KEGG   PATHWAY: ko00250
Entry
ko00250                     Pathway                                
Name
Alanine, aspartate and glutamate metabolism
Class
Metabolism; Amino acid metabolism
Pathway map
ko00250  Alanine, aspartate and glutamate metabolism
ko00250

Module
M00027  GABA (gamma-Aminobutyrate) shunt [PATH:ko00250]
M00740  Methylaspartate cycle [PATH:ko00250]
Other DBs
GO: 0006522 0006531 0006536
Orthology
K14454  aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
K14455  aspartate aminotransferase, mitochondrial [EC:2.6.1.1]
K00811  aspartate aminotransferase, chloroplastic [EC:2.6.1.1]
K00812  aspartate aminotransferase [EC:2.6.1.1]
K00813  aspartate aminotransferase [EC:2.6.1.1]
K11358  aspartate aminotransferase [EC:2.6.1.1]
K03334  L-amino-acid oxidase [EC:1.4.3.2]
K00278  L-aspartate oxidase [EC:1.4.3.16]
K01779  aspartate racemase [EC:5.1.1.13]
K00272  D-aspartate oxidase [EC:1.4.3.1]
K01424  L-asparaginase [EC:3.5.1.1]
K13051  L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
K05597  glutamin-(asparagin-)ase [EC:3.5.1.38]
K01914  aspartate--ammonia ligase [EC:6.3.1.1]
K01953  asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
K22457  asparagine---oxo-acid transaminase [EC:2.6.1.14]
K13566  omega-amidase [EC:3.5.1.3]
K09758  aspartate 4-decarboxylase [EC:4.1.1.12]
K00814  alanine transaminase [EC:2.6.1.2]
K14260  alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]
K00830  alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
K00827  alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase [EC:2.6.1.44 2.6.1.40]
K14272  glutamate--glyoxylate aminotransferase [EC:2.6.1.4 2.6.1.2 2.6.1.44]
K00259  alanine dehydrogenase [EC:1.4.1.1]
K19244  alanine dehydrogenase [EC:1.4.1.1]
K01744  aspartate ammonia-lyase [EC:4.3.1.1]
K01940  argininosuccinate synthase [EC:6.3.4.5]
K01755  argininosuccinate lyase [EC:4.3.2.1]
K14681  argininosuccinate lyase / amino-acid N-acetyltransferase [EC:4.3.2.1 2.3.1.1]
K01939  adenylosuccinate synthase [EC:6.3.4.4]
K01756  adenylosuccinate lyase [EC:4.3.2.2]
K18309  aspartate N-acetyltransferase [EC:2.3.1.17]
K18310  beta-citrylglutamate/N-acetylaspartylglutamate synthase [EC:6.3.1.17 6.3.2.41]
K18311  N-acetylaspartylglutamate/N-acetylaspartylglutamylglutamate synthase [EC:6.3.2.41 6.3.2.42]
K14592  glutamate carboxypeptidase II (folate hydrolase 1) [EC:3.4.17.21]
K01437  aspartoacylase [EC:3.5.1.15]
K00609  aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
K00610  aspartate carbamoyltransferase regulatory subunit
K00608  aspartate carbamoyltransferase [EC:2.1.3.2]
K01580  glutamate decarboxylase [EC:4.1.1.15]
K00823  4-aminobutyrate aminotransferase [EC:2.6.1.19]
K14268  5-aminovalerate/4-aminobutyrate aminotransferase [EC:2.6.1.48 2.6.1.19]
K07250  4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
K13524  4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22]
K16871  4-aminobutyrate---pyruvate transaminase [EC:2.6.1.96]
K00135  succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
K00139  succinate-semialdehyde dehydrogenase [EC:1.2.1.24]
K17761  succinate-semialdehyde dehydrogenase, mitochondrial [EC:1.2.1.24]
K08324  succinate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.24]
K00264  glutamate synthase (NADH) [EC:1.4.1.14]
K00265  glutamate synthase (NADPH) large chain [EC:1.4.1.13]
K00266  glutamate synthase (NADPH) small chain [EC:1.4.1.13]
K15371  glutamate dehydrogenase [EC:1.4.1.2]
K00260  glutamate dehydrogenase [EC:1.4.1.2]
K00261  glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
K00262  glutamate dehydrogenase (NADP+) [EC:1.4.1.4]
K00294  1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
K01915  glutamine synthetase [EC:6.3.1.2]
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
K11541  carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:6.3.5.5 2.1.3.2]
K01954  carbamoyl-phosphate synthase [EC:6.3.5.5]
K01955  carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
K01956  carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
K01425  glutaminase [EC:3.5.1.2]
K23265  phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
K01948  carbamoyl-phosphate synthase (ammonia) [EC:6.3.4.16]
K08590  2-oxoglutaramate amidase [EC:3.5.1.111]
K00820  glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
K00764  amidophosphoribosyltransferase [EC:2.4.2.14]
Compound
C00014  Ammonia
C00022  Pyruvate
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00036  Oxaloacetate
C00041  L-Alanine
C00042  Succinate
C00049  L-Aspartate
C00064  L-Glutamine
C00122  Fumarate
C00152  L-Asparagine
C00158  Citrate
C00169  Carbamoyl phosphate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00352  D-Glucosamine 6-phosphate
C00402  D-Aspartate
C00438  N-Carbamoyl-L-aspartate
C00940  2-Oxoglutaramate
C01042  N-Acetyl-L-aspartate
C02362  2-Oxosuccinamate
C03090  5-Phosphoribosylamine
C03406  N-(L-Arginino)succinate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03912  (S)-1-Pyrroline-5-carboxylate
C12270  N-Acetylaspartylglutamate
C20775  beta-Citryl-L-glutamate
C20776  N-Acetylaspartylglutamylglutamate
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
PMID:9687539
  Authors
Wu G
  Title
Intestinal mucosal amino acid catabolism.
  Journal
J Nutr 128:1249-52 (1998)
DOI:10.1093/jn/128.8.1249
Related
pathway
ko00010  Glycolysis / Gluconeogenesis
ko00020  Citrate cycle (TCA cycle)
ko00220  Arginine biosynthesis
ko00230  Purine metabolism
ko00240  Pyrimidine metabolism
ko00260  Glycine, serine and threonine metabolism
ko00261  Monobactam biosynthesis
ko00300  Lysine biosynthesis
ko00330  Arginine and proline metabolism
ko00340  Histidine metabolism
ko00410  beta-Alanine metabolism
ko00460  Cyanoamino acid metabolism
ko00470  D-Amino acid metabolism
ko00480  Glutathione metabolism
ko00520  Amino sugar and nucleotide sugar metabolism
ko00620  Pyruvate metabolism
ko00630  Glyoxylate and dicarboxylate metabolism
ko00650  Butanoate metabolism
ko00660  C5-Branched dibasic acid metabolism
ko00760  Nicotinate and nicotinamide metabolism
ko00770  Pantothenate and CoA biosynthesis
ko00860  Porphyrin metabolism
ko00910  Nitrogen metabolism
LinkDB

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