KEGG   ORTHOLOGY: K21360
Entry
K21360                      KO                                     
Symbol
MAM-D, IMDH3
Name
3-isopropylmalate/methylthioalkylmalate dehydrogenase [EC:1.1.1.85 1.1.1.-]
Pathway
map00290  Valine, leucine and isoleucine biosynthesis
map00966  Glucosinolate biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01210  2-Oxocarboxylic acid metabolism
Reaction
R04426  (2R,3S)-3-isopropylmalate:NAD+ oxidoreductase
R08621  3-(2'-methylthio)ethylmalate:NAD+ oxidoreductase (decarboxylating)
R08625  3-(3'-methylthio)propylmalate:NAD+ oxidoreductase (decarboxylating)
R08629  3-(4'-methylthio)butylmalate:NAD+ oxidoreductase (decarboxylating)
R08636  3-(5'-methylthio)pentylmalate:NAD+ oxidoreductase (decarboxylating)
R08642  3-(6'-methylthio)hexylmalate:NAD+ oxidoreductase (decarboxylating)
R08646  3-(7'-methylthio)heptylmalate:NAD+ oxidoreductase (decarboxylating)
R10052  (2R,3S)-3-isopropylmalate:NAD+ oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    K21360  MAM-D, IMDH3; 3-isopropylmalate/methylthioalkylmalate dehydrogenase
  09110 Biosynthesis of other secondary metabolites
   00966 Glucosinolate biosynthesis
    K21360  MAM-D, IMDH3; 3-isopropylmalate/methylthioalkylmalate dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.85  3-isopropylmalate dehydrogenase
     K21360  MAM-D, IMDH3; 3-isopropylmalate/methylthioalkylmalate dehydrogenase
Other DBs
GO: 0003862 0103093
Genes
ATH: AT5G14200(IMD1)
CRB: 17884309
CSAT: 104735438 104769651
EUS: EUTSA_v10013695mg
BRP: 103850918
BNA: 106367226
Reference
  Authors
He Y, Mawhinney TP, Preuss ML, Schroeder AC, Chen B, Abraham L, Jez JM, Chen S
  Title
A redox-active isopropylmalate dehydrogenase functions in the biosynthesis of glucosinolates and leucine in Arabidopsis.
  Journal
Plant J 60:679-90 (2009)
DOI:10.1111/j.1365-313X.2009.03990.x
  Sequence
[ath:AT5G14200]
LinkDB

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