KEGG   PATHWAY: tfd00564
Entry
tfd00564                    Pathway                                
Name
Glycerophospholipid metabolism - Tachysurus fulvidraco (yellow catfish)
Class
Metabolism; Lipid metabolism
Pathway map
tfd00564  Glycerophospholipid metabolism
tfd00564

Module
tfd_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:tfd00564]
tfd_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:tfd00564]
tfd_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:tfd00564]
Other DBs
GO: 0006650
Organism
Tachysurus fulvidraco (yellow catfish) [GN:tfd]
Gene
113644279  gpd1l; glycerol-3-phosphate dehydrogenase 1-like protein [KO:K00006] [EC:1.1.1.8]
113647391  gpd1c; glycerol-3-phosphate dehydrogenase 1c [KO:K00006] [EC:1.1.1.8]
113654647  gpd1a; glycerol-3-phosphate dehydrogenase 1a [KO:K00006] [EC:1.1.1.8]
113639068  gpd1b; glycerol-3-phosphate dehydrogenase 1b isoform X1 [KO:K00006] [EC:1.1.1.8]
113657174  gpd2; glycerol-3-phosphate dehydrogenase, mitochondrial isoform X1 [KO:K00111] [EC:1.1.5.3]
113638980  gpam; glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
113645576  gpat2; glycerol-3-phosphate acyltransferase 2, mitochondrial isoform X2 [KO:K00629] [EC:2.3.1.15]
113638626  gpat3; glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
113639347  gpat4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
113656045  glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
113656563  agpat9l; glycerol-3-phosphate acyltransferase 3-like isoform X1 [KO:K13506] [EC:2.3.1.15]
113646568  agpat2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform X1 [KO:K13509] [EC:2.3.1.51]
113648852  agpat3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
113660714  agpat4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X1 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
113655225  agpat5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [KO:K19007] [EC:2.3.1.51]
113656708  lclat1; lysocardiolipin acyltransferase 1 isoform X1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
113655678  mboat2b; lysophospholipid acyltransferase 2b isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
113647867  mboat1; lysophospholipid acyltransferase 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
113659410  mboat2a; lysophospholipid acyltransferase 2 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
113654814  gnpat; dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
113658633  gnpat2; dihydroxyacetone phosphate acyltransferase isoform X1 [KO:K00649] [EC:2.3.1.42]
113662614  adprm; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase isoform X1 [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
113661316  plpp1a; phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
113656312  phospholipid phosphatase 1 [KO:K01080] [EC:3.1.3.4]
113648480  phospholipid phosphatase 3-like [KO:K01080] [EC:3.1.3.4]
113658703  plpp3; phospholipid phosphatase 3 isoform X1 [KO:K01080] [EC:3.1.3.4]
113645192  plpp2a; phospholipid phosphatase 2 [KO:K01080] [EC:3.1.3.4]
113657397  lpin2; phosphatidate phosphatase LPIN2 isoform X1 [KO:K15728] [EC:3.1.3.4]
113657473  phosphatidate phosphatase LPIN2 isoform X1 [KO:K15728] [EC:3.1.3.4]
113658632  phosphatidate phosphatase LPIN1-like isoform X1 [KO:K15728] [EC:3.1.3.4]
113642882  zgc:123305 isoform X4 [KO:K15728] [EC:3.1.3.4]
113651262  lpin1a; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
113655240  plpp4; phospholipid phosphatase 4 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
113639285  plpp5; phospholipid phosphatase 5 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
113654063  dgkzb; diacylglycerol kinase zeta [KO:K00901] [EC:2.7.1.107]
113637510  diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
113654273  diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
113654331  dgkh; diacylglycerol kinase eta isoform X3 [KO:K00901] [EC:2.7.1.107]
113663154  si:dkey-172j4.3; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
113637877  diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
113656883  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
113634212  dgkza; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
113635256  dgkaa; diacylglycerol kinase, alpha a [KO:K00901] [EC:2.7.1.107]
113645818  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
113654015  chpt1; cholinephosphotransferase 1 isoform X2 [KO:K00994] [EC:2.7.8.2]
113648152  cept1a; choline/ethanolaminephosphotransferase 1a [KO:K13644] [EC:2.7.8.1 2.7.8.2]
113649030  cept1b; choline/ethanolaminephosphotransferase 1b isoform X1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
113655460  si:ch211-168k14.2; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
113641488  pld2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
113637715  phospholipase D1-like isoform X1 [KO:K01115] [EC:3.1.4.4]
113660358  pld1b; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
113638823  pld3; 5'-3' exonuclease PLD3 isoform X1 [KO:K16860] [EC:3.1.4.4]
113659494  5'-3' exonuclease PLD4 [KO:K16860] [EC:3.1.4.4]
113635584  lcat; phosphatidylcholine-sterol acyltransferase [KO:K00650] [EC:2.3.1.43]
113636709  proca1; uncharacterized protein proca1 isoform X1 [KO:K01047] [EC:3.1.1.4]
113638852  pla2g1b; phospholipase A2 [KO:K01047] [EC:3.1.1.4]
113655424  pla2g12b; group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
125139380  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
113658438  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
125139714  pla2g3; group 3 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
125141113  pla2g12a; group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
113633939  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
113660382  pla2g10; group 10 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
113647521  pla2g4ab; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
113640498  cytosolic phospholipase A2 zeta-like isoform X1 [KO:K16342] [EC:3.1.1.4]
113640524  cytosolic phospholipase A2 zeta-like [KO:K16342] [EC:3.1.1.4]
113643597  pla2g4aa; cytosolic phospholipase A2 isoform X1 [KO:K16342] [EC:3.1.1.4]
113656988  pla2g6; 85/88 kDa calcium-independent phospholipase A2 isoform X2 [KO:K16343] [EC:3.1.1.4]
113644521  phospholipase B1, membrane-associated-like isoform X1 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
113641401  plb1; phospholipase B1, membrane-associated [KO:K14621] [EC:3.1.1.4 3.1.1.5]
113643343  si:dkey-177p2.18; phospholipase B1, membrane-associated isoform X3 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
125139262  phospholipase A and acyltransferase 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
125139263  phospholipase A and acyltransferase 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
113635653  phospholipase A and acyltransferase 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
113635652  phospholipase A and acyltransferase 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
113636834  lpcat2; lysophosphatidylcholine acyltransferase 2 isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
113648351  lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
113634647  lpcat1; lysophosphatidylcholine acyltransferase 1 isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
113635549  lpcat4; lysophospholipid acyltransferase LPCAT4 isoform X1 [KO:K13512] [EC:2.3.1.23 2.3.1.-]
113643470  lpcat3; lysophospholipid acyltransferase 5 isoform X1 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
113657341  lypla1; acyl-protein thioesterase 1 isoform X1 [KO:K06128] [EC:3.1.1.5]
113635894  pla2g15; group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
113661585  lypla2; acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
113653392  pnpla7b; patatin-like phospholipase domain-containing protein 7 [KO:K14676] [EC:3.1.1.5]
113640049  pnpla7a; patatin-like phospholipase domain-containing protein 7a [KO:K14676] [EC:3.1.1.5]
113649056  pnpla6; patatin-like phospholipase domain-containing protein 6 isoform X1 [KO:K14676] [EC:3.1.1.5]
113644348  gpcpd1; glycerophosphocholine phosphodiesterase GPCPD1 isoform X1 [KO:K18695] [EC:3.1.4.2]
113639946  chata; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
113652229  choline O-acetyltransferase-like [KO:K00623] [EC:2.3.1.6]
113635173  ache; acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
113652739  chkb; choline/ethanolamine kinase [KO:K14156] [EC:2.7.1.32 2.7.1.82]
113652432  chka; choline kinase alpha isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
113662539  probable phosphatase phospho1 [KO:K06124] [EC:3.1.3.75]
113638008  phospho1; probable phosphatase phospho1 [KO:K06124] [EC:3.1.3.75]
113646359  pcyt1ba; choline-phosphate cytidylyltransferase B isoform X1 [KO:K00968] [EC:2.7.7.15]
113646975  pcyt1bb; phosphate cytidylyltransferase 1B, choline b [KO:K00968] [EC:2.7.7.15]
113647122  pcyt1aa; choline-phosphate cytidylyltransferase A isoform X1 [KO:K00968] [EC:2.7.7.15]
113640695  pcyt1ab; phosphate cytidylyltransferase 1A, choline b isoform X1 [KO:K00968] [EC:2.7.7.15]
113641912  selenoi; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
113651955  zgc:113516; ethanolamine kinase 2 isoform X1 [KO:K00894] [EC:2.7.1.82]
113647865  etnk2; ethanolamine kinase 2 isoform X1 [KO:K00894] [EC:2.7.1.82]
113651574  etnk1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
113639578  ethanolamine-phosphate cytidylyltransferase-like [KO:K00967] [EC:2.7.7.14]
113651889  pcyt2; ethanolamine-phosphate cytidylyltransferase isoform X2 [KO:K00967] [EC:2.7.7.14]
113660046  pmt; phosphoethanolamine methyltransferase isoform X1 [KO:K05929] [EC:2.1.1.103]
125138334  etnppl; ethanolamine-phosphate phospho-lyase isoform X2 [KO:K14286] [EC:4.2.3.2]
113650647  pemt; phosphatidylethanolamine N-methyltransferase isoform X1 [KO:K00551] [EC:2.1.1.17 2.1.1.71]
113653302  cds1; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
113657318  cds2; phosphatidate cytidylyltransferase 2 isoform X1 [KO:K00981] [EC:2.7.7.41]
113654421  pla1a; phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
113661614  ptdss1b; phosphatidylserine synthase 1 isoform X1 [KO:K08729] [EC:2.7.8.-]
113634379  ptdss1a; phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
113654023  ptdss2; phosphatidylserine synthase 2 isoform X1 [KO:K08730] [EC:2.7.8.29]
113641470  pisd; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
113638967  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial isoform X1 [KO:K00995] [EC:2.7.8.5]
113659275  crls1; cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
113650924  tafazzin; tafazzin isoform X1 [KO:K13511] [EC:2.3.1.-]
113655644  lpgat1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 isoform X1 [KO:K13514] [EC:2.3.1.-]
113639497  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
113659061  mboat7; lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
tfd00010  Glycolysis / Gluconeogenesis
tfd00260  Glycine, serine and threonine metabolism
tfd00561  Glycerolipid metabolism
tfd00562  Inositol phosphate metabolism
tfd00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
tfd00565  Ether lipid metabolism
tfd00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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