcaagccccagacgaatagcaccaaa
aacagtgcagccgccaccagccccaaagggacgcttcctcctgccgccctggagcctcaa
accaccgtcatccataacccagtggacgggattaaggagtcttctgacagtgccaatacc
accatagaggatgaagacgctaaagcccccagggtccccgacatcctgagctcagtgagg
aggggctcgggagccccagaagccgaggggcccctgccctgcccatctccggctcccttt
agccccctgccagccccatcccccaggatctctgacatcctgaactctgtgagaaggggt
tcaggaaccccagaagccgagggccccctctcagcggggcccccgccctgcctgtctccg
gctctcctaggccccctgtcctccccgtcccccaggatctctgacatcctgaactctgtg
aggaggggctcagggaccccagaagccgagggcccctcgccagtggggcccccgccctgc
ccatctccgactatccctggccccctgcccaccccatcccggaagcaggagatcattaag
accacggagcagctcatcgaggccgtcaacaacggtgactttgaggcctacgcgaaaatc
tgtgacccagggctgacctcgtttgagcctgaagcactgggcaacctggttgaagggatg
gacttccacagattctacttcgagaacctgctggccaagaacagcaagccgatccacacg
accatcctgaacccacacgtgcacgtcattggagaggatgccgcctgcatcgcttacatc
cggctcacgcagtacattgacgggcagggccggccccgcaccagccagtctgaggagacc
cgcgtgtggcaccgccgcgacggcaagtggcagaacgtgcacttccactgctcgggcgcg
cctgtggccccgctgcagtga
Homo sapiens (human): 817
Help
Entry
817 CDS
T01001
Symbol
CAMK2D, CAMKD
Name
(RefSeq) calcium/calmodulin dependent protein kinase II delta
KO
K04515
calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:
2.7.11.17
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04012
ErbB signaling pathway
hsa04020
Calcium signaling pathway
hsa04024
cAMP signaling pathway
hsa04066
HIF-1 signaling pathway
hsa04114
Oocyte meiosis
hsa04148
Efferocytosis
hsa04217
Necroptosis
hsa04261
Adrenergic signaling in cardiomyocytes
hsa04310
Wnt signaling pathway
hsa04360
Axon guidance
hsa04713
Circadian entrainment
hsa04720
Long-term potentiation
hsa04722
Neurotrophin signaling pathway
hsa04725
Cholinergic synapse
hsa04728
Dopaminergic synapse
hsa04740
Olfactory transduction
hsa04750
Inflammatory mediator regulation of TRP channels
hsa04911
Insulin secretion
hsa04912
GnRH signaling pathway
hsa04916
Melanogenesis
hsa04921
Oxytocin signaling pathway
hsa04922
Glucagon signaling pathway
hsa04925
Aldosterone synthesis and secretion
hsa04934
Cushing syndrome
hsa04971
Gastric acid secretion
hsa05012
Parkinson disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05031
Amphetamine addiction
hsa05152
Tuberculosis
hsa05200
Pathways in cancer
hsa05205
Proteoglycans in cancer
hsa05214
Glioma
hsa05415
Diabetic cardiomyopathy
hsa05417
Lipid and atherosclerosis
Network
nt06220
Calcium signaling (cancer)
nt06273
Glioma
nt06316
Renin-angiotensin-aldosterone signaling
nt06528
Calcium signaling
nt06535
Efferocytosis
Element
N00026
EGF-EGFR-PLCG-CAMK signaling pathway
N00027
Amplified EGFR to PLCG-CAMK signaling pathway
N00028
PDGF-PDGFR-PLCG-CAMK signaling pathway
N00029
Amplified PDGFR to PLCG-CAMK signaling pathway
N00301
Angiotensin-aldosterone signaling pathway
N00302
Mutation-activated CACNA1D/H to angiotensin-aldosterone signaling pathway
N00303
Mutation-activated KCNJ5 to angiotensin-aldosterone signaling pathway
N00304
Mutation-inactivated ATP1A1 to angiotensin-aldosterone signaling pathway
N00305
Mutation-inactivated ATP2B3 to angiotensin-aldosterone signaling pathway
N01648
Ca2+/CAM-CAMK signaling pathway
N01775
Inactivation of CaMKII by inducing SERCA2
N01776
CaMK2-p38-MK2-ALOX5 pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
817 (CAMK2D)
04310 Wnt signaling pathway
817 (CAMK2D)
04066 HIF-1 signaling pathway
817 (CAMK2D)
04020 Calcium signaling pathway
817 (CAMK2D)
04024 cAMP signaling pathway
817 (CAMK2D)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
817 (CAMK2D)
09143 Cell growth and death
04114 Oocyte meiosis
817 (CAMK2D)
04217 Necroptosis
817 (CAMK2D)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
817 (CAMK2D)
04922 Glucagon signaling pathway
817 (CAMK2D)
04912 GnRH signaling pathway
817 (CAMK2D)
04921 Oxytocin signaling pathway
817 (CAMK2D)
04916 Melanogenesis
817 (CAMK2D)
04925 Aldosterone synthesis and secretion
817 (CAMK2D)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
817 (CAMK2D)
09154 Digestive system
04971 Gastric acid secretion
817 (CAMK2D)
09156 Nervous system
04725 Cholinergic synapse
817 (CAMK2D)
04728 Dopaminergic synapse
817 (CAMK2D)
04720 Long-term potentiation
817 (CAMK2D)
04722 Neurotrophin signaling pathway
817 (CAMK2D)
09157 Sensory system
04740 Olfactory transduction
817 (CAMK2D)
04750 Inflammatory mediator regulation of TRP channels
817 (CAMK2D)
09158 Development and regeneration
04360 Axon guidance
817 (CAMK2D)
09159 Environmental adaptation
04713 Circadian entrainment
817 (CAMK2D)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
817 (CAMK2D)
05205 Proteoglycans in cancer
817 (CAMK2D)
09162 Cancer: specific types
05214 Glioma
817 (CAMK2D)
09171 Infectious disease: bacterial
05152 Tuberculosis
817 (CAMK2D)
09164 Neurodegenerative disease
05012 Parkinson disease
817 (CAMK2D)
05022 Pathways of neurodegeneration - multiple diseases
817 (CAMK2D)
09165 Substance dependence
05031 Amphetamine addiction
817 (CAMK2D)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
817 (CAMK2D)
05415 Diabetic cardiomyopathy
817 (CAMK2D)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
817 (CAMK2D)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
817 (CAMK2D)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.17 Ca2+/calmodulin-dependent protein kinase
817 (CAMK2D)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: CAMK group
CAMK2 family
817 (CAMK2D)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
CaMKII_AD
PK_Tyr_Ser-Thr
DUF4440
SnoaL_3
SnoaL_2
Pkinase_fungal
Kdo
SnoaL_4
Motif
Other DBs
NCBI-GeneID:
817
NCBI-ProteinID:
NP_001212
OMIM:
607708
HGNC:
1462
Ensembl:
ENSG00000145349
UniProt:
Q13557
Structure
PDB
LinkDB
All DBs
Position
4:complement(113451032..113761738)
Genome browser
AA seq
499 aa
AA seq
DB search
MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT
VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL
KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA
INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH
LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIKPP
CIPNGKENFSGGTSLWQNI
NT seq
1500 nt
NT seq
+upstream
nt +downstream
nt
atggcttcgaccacaacctgcaccaggttcacggacgagtatcagcttttcgaggagctt
ggaaagggggcattctcagtggtgagaagatgtatgaaaattcctactggacaagaatat
gctgccaaaattatcaacaccaaaaagctttctgctagggatcatcagaaactagaaaga
gaagctagaatctgccgtcttttgaagcaccctaatattgtgcgacttcatgatagcata
tcagaagagggctttcactacttggtgtttgatttagttactggaggtgaactgtttgaa
gacatagtggcaagagaatactacagtgaagctgatgccagtcattgtatacagcagatt
ctagaaagtgttaatcattgtcacctaaatggcatagttcacagggacctgaagcctgag
aatttgcttttagctagcaaatccaagggagcagctgtgaaattggcagactttggctta
gccatagaagttcaaggggaccagcaggcgtggtttggttttgctggcacacctggatat
ctttctccagaagttttacgtaaagatccttatggaaagccagtggatatgtgggcatgt
ggtgtcattctctatattctacttgtggggtatccacccttctgggatgaagaccaacac
agactctatcagcagatcaaggctggagcttatgattttccatcaccagaatgggacacg
gtgactcctgaagccaaagacctcatcaataaaatgcttactatcaaccctgccaaacgc
atcacagcctcagaggcactgaagcacccatggatctgtcaacgttctactgttgcttcc
atgatgcacagacaggagactgtagactgcttgaagaaatttaatgctagaagaaaacta
aagggtgccatcttgacaactatgctggctacaaggaatttctcagcagccaagagtttg
ttgaagaaaccagatggagtaaaggagtcaactgagagttcaaatacaacaattgaggat
gaagatgtgaaagcacgaaagcaagagattatcaaagtcactgaacaactgatcgaagct
atcaacaatggggactttgaagcctacacaaaaatctgtgacccaggccttactgctttt
gaacctgaagctttgggtaatttagtggaagggatggattttcaccgattctactttgaa
aatgctttgtccaaaagcaataaaccaatccacactattattctaaaccctcatgtacat
ctggtaggggatgatgccgcctgcatagcatatattaggctcacacagtacatggatggc
agtggaatgccaaagacaatgcagtcagaagagactcgtgtgtggcaccgccgggatgga
aagtggcagaatgttcattttcatcgctcggggtcaccaacagtacccatcaagccaccc
tgtattccaaatgggaaagaaaacttctcaggaggcacctctttgtggcaaaacatctaa
Homo sapiens (human): 818
Help
Entry
818 CDS
T01001
Symbol
CAMK2G, CAMK, CAMK-II, CAMKG, MRD59
Name
(RefSeq) calcium/calmodulin dependent protein kinase II gamma
KO
K04515
calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:
2.7.11.17
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04012
ErbB signaling pathway
hsa04020
Calcium signaling pathway
hsa04024
cAMP signaling pathway
hsa04066
HIF-1 signaling pathway
hsa04114
Oocyte meiosis
hsa04148
Efferocytosis
hsa04217
Necroptosis
hsa04261
Adrenergic signaling in cardiomyocytes
hsa04310
Wnt signaling pathway
hsa04360
Axon guidance
hsa04713
Circadian entrainment
hsa04720
Long-term potentiation
hsa04722
Neurotrophin signaling pathway
hsa04725
Cholinergic synapse
hsa04728
Dopaminergic synapse
hsa04740
Olfactory transduction
hsa04750
Inflammatory mediator regulation of TRP channels
hsa04911
Insulin secretion
hsa04912
GnRH signaling pathway
hsa04916
Melanogenesis
hsa04921
Oxytocin signaling pathway
hsa04922
Glucagon signaling pathway
hsa04925
Aldosterone synthesis and secretion
hsa04934
Cushing syndrome
hsa04971
Gastric acid secretion
hsa05012
Parkinson disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05031
Amphetamine addiction
hsa05152
Tuberculosis
hsa05200
Pathways in cancer
hsa05205
Proteoglycans in cancer
hsa05214
Glioma
hsa05415
Diabetic cardiomyopathy
hsa05417
Lipid and atherosclerosis
Network
nt06220
Calcium signaling (cancer)
nt06273
Glioma
nt06316
Renin-angiotensin-aldosterone signaling
nt06528
Calcium signaling
nt06535
Efferocytosis
Element
N00026
EGF-EGFR-PLCG-CAMK signaling pathway
N00027
Amplified EGFR to PLCG-CAMK signaling pathway
N00028
PDGF-PDGFR-PLCG-CAMK signaling pathway
N00029
Amplified PDGFR to PLCG-CAMK signaling pathway
N00301
Angiotensin-aldosterone signaling pathway
N00302
Mutation-activated CACNA1D/H to angiotensin-aldosterone signaling pathway
N00303
Mutation-activated KCNJ5 to angiotensin-aldosterone signaling pathway
N00304
Mutation-inactivated ATP1A1 to angiotensin-aldosterone signaling pathway
N00305
Mutation-inactivated ATP2B3 to angiotensin-aldosterone signaling pathway
N01648
Ca2+/CAM-CAMK signaling pathway
N01775
Inactivation of CaMKII by inducing SERCA2
N01776
CaMK2-p38-MK2-ALOX5 pathway
Disease
H00773
Autosomal dominant intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
818 (CAMK2G)
04310 Wnt signaling pathway
818 (CAMK2G)
04066 HIF-1 signaling pathway
818 (CAMK2G)
04020 Calcium signaling pathway
818 (CAMK2G)
04024 cAMP signaling pathway
818 (CAMK2G)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
818 (CAMK2G)
09143 Cell growth and death
04114 Oocyte meiosis
818 (CAMK2G)
04217 Necroptosis
818 (CAMK2G)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
818 (CAMK2G)
04922 Glucagon signaling pathway
818 (CAMK2G)
04912 GnRH signaling pathway
818 (CAMK2G)
04921 Oxytocin signaling pathway
818 (CAMK2G)
04916 Melanogenesis
818 (CAMK2G)
04925 Aldosterone synthesis and secretion
818 (CAMK2G)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
818 (CAMK2G)
09154 Digestive system
04971 Gastric acid secretion
818 (CAMK2G)
09156 Nervous system
04725 Cholinergic synapse
818 (CAMK2G)
04728 Dopaminergic synapse
818 (CAMK2G)
04720 Long-term potentiation
818 (CAMK2G)
04722 Neurotrophin signaling pathway
818 (CAMK2G)
09157 Sensory system
04740 Olfactory transduction
818 (CAMK2G)
04750 Inflammatory mediator regulation of TRP channels
818 (CAMK2G)
09158 Development and regeneration
04360 Axon guidance
818 (CAMK2G)
09159 Environmental adaptation
04713 Circadian entrainment
818 (CAMK2G)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
818 (CAMK2G)
05205 Proteoglycans in cancer
818 (CAMK2G)
09162 Cancer: specific types
05214 Glioma
818 (CAMK2G)
09171 Infectious disease: bacterial
05152 Tuberculosis
818 (CAMK2G)
09164 Neurodegenerative disease
05012 Parkinson disease
818 (CAMK2G)
05022 Pathways of neurodegeneration - multiple diseases
818 (CAMK2G)
09165 Substance dependence
05031 Amphetamine addiction
818 (CAMK2G)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
818 (CAMK2G)
05415 Diabetic cardiomyopathy
818 (CAMK2G)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
818 (CAMK2G)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
818 (CAMK2G)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.17 Ca2+/calmodulin-dependent protein kinase
818 (CAMK2G)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: CAMK group
CAMK2 family
818 (CAMK2G)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
CaMKII_AD
PK_Tyr_Ser-Thr
DUF4440
SnoaL_3
SnoaL_2
Pkinase_fungal
Kdo
ABC1
SnoaL_4
Motif
Other DBs
NCBI-GeneID:
818
NCBI-ProteinID:
NP_001191421
OMIM:
602123
HGNC:
1463
Ensembl:
ENSG00000148660
UniProt:
Q13555
Structure
PDB
LinkDB
All DBs
Position
10:complement(73812501..73874555)
Genome browser
AA seq
539 aa
AA seq
DB search
MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI
LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY
LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL
KGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKPQSNNKNSL
VSPAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIE
AINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHV
HVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ
NT seq
1620 nt
NT seq
+upstream
nt +downstream
nt
atggccaccaccgccacctgcacccgtttcaccgacgactaccagctcttcgaggagctt
ggcaagggtgctttctctgtggtccgcaggtgtgtgaagaaaacctccacgcaggagtac
gcagcaaaaatcatcaataccaagaagttgtctgcccgggatcaccagaaactagaacgt
gaggctcggatatgtcgacttctgaaacatccaaacatcgtgcgcctccatgacagtatt
tctgaagaagggtttcactacctcgtgtttgaccttgttaccggcggggagctgtttgaa
gacattgtggccagagagtactacagtgaagcagatgccagccactgtatacatcagatt
ctggagagtgttaaccacatccaccagcatgacatcgtccacagggacctgaagcctgag
aacctgctgctggcgagtaaatgcaagggtgccgccgtcaagctggctgattttggccta
gccatcgaagtacagggagagcagcaggcttggtttggttttgctggcaccccaggttac
ttgtcccctgaggtcttgaggaaagatccctatggaaaacctgtggatatctgggcctgc
ggggtcatcctgtatatcctcctggtgggctatcctcccttctgggatgaggatcagcac
aagctgtatcagcagatcaaggctggagcctatgatttcccatcaccagaatgggacacg
gtaactcctgaagccaagaacttgatcaaccagatgctgaccataaacccagcaaagcgc
atcacggctgaccaggctctcaagcacccgtgggtctgtcaacgatccacggtggcatcc
atgatgcatcgtcaggagactgtggagtgtttgcgcaagttcaatgcccggagaaaactg
aagggtgccatcctcacgaccatgcttgtctccaggaacttctcagttggcaggcagagc
tccgcccccgcctcgcctgccgcgagcgccgccggcctggccgggcaagctgccaaaagc
ctattgaacaagaagtcggatggcggtgtcaagccacagagcaacaacaaaaacagtctc
gtaagcccagcccaagagcccgcgcccttgcagacggccatggagccacaaaccactgtg
gtacacaacgctacagatgggatcaagggctccacagagagctgcaacaccaccacagaa
gatgaggacctcaaagtgcgaaaacaggagatcattaagattacagaacagctgattgaa
gccatcaacaatggggactttgaggcctacacgaagatttgtgatccaggcctcacttcc
tttgagcctgaggcccttggtaacctcgtggaggggatggatttccataagttttacttt
gagaatctcctgtccaagaacagcaagcctatccataccaccatcctaaacccacacgtc
cacgtgattggggaggacgcagcgtgcatcgcctacatccgcctcacccagtacatcgac
gggcagggtcggcctcgcaccagccagtcagaagagacccgggtctggcaccgtcgggat
ggcaagtggctcaatgtccactatcactgctcaggggcccctgccgcaccgctgcagtga
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integrated database retrieval system
