Entry |
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Symbol |
vanX
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Name |
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Pathway |
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Module |
M00651 | Vancomycin resistance, D-Ala-D-Lac type |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
09132 Signal transduction
02020 Two-component system
K08641 vanX; zinc D-Ala-D-Ala dipeptidase
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
K08641 vanX; zinc D-Ala-D-Ala dipeptidase
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors
K08641 vanX; zinc D-Ala-D-Ala dipeptidase
01011 Peptidoglycan biosynthesis and degradation proteins
K08641 vanX; zinc D-Ala-D-Ala dipeptidase
09183 Protein families: signaling and cellular processes
01504 Antimicrobial resistance genes
K08641 vanX; zinc D-Ala-D-Ala dipeptidase
Enzymes [BR:ko01000]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.13 Dipeptidases
3.4.13.22 D-Ala-D-Ala dipeptidase
K08641 vanX; zinc D-Ala-D-Ala dipeptidase
Peptidases and inhibitors [BR:ko01002]
Metallo peptidases
Family M15: zinc D-Ala-D-Ala carboxypeptidase family
K08641 vanX; zinc D-Ala-D-Ala dipeptidase
Peptidoglycan biosynthesis and degradation proteins [BR:ko01011]
Peptidoglycan biosynthesis and degradation
Carboxypeptidase
K08641 vanX; zinc D-Ala-D-Ala dipeptidase
Antimicrobial resistance genes [BR:ko01504]
Gene sets
Vancomycin resistance modules
Vancomycin resistance, D-Ala-D-Lac type
K08641 vanX; zinc D-Ala-D-Ala dipeptidase
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Other DBs |
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Genes |
» show all
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Reference |
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Authors |
Evers S, Courvalin P |
Title |
Regulation of VanB-type vancomycin resistance gene expression by the VanS(B)-VanR (B) two-component regulatory system in Enterococcus faecalis V583. |
Journal |
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Sequence |
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Reference |
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Authors |
Arthur M, Depardieu F, Cabanie L, Reynolds P, Courvalin P |
Title |
Requirement of the VanY and VanX D,D-peptidases for glycopeptide resistance in enterococci. |
Journal |
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Reference |
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Authors |
Tan AL, Loke P, Sim TS |
Title |
Molecular cloning and functional characterisation of VanX, a D-alanyl-D-alanine dipeptidase from Streptomyces coelicolor A3(2). |
Journal |
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Sequence |
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Reference |
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Authors |
Hong HJ, Hutchings MI, Neu JM, Wright GD, Paget MS, Buttner MJ |
Title |
Characterization of an inducible vancomycin resistance system in Streptomyces coelicolor reveals a novel gene (vanK) required for drug resistance. |
Journal |
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LinkDB |
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