Entry |
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Symbol |
MAM-D, IMDH3
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Name |
3-isopropylmalate/methylthioalkylmalate dehydrogenase [EC: 1.1.1.85 1.1.1.-]
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Pathway |
map00290 | Valine, leucine and isoleucine biosynthesis |
map01110 | Biosynthesis of secondary metabolites |
map01210 | 2-Oxocarboxylic acid metabolism |
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Reaction |
R04426 | (2R,3S)-3-isopropylmalate:NAD+ oxidoreductase |
R08621 | 3-(2'-methylthio)ethylmalate:NAD+ oxidoreductase (decarboxylating) |
R08625 | 3-(3'-methylthio)propylmalate:NAD+ oxidoreductase (decarboxylating) |
R08629 | 3-(4'-methylthio)butylmalate:NAD+ oxidoreductase (decarboxylating) |
R08636 | 3-(5'-methylthio)pentylmalate:NAD+ oxidoreductase (decarboxylating) |
R08642 | 3-(6'-methylthio)hexylmalate:NAD+ oxidoreductase (decarboxylating) |
R08646 | 3-(7'-methylthio)heptylmalate:NAD+ oxidoreductase (decarboxylating) |
R10052 | (2R,3S)-3-isopropylmalate:NAD+ oxidoreductase |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
K21360 MAM-D, IMDH3; 3-isopropylmalate/methylthioalkylmalate dehydrogenase
09110 Biosynthesis of other secondary metabolites
00966 Glucosinolate biosynthesis
K21360 MAM-D, IMDH3; 3-isopropylmalate/methylthioalkylmalate dehydrogenase
Enzymes [BR:ko01000]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
K21360 MAM-D, IMDH3; 3-isopropylmalate/methylthioalkylmalate dehydrogenase
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Other DBs |
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Genes |
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Reference |
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Authors |
He Y, Mawhinney TP, Preuss ML, Schroeder AC, Chen B, Abraham L, Jez JM, Chen S |
Title |
A redox-active isopropylmalate dehydrogenase functions in the biosynthesis of glucosinolates and leucine in Arabidopsis. |
Journal |
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Sequence |
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LinkDB |
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