Homo sapiens (human): 10488
Help
Entry
10488 CDS
T01001
Symbol
CREB3, LUMAN, LZIP, sLZIP
Name
(RefSeq) cAMP responsive element binding protein 3
KO
K09048
cyclic AMP-responsive element-binding protein 3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04022
cGMP-PKG signaling pathway
hsa04024
cAMP signaling pathway
hsa04151
PI3K-Akt signaling pathway
hsa04152
AMPK signaling pathway
hsa04211
Longevity regulating pathway
hsa04261
Adrenergic signaling in cardiomyocytes
hsa04668
TNF signaling pathway
hsa04714
Thermogenesis
hsa04725
Cholinergic synapse
hsa04728
Dopaminergic synapse
hsa04911
Insulin secretion
hsa04915
Estrogen signaling pathway
hsa04916
Melanogenesis
hsa04918
Thyroid hormone synthesis
hsa04922
Glucagon signaling pathway
hsa04925
Aldosterone synthesis and secretion
hsa04926
Relaxin signaling pathway
hsa04927
Cortisol synthesis and secretion
hsa04928
Parathyroid hormone synthesis, secretion and action
hsa04931
Insulin resistance
hsa04934
Cushing syndrome
hsa04935
Growth hormone synthesis, secretion and action
hsa04962
Vasopressin-regulated water reabsorption
hsa05016
Huntington disease
hsa05020
Prion disease
hsa05030
Cocaine addiction
hsa05031
Amphetamine addiction
hsa05034
Alcoholism
hsa05161
Hepatitis B
hsa05163
Human cytomegalovirus infection
hsa05165
Human papillomavirus infection
hsa05166
Human T-cell leukemia virus 1 infection
hsa05203
Viral carcinogenesis
hsa05207
Chemical carcinogenesis - receptor activation
hsa05215
Prostate cancer
Network
nt06160
Human T-cell leukemia virus 1 (HTLV-1)
nt06161
Human immunodeficiency virus 1 (HIV-1)
nt06162
Hepatitis B virus (HBV)
nt06167
Human cytomegalovirus (HCMV)
nt06180
Pathogenic Escherichia coli
nt06210
ERK signaling (cancer)
nt06263
Hepatocellular carcinoma
nt06310
CRH-ACTH-cortisol signaling
nt06316
Renin-angiotensin-aldosterone signaling
nt06322
TRH-TSH-TH signaling
nt06324
GHRH-GH-IGF signaling
nt06360
Cushing syndrome
nt06461
Huntington disease
nt06465
Prion disease
nt06516
TNF signaling
Element
N00297
ACTH-cortisol signaling pathway
N00298
CYP11B1-CYP11B2 fusion to ACTH-cortisol signaling pathway
N00301
Angiotensin-aldosterone signaling pathway
N00302
Mutation-activated CACNA1D/H to angiotensin-aldosterone signaling pathway
N00303
Mutation-activated KCNJ5 to angiotensin-aldosterone signaling pathway
N00304
Mutation-inactivated ATP1A1 to angiotensin-aldosterone signaling pathway
N00305
Mutation-inactivated ATP2B3 to angiotensin-aldosterone signaling pathway
N00320
Mutation-activated PRKACA to ACTH-cortisol signaling pathway
N00321
Mutation-activated GNAS to ACTH-cortisol signaling pathway
N00322
Mutation-inactivated PRKAR1A to ACTH-cortisol signaling pathway
N00323
Mutation-inactivated PDE11A/PDE8B to ACTH-cortisol signaling pathway
N00324
CRHR-PKA-ACTH signaling pathway
N00325
Mutation-inactivated RASD1 to CRHR-PKA-ACTH signaling pathway
N00326
Mutation-activated GNAS to CRHR-PKA-ACTH signaling pathway
N00327
Mutation-inactivated PRKAR1A to CRHR-PKA-ACTH signaling pathway
N00410
DRD1-GNAS-AC-PKA signaling pathway
N00444
TNF-p38 signaling pathway
N00510
HTLV-1 Tax to CREB-mediated transcription
N00544
HBV HBx to CREB-mediated transcription
N00782
TSH-TG signaling pathway
N00910
GHRHR-PKA-GH signaling pathway
N00981
Mutation-caused aberrant Htt to CREB-mediated transcription
N01204
PRNP-PI3K-NOX2 signaling pathway
N01343
ACH-CHRN-RAS-ERK signaling pathway
N01351
E2-ER-RAS-ERK signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04668 TNF signaling pathway
10488 (CREB3)
04024 cAMP signaling pathway
10488 (CREB3)
04022 cGMP-PKG signaling pathway
10488 (CREB3)
04151 PI3K-Akt signaling pathway
10488 (CREB3)
04152 AMPK signaling pathway
10488 (CREB3)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
10488 (CREB3)
04922 Glucagon signaling pathway
10488 (CREB3)
04915 Estrogen signaling pathway
10488 (CREB3)
04926 Relaxin signaling pathway
10488 (CREB3)
04935 Growth hormone synthesis, secretion and action
10488 (CREB3)
04918 Thyroid hormone synthesis
10488 (CREB3)
04928 Parathyroid hormone synthesis, secretion and action
10488 (CREB3)
04916 Melanogenesis
10488 (CREB3)
04925 Aldosterone synthesis and secretion
10488 (CREB3)
04927 Cortisol synthesis and secretion
10488 (CREB3)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
10488 (CREB3)
09155 Excretory system
04962 Vasopressin-regulated water reabsorption
10488 (CREB3)
09156 Nervous system
04725 Cholinergic synapse
10488 (CREB3)
04728 Dopaminergic synapse
10488 (CREB3)
09149 Aging
04211 Longevity regulating pathway
10488 (CREB3)
09159 Environmental adaptation
04714 Thermogenesis
10488 (CREB3)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
10488 (CREB3)
05203 Viral carcinogenesis
10488 (CREB3)
09162 Cancer: specific types
05215 Prostate cancer
10488 (CREB3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
10488 (CREB3)
05161 Hepatitis B
10488 (CREB3)
05163 Human cytomegalovirus infection
10488 (CREB3)
05165 Human papillomavirus infection
10488 (CREB3)
09164 Neurodegenerative disease
05016 Huntington disease
10488 (CREB3)
05020 Prion disease
10488 (CREB3)
09165 Substance dependence
05030 Cocaine addiction
10488 (CREB3)
05031 Amphetamine addiction
10488 (CREB3)
05034 Alcoholism
10488 (CREB3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
10488 (CREB3)
04934 Cushing syndrome
10488 (CREB3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
10488 (CREB3)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Basic leucine zipper (bZIP)
CREB
10488 (CREB3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
bZIP_1
bZIP_2
bZIP_Maf
Motif
Other DBs
NCBI-GeneID:
10488
NCBI-ProteinID:
NP_006359
OMIM:
606443
HGNC:
2347
Ensembl:
ENSG00000107175
UniProt:
O43889
LinkDB
All DBs
Position
9:35732666..35736999
Genome browser
AA seq
371 aa
AA seq
DB search
MELELDAGDQDLLAFLLEESGDLGTAPDEAVRAPLDWALPLSEVPSDWEVDDLLCSLLSP
PASLNILSSSNPCLVHHDHTYSLPRETVSMDLESESCRKEGTQMTPQHMEELAEQEIARL
VLTDEEKSLLEKEGLILPETLPLTKTEEQILKRVRRKIRNKRSAQESRRKKKVYVGGLES
RVLKYTAQNMELQNKVQLLEEQNLSLLDQLRKLQAMVIEISNKTSSSSTCILVLLVSFCL
LLVPAMYSSDTRGSLPAEHGVLSRQLRALPSEDPYQLELPALQSEVPKDSTHQWLDGSDC
VLQAPGNTSCLLHYMPQAPSAEPPLEWPFPDLFSEPLCRGPILPLQANLTRKGGWLPTGS
PSVILQDRYSG
NT seq
1116 nt
NT seq
+upstream
nt +downstream
nt
atggagctggaattggatgctggtgaccaagacctgctggccttcctgctagaggaaagt
ggagatttggggacggcacccgatgaggccgtgagggccccactggactgggcgctgccg
ctttctgaggtaccgagcgactgggaagtagatgatttgctgtgctccctgctgagtccc
ccagcgtcgttgaacattctcagctcctccaacccctgccttgtccaccatgaccacacc
tactccctcccacgggaaactgtctctatggatctagagagtgagagctgtagaaaagag
gggacccagatgactccacagcatatggaggagctggcagagcaggagattgctaggcta
gtactgacagatgaggagaagagtctattggagaaggaggggcttattctgcctgagaca
cttcctctcactaagacagaggaacaaattctgaaacgtgtgcggaggaagattcgaaat
aaaagatctgctcaagagagccgcaggaaaaagaaggtgtatgttgggggtttagagagc
agggtcttgaaatacacagcccagaatatggagcttcagaacaaagtacagcttctggag
gaacagaatttgtcccttctagatcaactgaggaaactccaggccatggtgattgagata
tcaaacaaaaccagcagcagcagcacctgcatcttggtcctactagtctccttctgcctc
ctccttgtacctgctatgtactcctctgacacaagggggagcctgccagctgagcatgga
gtgttgtcccgccagcttcgtgccctccccagtgaggacccttaccagctggagctgcct
gccctgcagtcagaagtgccgaaagacagcacacaccagtggttggacggctcagactgt
gtactccaggcccctggcaacacttcctgcctgctgcattacatgcctcaggctcccagt
gcagagcctcccctggagtggccattccctgacctcttctcagagcctctctgccgaggt
cccatcctccccctgcaggcaaatctcacaaggaagggaggatggcttcctactggtagc
ccctctgtcattttgcaggacagatactcaggctag
DBGET
integrated database retrieval system