KEGG   PATHWAY: rsz00270
Entry
rsz00270                    Pathway                                
Name
Cysteine and methionine metabolism - Raphanus sativus (radish)
Description
Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034].
Class
Metabolism; Amino acid metabolism
Pathway map
rsz00270  Cysteine and methionine metabolism
rsz00270

Module
rsz_M00021  Cysteine biosynthesis, serine => cysteine [PATH:rsz00270]
rsz_M00034  Methionine salvage pathway [PATH:rsz00270]
rsz_M00368  Ethylene biosynthesis, methionine => ethylene [PATH:rsz00270]
Other DBs
GO: 0006534 0006555
Organism
Raphanus sativus (radish) [GN:rsz]
Gene
108805350  serine acetyltransferase 2 [KO:K00640] [EC:2.3.1.30]
108812711  serine acetyltransferase 1, chloroplastic [KO:K00640] [EC:2.3.1.30]
108805414  serine acetyltransferase 1, chloroplastic [KO:K00640] [EC:2.3.1.30]
108822823  serine acetyltransferase 1, chloroplastic [KO:K00640] [EC:2.3.1.30]
108828608  serine acetyltransferase 5 [KO:K00640] [EC:2.3.1.30]
108861934  serine acetyltransferase 3, mitochondrial [KO:K00640] [EC:2.3.1.30]
108843868  serine acetyltransferase 5 [KO:K00640] [EC:2.3.1.30]
130503721  serine acetyltransferase 5 [KO:K00640] [EC:2.3.1.30]
108827680  bifunctional cystathionine gamma-lyase/cysteine synthase [KO:K01738] [EC:2.5.1.47]
108830500  cysteine synthase, mitochondrial [KO:K01738] [EC:2.5.1.47]
108834645  cysteine synthase [KO:K01738] [EC:2.5.1.47]
108805389  cysteine synthase 2 [KO:K01738] [EC:2.5.1.47]
108834941  bifunctional L-3-cyanoalanine synthase/cysteine synthase D2-like isoform X1 [KO:K01738] [EC:2.5.1.47]
108861860  bifunctional L-3-cyanoalanine synthase/cysteine synthase D1 isoform X2 [KO:K01738] [EC:2.5.1.47]
108861861  bifunctional L-3-cyanoalanine synthase/cysteine synthase D1 isoform X1 [KO:K01738] [EC:2.5.1.47]
108810348  bifunctional L-3-cyanoalanine synthase/cysteine synthase D2 [KO:K01738] [EC:2.5.1.47]
108835881  bifunctional L-3-cyanoalanine synthase/cysteine synthase D1 [KO:K01738] [EC:2.5.1.47]
108823519  bifunctional L-3-cyanoalanine synthase/cysteine synthase D2-like [KO:K01738] [EC:2.5.1.47]
108854213  cysteine synthase, chloroplastic/chromoplastic [KO:K01738] [EC:2.5.1.47]
108841880  cysteine synthase [KO:K01738] [EC:2.5.1.47]
108820082  cysteine synthase [KO:K01738] [EC:2.5.1.47]
130494575  bifunctional L-3-cyanoalanine synthase/cysteine synthase D2 isoform X1 [KO:K01738] [EC:2.5.1.47]
108848483  cysteine synthase, mitochondrial-like isoform X1 [KO:K01738] [EC:2.5.1.47]
108863440  LOW QUALITY PROTEIN: bifunctional L-3-cyanoalanine synthase/cysteine synthase C1, mitochondrial [KO:K13034] [EC:2.5.1.47 4.4.1.9]
108855811  bifunctional L-3-cyanoalanine synthase/cysteine synthase C1, mitochondrial [KO:K13034] [EC:2.5.1.47 4.4.1.9]
108831221  cystathionine beta-lyase, chloroplastic [KO:K01760] [EC:4.4.1.13]
130511770  cystathionine beta-lyase, chloroplastic [KO:K01760] [EC:4.4.1.13]
108821536  cystine lyase CORI3 [KO:K21623] [EC:4.4.1.35]
108857084  homocysteine S-methyltransferase 3 [KO:K00547] [EC:2.1.1.10]
108830539  selenocysteine Se-methyltransferase [KO:K00547] [EC:2.1.1.10]
108833428  homocysteine S-methyltransferase 1 [KO:K00547] [EC:2.1.1.10]
108817566  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1 [KO:K00549] [EC:2.1.1.14]
108839717  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1 [KO:K00549] [EC:2.1.1.14]
108847402  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1 [KO:K00549] [EC:2.1.1.14]
108863130  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 2 [KO:K00549] [EC:2.1.1.14]
108847732  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 3, chloroplastic [KO:K00549] [EC:2.1.1.14]
108814831  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 3, chloroplastic [KO:K00549] [EC:2.1.1.14]
130501733  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1 [KO:K00549] [EC:2.1.1.14]
108862000  S-adenosylmethionine synthase 2 [KO:K00789] [EC:2.5.1.6]
108808970  S-adenosylmethionine synthase 2 [KO:K00789] [EC:2.5.1.6]
108811687  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
108827991  S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
108811774  S-adenosylmethionine synthase 2 [KO:K00789] [EC:2.5.1.6]
108855363  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
108845760  S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
108847942  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
130501059  S-adenosylmethionine synthase 2 [KO:K00789] [EC:2.5.1.6]
130502303  S-adenosylmethionine synthase 2-like [KO:K00789] [EC:2.5.1.6]
130502460  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
130506786  S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
130507325  S-adenosylmethionine synthase 2-like [KO:K00789] [EC:2.5.1.6]
130507345  S-adenosylmethionine synthase-like [KO:K00789] [EC:2.5.1.6]
108845582  S-adenosylmethionine decarboxylase proenzyme 4 [KO:K01611] [EC:4.1.1.50]
108861791  S-adenosylmethionine decarboxylase proenzyme 3 [KO:K01611] [EC:4.1.1.50]
108812509  S-adenosylmethionine decarboxylase proenzyme 3 [KO:K01611] [EC:4.1.1.50]
108845606  S-adenosylmethionine decarboxylase proenzyme 2-like [KO:K01611] [EC:4.1.1.50]
108833562  S-adenosylmethionine decarboxylase proenzyme 2 [KO:K01611] [EC:4.1.1.50]
108816169  S-adenosylmethionine decarboxylase proenzyme 4 [KO:K01611] [EC:4.1.1.50]
108846828  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
130494338  S-adenosylmethionine decarboxylase proenzyme 3-like [KO:K01611] [EC:4.1.1.50]
130494546  S-adenosylmethionine decarboxylase proenzyme 3-like [KO:K01611] [EC:4.1.1.50]
130501339  S-adenosylmethionine decarboxylase proenzyme 1-like [KO:K01611] [EC:4.1.1.50]
108842787  spermine synthase [KO:K00797] [EC:2.5.1.16]
108809148  spermidine synthase 1 [KO:K00797] [EC:2.5.1.16]
108823778  spermine synthase isoform X1 [KO:K00797] [EC:2.5.1.16]
108833037  spermidine synthase 1 [KO:K00797] [EC:2.5.1.16]
108816722  nicotianamine synthase 1-like [KO:K05953] [EC:2.5.1.43]
108850421  nicotianamine synthase 1-like [KO:K05953] [EC:2.5.1.43]
108845407  nicotianamine synthase 3 [KO:K05953] [EC:2.5.1.43]
108841297  nicotianamine synthase 2-like [KO:K05953] [EC:2.5.1.43]
108840442  nicotianamine synthase 2 [KO:K05953] [EC:2.5.1.43]
108843450  nicotianamine synthase 2-like [KO:K05953] [EC:2.5.1.43]
108844640  nicotianamine synthase 1 [KO:K05953] [EC:2.5.1.43]
108860857  nicotianamine synthase 2-like [KO:K05953] [EC:2.5.1.43]
130507416  nicotianamine synthase 2-like [KO:K05953] [EC:2.5.1.43]
108822950  5'-methylthioadenosine nucleosidase [KO:K01244] [EC:3.2.2.16]
108823051  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [KO:K01244] [EC:3.2.2.16]
130498902  5'-methylthioadenosine nucleosidase [KO:K01244] [EC:3.2.2.16]
130499137  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [KO:K01244] [EC:3.2.2.16]
130506257  5'-methylthioadenosine nucleosidase-like [KO:K01244] [EC:3.2.2.16]
108815336  methylthioribose kinase isoform X2 [KO:K00899] [EC:2.7.1.100]
130505848  methylthioribose kinase-like [KO:K00899] [EC:2.7.1.100]
108856582  methylthioribose-1-phosphate isomerase [KO:K08963] [EC:5.3.1.23]
108818799  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 isoform X1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
108819495  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
108828440  acireductone dioxygenase 4 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
108842750  acireductone dioxygenase 2 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
108842751  acireductone dioxygenase 2 isoform X1 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
108818209  uncharacterized protein LOC108818209 [KO:K23977] [EC:2.6.1.117]
108835078  S-alkyl-thiohydroximate lyase SUR1 [KO:K00815] [EC:2.6.1.5]
108820767  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
108839484  probable aminotransferase TAT4 [KO:K00815] [EC:2.6.1.5]
108846081  probable aminotransferase TAT3 [KO:K00815] [EC:2.6.1.5]
108807388  LOW QUALITY PROTEIN: tyrosine aminotransferase [KO:K00815] [EC:2.6.1.5]
108810163  probable aminotransferase TAT3 [KO:K00815] [EC:2.6.1.5]
108818723  probable aminotransferase TAT4 [KO:K00815] [EC:2.6.1.5]
108836108  probable aminotransferase TAT3 [KO:K00815] [EC:2.6.1.5]
108841903  probable aminotransferase TAT1 [KO:K00815] [EC:2.6.1.5]
108854582  probable aminotransferase TAT3 [KO:K00815] [EC:2.6.1.5]
108853702  probable aminotransferase TAT4 [KO:K00815] [EC:2.6.1.5]
108852514  S-alkyl-thiohydroximate lyase SUR1-like [KO:K00815] [EC:2.6.1.5]
108813278  tyrosine aminotransferase [KO:K00815] [EC:2.6.1.5]
130502282  probable aminotransferase TAT4 [KO:K00815] [EC:2.6.1.5]
130508120  probable aminotransferase TAT1 [KO:K00815] [EC:2.6.1.5]
108836746  aromatic aminotransferase ISS1-like [KO:K00837] [EC:2.6.1.-]
108815486  aromatic aminotransferase ISS1-like [KO:K00837] [EC:2.6.1.-]
108842544  aromatic aminotransferase ISS1 isoform X1 [KO:K00837] [EC:2.6.1.-]
108824080  methionine gamma-lyase [KO:K01761] [EC:4.4.1.11]
108853226  DNA (cytosine-5)-methyltransferase 1-like [KO:K00558] [EC:2.1.1.37]
108812222  DNA (cytosine-5)-methyltransferase 1 [KO:K00558] [EC:2.1.1.37]
108850263  DNA (cytosine-5)-methyltransferase 1-like [KO:K00558] [EC:2.1.1.37]
108860301  DNA (cytosine-5)-methyltransferase CMT3 [KO:K00558] [EC:2.1.1.37]
108829897  DNA (cytosine-5)-methyltransferase 1-like [KO:K00558] [EC:2.1.1.37]
108843473  DNA (cytosine-5)-methyltransferase CMT2 isoform X1 [KO:K00558] [EC:2.1.1.37]
108807343  putative DNA (cytosine-5)-methyltransferase CMT1 [KO:K00558] [EC:2.1.1.37]
130510109  putative DNA (cytosine-5)-methyltransferase CMT1 [KO:K00558] [EC:2.1.1.37]
108827717  PWWP domain-containing protein 1 [KO:K17398] [EC:2.1.1.37]
108827718  PWWP domain-containing protein 1 [KO:K17398] [EC:2.1.1.37]
108822318  adenosylhomocysteinase 1 [KO:K01251] [EC:3.13.2.1]
108811901  LOW QUALITY PROTEIN: adenosylhomocysteinase 2 [KO:K01251] [EC:3.13.2.1]
108836201  adenosylhomocysteinase 1 [KO:K01251] [EC:3.13.2.1]
108856202  adenosylhomocysteinase 2 [KO:K01251] [EC:3.13.2.1]
108812761  adenosylhomocysteinase 2 [KO:K01251] [EC:3.13.2.1]
108805146  adenosylhomocysteinase 2 [KO:K01251] [EC:3.13.2.1]
130498866  adenosylhomocysteinase 1 [KO:K01251] [EC:3.13.2.1]
130504124  adenosylhomocysteinase 2-like [KO:K01251] [EC:3.13.2.1]
108830480  1-aminocyclopropane-1-carboxylate synthase 6 [KO:K20772] [EC:4.4.1.14]
108862661  1-aminocyclopropane-1-carboxylate synthase 2 [KO:K20772] [EC:4.4.1.14]
108861871  1-aminocyclopropane-1-carboxylate synthase-like protein 1 [KO:K20772] [EC:4.4.1.14]
108828192  1-aminocyclopropane-1-carboxylate synthase 6 [KO:K20772] [EC:4.4.1.14]
108834828  1-aminocyclopropane-1-carboxylate synthase 9 [KO:K01762] [EC:4.4.1.14]
108841986  1-aminocyclopropane-1-carboxylate synthase 8 [KO:K01762] [EC:4.4.1.14]
108852663  1-aminocyclopropane-1-carboxylate synthase 9-like [KO:K01762] [EC:4.4.1.14]
108844731  1-aminocyclopropane-1-carboxylate synthase 11 [KO:K01762] [EC:4.4.1.14]
108827978  1-aminocyclopropane-1-carboxylate synthase 5-like [KO:K01762] [EC:4.4.1.14]
108852226  1-aminocyclopropane-1-carboxylate synthase 4 [KO:K01762] [EC:4.4.1.14]
108840732  1-aminocyclopropane-1-carboxylate synthase 7 [KO:K01762] [EC:4.4.1.14]
108852117  1-aminocyclopropane-1-carboxylate synthase 7 [KO:K01762] [EC:4.4.1.14]
108861750  1-aminocyclopropane-1-carboxylate synthase 5 [KO:K01762] [EC:4.4.1.14]
130498480  1-aminocyclopropane-1-carboxylate synthase 8-like [KO:K01762] [EC:4.4.1.14]
130503545  1-aminocyclopropane-1-carboxylate synthase 5 [KO:K01762] [EC:4.4.1.14]
130506075  1-aminocyclopropane-1-carboxylate synthase 7 [KO:K01762] [EC:4.4.1.14]
130507193  1-aminocyclopropane-1-carboxylate synthase 9-like [KO:K01762] [EC:4.4.1.14]
130507600  1-aminocyclopropane-1-carboxylate synthase 7 [KO:K01762] [EC:4.4.1.14]
108829559  1-aminocyclopropane-1-carboxylate oxidase 1 [KO:K05933] [EC:1.14.17.4]
108836259  1-aminocyclopropane-1-carboxylate oxidase 5 [KO:K05933] [EC:1.14.17.4]
108809037  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
108820869  1-aminocyclopropane-1-carboxylate oxidase 5 [KO:K05933] [EC:1.14.17.4]
108828443  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
108850553  1-aminocyclopropane-1-carboxylate oxidase 3 [KO:K05933] [EC:1.14.17.4]
108834808  1-aminocyclopropane-1-carboxylate oxidase 3 [KO:K05933] [EC:1.14.17.4]
108810298  1-aminocyclopropane-1-carboxylate oxidase 5-like [KO:K05933] [EC:1.14.17.4]
108843885  aspartokinase 2, chloroplastic [KO:K00928] [EC:2.7.2.4]
108842679  aspartokinase 1, chloroplastic [KO:K00928] [EC:2.7.2.4]
108817220  aspartokinase 1, chloroplastic [KO:K00928] [EC:2.7.2.4]
108820439  aspartokinase 3, chloroplastic [KO:K00928] [EC:2.7.2.4]
108842343  bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic [KO:K12524] [EC:2.7.2.4 1.1.1.3]
108862670  bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic [KO:K12524] [EC:2.7.2.4 1.1.1.3]
108851442  uncharacterized protein LOC108851442 [KO:K00133] [EC:1.2.1.11]
108821414  uncharacterized protein LOC108821414 [KO:K00133] [EC:1.2.1.11]
108822524  uncharacterized protein LOC108822524 [KO:K00133] [EC:1.2.1.11]
130504032  uncharacterized protein LOC130504032 [KO:K00133] [EC:1.2.1.11]
108814407  uncharacterized protein LOC108814407 [KO:K00003] [EC:1.1.1.3]
108816558  cystathionine gamma-synthase 1, chloroplastic-like [KO:K01739] [EC:2.5.1.48]
108805200  cystathionine gamma-synthase 1, chloroplastic [KO:K01739] [EC:2.5.1.48]
108859429  cystathionine gamma-synthase 1, chloroplastic [KO:K01739] [EC:2.5.1.48]
108862402  branched-chain-amino-acid aminotransferase 2, chloroplastic isoform X1 [KO:K00826] [EC:2.6.1.42]
108853095  branched-chain-amino-acid aminotransferase 1, mitochondrial [KO:K00826] [EC:2.6.1.42]
108812530  branched-chain-amino-acid aminotransferase 2, chloroplastic [KO:K00826] [EC:2.6.1.42]
108843574  branched-chain-amino-acid aminotransferase 3, chloroplastic [KO:K00826] [EC:2.6.1.42]
108813098  branched-chain-amino-acid aminotransferase 2, chloroplastic isoform X1 [KO:K00826] [EC:2.6.1.42]
108832830  branched-chain-amino-acid aminotransferase 1, mitochondrial [KO:K00826] [EC:2.6.1.42]
108806231  branched-chain-amino-acid aminotransferase 3, chloroplastic isoform X1 [KO:K00826] [EC:2.6.1.42]
108821294  putative branched-chain-amino-acid aminotransferase 7 [KO:K00826] [EC:2.6.1.42]
108840698  branched-chain-amino-acid aminotransferase 6 [KO:K00826] [EC:2.6.1.42]
108805860  branched-chain-amino-acid aminotransferase 1, mitochondrial isoform X1 [KO:K00826] [EC:2.6.1.42]
130494332  branched-chain-amino-acid aminotransferase 2, chloroplastic-like isoform X1 [KO:K00826] [EC:2.6.1.42]
108818792  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
108844499  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
108813138  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
108839753  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
108859075  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial isoform X1 [KO:K00827] [EC:2.6.1.44 2.6.1.40]
108852529  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
108844445  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
130498309  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
130504118  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
130507642  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
130508310  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
130509241  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
108852473  glutamate--cysteine ligase, chloroplastic-like isoform X2 [KO:K01919] [EC:6.3.2.2]
108848743  glutamate--cysteine ligase, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
108843122  glutamate--cysteine ligase, chloroplastic [KO:K01919] [EC:6.3.2.2]
108827950  glutathione synthetase, chloroplastic [KO:K21456] [EC:6.3.2.3]
108848538  LOW QUALITY PROTEIN: glutathione synthetase, chloroplastic [KO:K21456] [EC:6.3.2.3]
108827901  aspartate aminotransferase, cytoplasmic isozyme 2 isoform X1 [KO:K14454] [EC:2.6.1.1]
108826346  aspartate aminotransferase, cytoplasmic isozyme 2 [KO:K14454] [EC:2.6.1.1]
108814416  aspartate aminotransferase, cytoplasmic isozyme 1 [KO:K14454] [EC:2.6.1.1]
108862339  aspartate aminotransferase 3, chloroplastic [KO:K14454] [EC:2.6.1.1]
108843465  aspartate aminotransferase, cytoplasmic isozyme 1 [KO:K14454] [EC:2.6.1.1]
108813306  aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
108848561  aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
108832765  aspartate aminotransferase, chloroplastic [KO:K00811] [EC:2.6.1.1]
108841249  aspartate aminotransferase, chloroplastic isoform X1 [KO:K00811] [EC:2.6.1.1]
108849952  aspartate aminotransferase, chloroplastic [KO:K00811] [EC:2.6.1.1]
108823608  thiosulfate/3-mercaptopyruvate sulfurtransferase 2 isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
108814582  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
108824092  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
108853003  L-lactate dehydrogenase B [KO:K00016] [EC:1.1.1.27]
108840665  L-lactate dehydrogenase B-like [KO:K00016] [EC:1.1.1.27]
108848827  L-lactate dehydrogenase B [KO:K00016] [EC:1.1.1.27]
108813818  bifunctional D-cysteine desulfhydrase/1-aminocyclopropane-1-carboxylate deaminase, mitochondrial [KO:K05396] [EC:4.4.1.15]
108851673  D-cysteine desulfhydrase 2, mitochondrial [KO:K05396] [EC:4.4.1.15]
108854538  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
108833893  L-cysteine desulfhydrase [KO:K22207] [EC:4.4.1.28]
108819428  malate dehydrogenase 1, cytoplasmic [KO:K00025] [EC:1.1.1.37]
108828327  malate dehydrogenase 1, cytoplasmic [KO:K00025] [EC:1.1.1.37]
108858754  malate dehydrogenase 1, cytoplasmic-like [KO:K00025] [EC:1.1.1.37]
108858764  malate dehydrogenase 1, cytoplasmic [KO:K00025] [EC:1.1.1.37]
108832452  malate dehydrogenase 1, cytoplasmic [KO:K00025] [EC:1.1.1.37]
108828185  malate dehydrogenase 3, cytoplasmic [KO:K00025] [EC:1.1.1.37]
130505786  malate dehydrogenase 1, cytoplasmic-like [KO:K00025] [EC:1.1.1.37]
108855905  malate dehydrogenase 1, peroxisomal [KO:K00026] [EC:1.1.1.37]
108818532  malate dehydrogenase 2, glyoxysomal [KO:K00026] [EC:1.1.1.37]
108822930  malate dehydrogenase 1, mitochondrial [KO:K00026] [EC:1.1.1.37]
108842356  malate dehydrogenase 2, glyoxysomal [KO:K00026] [EC:1.1.1.37]
108813294  malate dehydrogenase, chloroplastic [KO:K00026] [EC:1.1.1.37]
108833761  malate dehydrogenase 1, mitochondrial [KO:K00026] [EC:1.1.1.37]
108859076  malate dehydrogenase 1, mitochondrial [KO:K00026] [EC:1.1.1.37]
108812706  S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent), chloroplastic [KO:K22846] [EC:2.5.1.144]
108835349  S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent), chloroplastic-like [KO:K22846] [EC:2.5.1.144]
108863595  D-3-phosphoglycerate dehydrogenase 3, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
108842924  D-3-phosphoglycerate dehydrogenase 1, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
108855168  D-3-phosphoglycerate dehydrogenase 1, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
108822279  D-3-phosphoglycerate dehydrogenase 2, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
108857706  D-3-phosphoglycerate dehydrogenase 3, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
108822631  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
130499217  D-3-phosphoglycerate dehydrogenase 2, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
130501395  D-3-phosphoglycerate dehydrogenase 1, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
108828739  phosphoserine aminotransferase 2, chloroplastic [KO:K00831] [EC:2.6.1.52]
108819320  phosphoserine aminotransferase 1, chloroplastic [KO:K00831] [EC:2.6.1.52]
108821612  phosphoserine aminotransferase 1, chloroplastic [KO:K00831] [EC:2.6.1.52]
Compound
C00019  S-Adenosyl-L-methionine
C00021  S-Adenosyl-L-homocysteine
C00022  Pyruvate
C00041  L-Alanine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00065  L-Serine
C00073  L-Methionine
C00094  Sulfite
C00097  L-Cysteine
C00109  2-Oxobutanoate
C00155  L-Homocysteine
C00170  5'-Methylthioadenosine
C00197  3-Phospho-D-glycerate
C00263  L-Homoserine
C00283  Hydrogen sulfide
C00409  Methanethiol
C00441  L-Aspartate 4-semialdehyde
C00491  L-Cystine
C00506  L-Cysteate
C00606  3-Sulfino-L-alanine
C00793  D-Cysteine
C00957  Mercaptopyruvate
C00979  O-Acetyl-L-serine
C01005  O-Phospho-L-serine
C01077  O-Acetyl-L-homoserine
C01118  O-Succinyl-L-homoserine
C01137  S-Adenosylmethioninamine
C01180  4-Methylthio-2-oxobutanoic acid
C01234  1-Aminocyclopropane-1-carboxylate
C01817  L-Homocystine
C01962  Thiocysteine
C02218  Dehydroalanine
C02291  L-Cystathionine
C02356  (S)-2-Aminobutanoate
C02989  L-Methionine S-oxide
C03082  4-Phospho-L-aspartate
C03089  5-Methylthio-D-ribose
C03145  N-Formylmethionine
C03232  3-Phosphonooxypyruvate
C03431  S-Inosyl-L-homocysteine
C03539  S-Ribosyl-L-homocysteine
C04188  S-Methyl-5-thio-D-ribose 1-phosphate
C04582  S-Methyl-5-thio-D-ribulose 1-phosphate
C05324  Nicotianamine
C05524  Aminoacyl-L-methionine
C05526  S-Glutathionyl-L-cysteine
C05527  3-Sulfinylpyruvate
C05528  3-Sulfopyruvate
C05823  3-Mercaptolactate
C05824  S-Sulfo-L-cysteine
C06547  Ethylene
C08276  3-(Methylthio)propanoate
C09306  Sulfur dioxide
C11437  1-Deoxy-D-xylulose 5-phosphate
C11481  HSO3-
C11499  (S)-3-Sulfolactate
C11537  (2R)-3-Sulfolactate
C15606  1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one
C15650  2,3-Diketo-5-methylthiopentyl-1-phosphate
C15651  2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate
C18049  N-Acyl-L-homoserine lactone
C19787  5'-S-Methyl-5'-thioinosine
C21015  gamma-L-Glutamyl-L-2-aminobutyrate
C21016  Ophthalmate
C22359  S-Methyl-1-thio-D-xylulose 5-phosphate
Reference
PMID:15102328
  Authors
Sekowska A, Denervaud V, Ashida H, Michoud K, Haas D, Yokota A, Danchin A
  Title
Bacterial variations on the methionine salvage pathway.
  Journal
BMC Microbiol 4:9 (2004)
DOI:10.1186/1471-2180-4-9
Reference
PMID:14551435
  Authors
Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A.
  Title
A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO.
  Journal
Science 302:286-90 (2003)
DOI:10.1126/science.1086997
Reference
PMID:12022921
  Authors
Sekowska A, Danchin A.
  Title
The methionine salvage pathway in Bacillus subtilis.
  Journal
BMC Microbiol 2:8 (2002)
DOI:10.1186/1471-2180-2-8
Reference
PMID:12670965
  Authors
Berger BJ, English S, Chan G, Knodel MH.
  Title
Methionine regeneration and aminotransferases in Bacillus subtilis, Bacillus cereus, and Bacillus anthracis.
  Journal
J Bacteriol 185:2418-31 (2003)
DOI:10.1128/JB.185.8.2418-2431.2003
Reference
PMID:17169919
  Authors
Goyer A, Collakova E, Shachar-Hill Y, Hanson AD
  Title
Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway.
  Journal
Plant Cell Physiol 48:232-42 (2007)
DOI:10.1093/pcp/pcl055
Reference
PMID:17030798
  Authors
Rebeille F, Jabrin S, Bligny R, Loizeau K, Gambonnet B, Van Wilder V, Douce R, Ravanel S
  Title
Methionine catabolism in Arabidopsis cells is initiated by a gamma-cleavage process and leads to S-methylcysteine and isoleucine syntheses.
  Journal
Proc Natl Acad Sci U S A 103:15687-92 (2006)
DOI:10.1073/pnas.0606195103
Reference
PMID:18625006
  Authors
Pirkov I, Norbeck J, Gustafsson L, Albers E
  Title
A complete inventory of all enzymes in the eukaryotic methionine salvage pathway.
  Journal
FEBS J 275:4111-20 (2008)
DOI:10.1111/j.1742-4658.2008.06552.x
Reference
PMID:18391471
  Authors
Ashida H, Saito Y, Kojima C, Yokota A
  Title
Enzymatic characterization of 5-methylthioribulose-1-phosphate dehydratase of the methionine salvage pathway in Bacillus subtilis.
  Journal
Biosci Biotechnol Biochem 72:959-67 (2008)
DOI:10.1271/bbb.70651
Reference
PMID:10613873
  Authors
Kitabatake M, So MW, Tumbula DL, Soll D
  Title
Cysteine biosynthesis pathway in the archaeon Methanosarcina barkeri encoded by acquired bacterial genes?
  Journal
J Bacteriol 182:143-5 (2000)
DOI:10.1128/JB.182.1.143-145.2000
Reference
PMID:12644499
  Authors
Mino K, Ishikawa K
  Title
Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1.
  Journal
J Bacteriol 185:2277-84 (2003)
DOI:10.1128/JB.185.7.2277-2284.2003
Reference
PMID:18520135
  Authors
Tanabe S
  Title
Development of assay methods for endogenous inorganic sulfur compounds and sulfurtransferases and evaluation of the physiological functions of bound sulfur.
  Journal
Yakugaku Zasshi 128:881-900 (2008)
DOI:10.1248/yakushi.128.881
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
PMID:19270684
  Authors
Gutierrez JA, Crowder T, Rinaldo-Matthis A, Ho MC, Almo SC, Schramm VL
  Title
Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.
  Journal
Nat Chem Biol 5:251-7 (2009)
DOI:10.1038/nchembio.153
Related
pathway
rsz00010  Glycolysis / Gluconeogenesis
rsz00250  Alanine, aspartate and glutamate metabolism
rsz00260  Glycine, serine and threonine metabolism
rsz00290  Valine, leucine and isoleucine biosynthesis
rsz00430  Taurine and hypotaurine metabolism
rsz00480  Glutathione metabolism
rsz00620  Pyruvate metabolism
rsz00640  Propanoate metabolism
rsz00770  Pantothenate and CoA biosynthesis
rsz00900  Terpenoid backbone biosynthesis
rsz00920  Sulfur metabolism
KO pathway
ko00270   
LinkDB

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