KEGG   PATHWAY: sjo04150
Entry
sjo04150                    Pathway                                
Name
mTOR signaling pathway - Scomber japonicus (chub mackerel)
Description
The mammalian (mechanistic) target of rapamycin (mTOR) is a highly conserved serine/threonine protein kinase, which exists in two complexes termed mTOR complex 1 (mTORC1) and 2 (mTORC2). mTORC1 contains mTOR, Raptor, PRAS40, Deptor, mLST8, Tel2 and Tti1. mTORC1 is activated by the presence of growth factors, amino acids, energy status, stress and oxygen levels to regulate several biological processes, including lipid metabolism, autophagy, protein synthesis and ribosome biogenesis. On the other hand, mTORC2, which consists of mTOR, mSin1, Rictor, Protor, Deptor, mLST8, Tel2 and Tti1, responds to growth factors and controls cytoskeletal organization, metabolism and survival.
Class
Environmental Information Processing; Signal transduction
Pathway map
sjo04150  mTOR signaling pathway
sjo04150

Organism
Scomber japonicus (chub mackerel) [GN:sjo]
Gene
128359487  slc7a5; large neutral amino acids transporter small subunit 1 [KO:K13780]
128356958  large neutral amino acids transporter small subunit 1-like [KO:K13780]
128375586  4F2 cell-surface antigen heavy chain-like [KO:K06519]
128360267  si:dkey-202g17.3; 4F2 cell-surface antigen heavy chain [KO:K06519]
128383307  slc3a2a; solute carrier family 3 member 2a [KO:K06519]
128379767  slc38a9; sodium-coupled neutral amino acid transporter 9 [KO:K14995]
128371084  V-type proton ATPase catalytic subunit A-like [KO:K02145] [EC:7.1.2.2]
128382482  atp6v1ab; V-type proton ATPase catalytic subunit A [KO:K02145] [EC:7.1.2.2]
128372749  atp6v1ba; V-type proton ATPase subunit B, kidney isoform [KO:K02147]
128374977  atp6v1c2; V-type proton ATPase subunit C 1-B [KO:K02148]
128366036  atp6v1c1a; V-type proton ATPase subunit C 1-A [KO:K02148]
128373668  atp6v1c1b; V-type proton ATPase subunit C 1-B [KO:K02148]
128376665  atp6v1d; V-type proton ATPase subunit D [KO:K02149]
128358391  atp6v1e1a; V-type proton ATPase subunit E 1a [KO:K02150]
128385323  atp6v1e1b; V-type proton ATPase subunit E 1 [KO:K02150]
128353297  atp6v1f; V-type proton ATPase subunit F [KO:K02151]
128380344  atp6v1g1; V-type proton ATPase subunit G 1 [KO:K02152]
128369071  atp6v1h; V-type proton ATPase subunit H [KO:K02144]
128361004  lamtor1; ragulator complex protein LAMTOR1 [KO:K20397]
128366301  lamtor2; ragulator complex protein LAMTOR2 [KO:K20398]
128375485  lamtor3; ragulator complex protein LAMTOR3 [KO:K04370]
128385207  lamtor4; ragulator complex protein LAMTOR4 [KO:K20399]
128357854  lamtor5; ragulator complex protein LAMTOR5 [KO:K16344]
128365946  flcn; folliculin isoform X1 [KO:K09594]
128371916  fnip1; folliculin-interacting protein 1 isoform X1 [KO:K20400]
128371913  rraga; ras-related GTP-binding protein A [KO:K16185]
128375103  rragd; ras-related GTP-binding protein D [KO:K16186]
128366586  rragca; ras-related GTP binding Ca [KO:K16186]
128373730  rragcb; ras-related GTP binding Cb [KO:K16186]
128374640  sesn2; sestrin-2 isoform X1 [KO:K20394]
128365459  castor1; cytosolic arginine sensor for mTORC1 subunit 1 [KO:K23080]
128371923  castor2; cytosolic arginine sensor for mTORC1 subunit 2 [KO:K23081]
128366672  mios; GATOR complex protein MIOS [KO:K20407]
128365757  seh1l; nucleoporin SEH1 [KO:K14299]
128381295  wdr24; GATOR complex protein WDR24 [KO:K20408]
128359483  wdr59; GATOR complex protein WDR59 isoform X1 [KO:K20409]
128356229  sec13; protein SEC13 homolog [KO:K14004]
128368489  depdc5; GATOR complex protein DEPDC5 isoform X1 [KO:K20404]
128355094  nprl2; GATOR complex protein NPRL2 [KO:K20405]
128378519  nprl3; GATOR complex protein NPRL3 isoform X1 [KO:K20406]
128380407  skp2; S-phase kinase-associated protein 2 [KO:K03875]
128382283  rnf152; E3 ubiquitin-protein ligase rnf152 [KO:K15705] [EC:2.3.2.27]
128367812  rptor; regulatory-associated protein of mTOR isoform X1 [KO:K07204]
128378941  akt1s1; uncharacterized protein akt1s1 [KO:K16184]
128356865  mtor; serine/threonine-protein kinase mTOR isoform X1 [KO:K07203] [EC:2.7.11.1]
128355207  si:dkeyp-97e7.9; LOW QUALITY PROTEIN: DEP domain-containing mTOR-interacting protein [KO:K20402]
128366806  deptor; DEP domain-containing mTOR-interacting protein isoform X1 [KO:K20402]
128381275  mlst8; target of rapamycin complex subunit lst8 [KO:K08266]
128381918  telo2; telomere length regulation protein TEL2 homolog [KO:K11137]
128357347  tti1; TELO2-interacting protein 1 homolog [KO:K20403]
128380733  clip1b; CAP-Gly domain-containing linker protein 1 [KO:K10421]
128365451  clip1a; CAP-Gly domain-containing linker protein 1 isoform X1 [KO:K10421]
128373975  growth factor receptor-bound protein 10-like [KO:K20064]
128365983  grb10b; growth factor receptor-bound protein 10 isoform X1 [KO:K20064]
128369396  lpin2; phosphatidate phosphatase LPIN2 isoform X1 [KO:K15728] [EC:3.1.3.4]
128376744  phosphatidate phosphatase LPIN1-like [KO:K15728] [EC:3.1.3.4]
128382107  LOW QUALITY PROTEIN: phosphatidate phosphatase LPIN2-like [KO:K15728] [EC:3.1.3.4]
128355575  lpin1a; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
128382829  LOW QUALITY PROTEIN: phosphatidate phosphatase LPIN2-like [KO:K15728] [EC:3.1.3.4]
128356139  phosphatidate phosphatase LPIN2-like [KO:K15728] [EC:3.1.3.4]
128380210  ulk1b; serine/threonine-protein kinase ULK1 [KO:K21357] [EC:2.7.11.1]
128364485  ulk1a; serine/threonine-protein kinase ULK1a [KO:K21357] [EC:2.7.11.1]
128360241  ulk2; serine/threonine-protein kinase ULK2 isoform X1 [KO:K08269] [EC:2.7.11.1]
128380209  eukaryotic translation initiation factor 4E-binding protein 1-like [KO:K07205]
128365300  eukaryotic translation initiation factor 4E-binding protein 1-like [KO:K07205]
128362557  eif4ea; eukaryotic translation initiation factor 4E-1A [KO:K03259]
128369307  eif4e2; eukaryotic translation initiation factor 4E type 2 isoform X1 [KO:K03259]
128375072  eif4eb; eukaryotic translation initiation factor 4eb [KO:K03259]
128372706  eif4e1c; eukaryotic translation initiation factor 4E family member 1c [KO:K03259]
128383768  eif4e2rs1; eukaryotic translation initiation factor 4E family member 2 related sequence 1 isoform X1 [KO:K03259]
128371140  rps6kb1a; ribosomal protein S6 kinase beta-1 [KO:K04688] [EC:2.7.11.1]
128371485  ribosomal protein S6 kinase beta-2-like [KO:K04688] [EC:2.7.11.1]
128360431  rps6kb1b; ribosomal protein S6 kinase beta-1 [KO:K04688] [EC:2.7.11.1]
128354980  eif4ba; eukaryotic translation initiation factor 4Ba isoform X1 [KO:K03258]
128368460  rps6; 40S ribosomal protein S6 [KO:K02991]
128379179  strada; STE20-related kinase adapter protein alpha [KO:K08271]
128354064  stradb; STE20-related kinase adapter protein beta [KO:K17532]
128368988  stk11; serine/threonine-protein kinase STK11 [KO:K07298] [EC:2.7.11.1]
128363384  cab39l1; calcium binding protein 39, like 1 [KO:K08272]
128354089  cab39l; calcium-binding protein 39-like [KO:K08272]
128360677  cab39; calcium-binding protein 39 [KO:K08272]
128380222  prkaa1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 [KO:K07198] [EC:2.7.11.31]
128362104  prkaa2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X1 [KO:K07198] [EC:2.7.11.31]
128380427  tsc1b; TSC complex subunit 1b [KO:K07206]
128354708  hamartin-like [KO:K07206]
128381140  tsc2; tuberin isoform X1 [KO:K07207]
128361510  tbc1d7; TBC1 domain family member 7 [KO:K20396]
128368934  rheb; GTP-binding protein Rheb [KO:K07208]
128356059  rhebl1; ras homolog, mTORC1 binding like 1 [KO:K07208]
128381378  ddit4; DNA damage-inducible transcript 4 protein [KO:K08270]
128373022  DNA damage-inducible transcript 4 protein-like [KO:K08270]
128357061  wnt1; protein Wnt-1 [KO:K03209]
128357873  protein Wnt-2b-A-like [KO:K00182]
128358579  wnt2; protein Wnt-2 [KO:K00182]
128355004  protein Wnt-2b-A-like [KO:K00182]
128368829  wnt3a; protein Wnt-3a [KO:K00312]
128381453  LOW QUALITY PROTEIN: proto-oncogene Wnt-3-like [KO:K00312]
128365858  wnt4b; wingless-type MMTV integration site family, member 4b [KO:K00408]
128356273  wnt4; protein Wnt-4a [KO:K00408]
128356859  wnt5a; protein Wnt-5a [KO:K00444]
128385231  wnt5b; protein Wnt-5b [KO:K00444]
128367925  wnt6b; protein Wnt-6 [KO:K00445]
128358366  wnt7bb; protein Wnt-7b isoform X1 [KO:K00572]
128353389  wnt7ba; protein Wnt-7b [KO:K00572]
128355468  wnt7aa; wingless-type MMTV integration site family, member 7Aa [KO:K00572]
128357063  protein Wnt-7a [KO:K00572]
128363070  protein Wnt-8a-like [KO:K00714]
128363080  protein Wnt-8a-like [KO:K00714]
128373411  wnt8b; protein Wnt-8b [KO:K00714]
128369222  wnt9a; LOW QUALITY PROTEIN: protein Wnt-9a [KO:K01064]
128379047  wnt9b; protein Wnt-9b [KO:K01064]
128357466  wnt10b; protein Wnt-10b [KO:K01357]
128367632  wnt10a; protein Wnt-10a [KO:K01357]
128371601  wnt11; protein Wnt-11 [KO:K01384]
128385155  wnt16; protein Wnt-16 [KO:K01558]
128354260  frizzled-7-like [KO:K02432]
128365961  fzd1; frizzled-1 [KO:K02432]
128367746  frizzled-7-A-like [KO:K02432]
128378376  fzd2; frizzled-2 isoform X1 [KO:K02235]
128362928  fzd3b; frizzled-3b [KO:K02329]
128376937  fzd3a; frizzled-3a isoform X1 [KO:K02329]
128360944  fzd4; frizzled-4 [KO:K02354]
128369414  frizzled-8-like [KO:K02375]
128382460  fzd8a; frizzled-8a [KO:K02375]
128367486  fzd5; frizzled-5 [KO:K02375]
128366389  fzd6; frizzled-6 [KO:K02376]
128364521  fzd10; frizzled-10 [KO:K02842]
128359778  fzd9b; frizzled-9b [KO:K02842]
128353161  lrp6; LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 6 [KO:K03068]
128359515  lrp5; LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 5 [KO:K03068]
128368884  segment polarity protein dishevelled homolog DVL-3-like isoform X1 [KO:K02353]
128360057  segment polarity protein dishevelled homolog DVL-3-like [KO:K02353]
128383860  dvl2; segment polarity protein dishevelled homolog DVL-2 [KO:K02353]
128357207  segment polarity protein dishevelled homolog DVL-1-like isoform X1 [KO:K02353]
128368261  gsk3ba; glycogen synthase kinase-3 beta isoform X1 [KO:K03083] [EC:2.7.11.26]
128374748  tnfa; tumor necrosis factor a (TNF superfamily, member 2) [KO:K03156]
128365852  tnfrsf1a; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
128364098  ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
128363077  insb; preproinsulin b [KO:K04526]
128371064  insulin [KO:K04526]
128371442  insulin-like [KO:K04526]
128353374  igf1; insulin-like growth factor I [KO:K05459]
128357012  igf3; insulin-like growth factor 3 [KO:K05459]
128369270  insulin receptor-like [KO:K04527] [EC:2.7.10.1]
128362171  insrb; insulin receptor b [KO:K04527] [EC:2.7.10.1]
128358344  igf1ra; insulin-like growth factor 1a receptor [KO:K05087] [EC:2.7.10.1]
128356204  igf1rb; insulin-like growth factor 1b receptor [KO:K05087] [EC:2.7.10.1]
128366075  grb2a; growth factor receptor-bound protein 2a [KO:K04364]
128378768  grb2b; growth factor receptor-bound protein 2b [KO:K04364]
128375047  sos2; son of sevenless homolog 2 [KO:K03099]
128375833  LOW QUALITY PROTEIN: son of sevenless homolog 1-like [KO:K03099]
128359229  hrasa; HRas proto-oncogene, GTPase a [KO:K02833]
128358543  kras; GTPase KRas isoform X1 [KO:K07827]
128378744  zgc:55558; GTPase KRas isoform X1 [KO:K07827]
128353393  braf; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
128357963  raf1a; raf-1 proto-oncogene, serine/threonine kinase a isoform X1 [KO:K04366] [EC:2.7.11.1]
128359279  map2k1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
128361721  map2k2a; dual specificity mitogen-activated protein kinase kinase 2a [KO:K04369] [EC:2.7.12.2]
128364483  mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
128378997  mapk3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
128362534  rps6kal; ribosomal protein S6 kinase alpha-6 [KO:K04373] [EC:2.7.11.1]
128375828  ribosomal protein S6 kinase alpha-1 isoform X1 [KO:K04373] [EC:2.7.11.1]
128361738  rps6ka2; ribosomal protein S6 kinase alpha-2 [KO:K04373] [EC:2.7.11.1]
128370926  si:ch211-284e13.4; insulin receptor substrate 1-B [KO:K16172]
128383280  si:ch73-335l21.1; insulin receptor substrate 1-B isoform X1 [KO:K16172]
128362253  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
128362334  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
128368529  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
128369279  pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
128380785  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
128368727  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
128360701  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
128361329  pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
128384054  zgc:158659; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
128357418  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
128381593  ptenb; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
128372599  ptena; phosphatase and tensin homolog A isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
128381694  pdpk1b; 3-phosphoinositide dependent protein kinase 1b [KO:K06276] [EC:2.7.11.1]
128374961  akt3b; LOW QUALITY PROTEIN: RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
128375416  akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
128360590  akt2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
128371932  RAC-beta serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
128372947  akt3a; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
128381630  inhibitor of nuclear factor kappa-B kinase subunit alpha-like [KO:K04467] [EC:2.7.11.10]
128372978  inhibitor of nuclear factor kappa-B kinase subunit alpha-like isoform X1 [KO:K04467] [EC:2.7.11.10]
128380217  mapkap1; target of rapamycin complex 2 subunit MAPKAP1 [KO:K20410]
128379721  rapamycin-insensitive companion of mTOR-like [KO:K08267]
128365301  rapamycin-insensitive companion of mTOR-like isoform X1 [KO:K08267]
128353205  proline-rich protein 5-like [KO:K20411]
128358466  prr5a; proline-rich protein 5a [KO:K20411]
128357844  rhoab; rho-related GTP-binding protein RhoA-B [KO:K04513]
128357883  rho-related GTP-binding protein RhoA-D [KO:K04513]
128357884  rho-related GTP-binding protein RhoA-C-like [KO:K04513]
128354934  rho-related GTP-binding protein RhoA-D-like [KO:K04513]
128356196  transforming protein RhoA [KO:K04513]
128356793  rho-related GTP-binding protein RhoA-C [KO:K04513]
128372880  protein kinase C alpha type-like [KO:K02677] [EC:2.7.11.13]
128378482  prkcab; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
128380002  protein kinase C beta type-like [KO:K19662] [EC:2.7.11.13]
128378636  protein kinase C beta type [KO:K19662] [EC:2.7.11.13]
128365943  prkcg; protein kinase C alpha type [KO:K19663] [EC:2.7.11.13]
128376717  sgk1; serine/threonine-protein kinase Sgk1 isoform X1 [KO:K13302] [EC:2.7.11.1]
128365918  sgk2b; serine/threonine-protein kinase Sgk2b [KO:K13302] [EC:2.7.11.1]
128373764  si:ch211-195b13.1; STKc_SGK domain-containing protein [KO:K13302] [EC:2.7.11.1]
Compound
C00020  AMP
C00062  L-Arginine
C00123  L-Leucine
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
PMID:27304501
  Authors
Kennedy BK, Lamming DW
  Title
The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging.
  Journal
Cell Metab 23:990-1003 (2016)
DOI:10.1016/j.cmet.2016.05.009
Reference
PMID:24556838
  Authors
Shimobayashi M, Hall MN
  Title
Making new contacts: the mTOR network in metabolism and signalling crosstalk.
  Journal
Nat Rev Mol Cell Biol 15:155-62 (2014)
DOI:10.1038/nrm3757
Reference
PMID:25242279
  Authors
Huang K, Fingar DC
  Title
Growing knowledge of the mTOR signaling network.
  Journal
Semin Cell Dev Biol 36:79-90 (2014)
DOI:10.1016/j.semcdb.2014.09.011
Reference
PMID:26269525
  Authors
Bockaert J, Marin P
  Title
mTOR in Brain Physiology and Pathologies.
  Journal
Physiol Rev 95:1157-87 (2015)
DOI:10.1152/physrev.00038.2014
Reference
PMID:26185979
  Authors
Caron A, Richard D, Laplante M
  Title
The Roles of mTOR Complexes in Lipid Metabolism.
  Journal
Annu Rev Nutr 35:321-48 (2015)
DOI:10.1146/annurev-nutr-071714-034355
Reference
PMID:26658722
  Authors
Shimobayashi M, Hall MN
  Title
Multiple amino acid sensing inputs to mTORC1.
  Journal
Cell Res 26:7-20 (2016)
DOI:10.1038/cr.2015.146
Reference
PMID:24698685
  Authors
Bar-Peled L, Sabatini DM
  Title
Regulation of mTORC1 by amino acids.
  Journal
Trends Cell Biol 24:400-6 (2014)
DOI:10.1016/j.tcb.2014.03.003
Reference
PMID:26046644
  Authors
Fingar DC
  Title
Rag Ubiquitination Recruits a GATOR1: Attenuation of Amino Acid-Induced mTORC1 Signaling.
  Journal
Mol Cell 58:713-5 (2015)
DOI:10.1016/j.molcel.2015.05.029
Reference
PMID:26700098
  Authors
Cai H, Dong LQ, Liu F
  Title
Recent Advances in Adipose mTOR Signaling and Function: Therapeutic Prospects.
  Journal
Trends Pharmacol Sci 37:303-17 (2016)
DOI:10.1016/j.tips.2015.11.011
Reference
PMID:24842496
  Authors
Eyre TA, Collins GP, Goldstone AH, Cwynarski K
  Title
Time now to TORC the TORC? New developments in mTOR pathway inhibition in lymphoid malignancies.
  Journal
Br J Haematol 166:336-51 (2014)
DOI:10.1111/bjh.12945
Reference
PMID:23465396
  Authors
Jewell JL, Guan KL
  Title
Nutrient signaling to mTOR and cell growth.
  Journal
Trends Biochem Sci 38:233-42 (2013)
DOI:10.1016/j.tibs.2013.01.004
Reference
PMID:23421405
  Authors
Wood TL, Bercury KK, Cifelli SE, Mursch LE, Min J, Dai J, Macklin WB
  Title
mTOR: a link from the extracellular milieu to transcriptional regulation of oligodendrocyte development.
  Journal
ASN Neuro 5:e00108 (2013)
DOI:10.1042/AN20120092
Reference
PMID:23694989
  Authors
Kim SG, Buel GR, Blenis J
  Title
Nutrient regulation of the mTOR complex 1 signaling pathway.
  Journal
Mol Cells 35:463-73 (2013)
DOI:10.1007/s10059-013-0138-2
Reference
PMID:19812304
  Authors
Laplante M, Sabatini DM
  Title
mTOR signaling at a glance.
  Journal
J Cell Sci 122:3589-94 (2009)
DOI:10.1242/jcs.051011
Reference
PMID:16756488
  Authors
Alessi DR, Sakamoto K, Bayascas JR
  Title
LKB1-dependent signaling pathways.
  Journal
Annu Rev Biochem 75:137-63 (2006)
DOI:10.1146/annurev.biochem.75.103004.142702
Reference
PMID:27027448
  Authors
Dan HC, Antonia RJ, Baldwin AS
  Title
PI3K/Akt promotes feedforward mTORC2 activation through IKKalpha.
  Journal
Oncotarget 7:21064-75 (2016)
DOI:10.18632/oncotarget.8383
Reference
PMID:28283069
  Authors
Saxton RA, Sabatini DM
  Title
mTOR Signaling in Growth, Metabolism, and Disease.
  Journal
Cell 168:960-976 (2017)
DOI:10.1016/j.cell.2017.02.004
Related
pathway
sjo00561  Glycerolipid metabolism
sjo04010  MAPK signaling pathway
sjo04140  Autophagy - animal
sjo04810  Regulation of actin cytoskeleton
sjo04910  Insulin signaling pathway
KO pathway
ko04150   
LinkDB

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